DELL'ORCO, Daniele
 Distribuzione geografica
Continente #
NA - Nord America 3.336
EU - Europa 2.596
AS - Asia 2.541
SA - Sud America 376
AF - Africa 41
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.894
Nazione #
US - Stati Uniti d'America 3.246
SG - Singapore 932
GB - Regno Unito 869
CN - Cina 868
BR - Brasile 332
HK - Hong Kong 331
RU - Federazione Russa 301
IT - Italia 271
FR - Francia 234
IE - Irlanda 212
DE - Germania 207
SE - Svezia 198
FI - Finlandia 161
VN - Vietnam 161
KR - Corea 92
CA - Canada 65
ID - Indonesia 49
UA - Ucraina 38
AT - Austria 20
JP - Giappone 20
BD - Bangladesh 16
NL - Olanda 16
AR - Argentina 15
BE - Belgio 15
MX - Messico 15
IN - India 12
TR - Turchia 11
ZA - Sudafrica 11
PL - Polonia 10
IQ - Iraq 8
TG - Togo 8
CO - Colombia 7
EC - Ecuador 7
ES - Italia 7
CL - Cile 5
CZ - Repubblica Ceca 5
MA - Marocco 5
PK - Pakistan 5
RO - Romania 5
SA - Arabia Saudita 5
GR - Grecia 4
LV - Lettonia 4
AU - Australia 3
EG - Egitto 3
IL - Israele 3
LT - Lituania 3
PE - Perù 3
TN - Tunisia 3
VE - Venezuela 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
EE - Estonia 2
ET - Etiopia 2
HN - Honduras 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
KZ - Kazakistan 2
LI - Liechtenstein 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
PT - Portogallo 2
PY - Paraguay 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
UZ - Uzbekistan 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
CH - Svizzera 1
CI - Costa d'Avorio 1
CM - Camerun 1
CY - Cipro 1
DK - Danimarca 1
EU - Europa 1
GA - Gabon 1
HU - Ungheria 1
IR - Iran 1
IS - Islanda 1
KG - Kirghizistan 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
LU - Lussemburgo 1
ME - Montenegro 1
MK - Macedonia 1
MR - Mauritania 1
PA - Panama 1
PS - Palestinian Territory 1
RE - Reunion 1
SK - Slovacchia (Repubblica Slovacca) 1
TJ - Tagikistan 1
TW - Taiwan 1
Totale 8.894
Città #
Southend 766
Chandler 463
Singapore 436
Hong Kong 329
Jacksonville 280
Dallas 262
Woodbridge 258
Ann Arbor 224
Houston 213
Dublin 210
Ashburn 136
Verona 126
Beijing 118
The Dalles 98
Lawrence 94
Princeton 94
Jinan 91
Wilmington 86
Nanjing 71
Los Angeles 56
Dong Ket 52
Seoul 51
Shenyang 50
Columbus 49
New York 47
Jakarta 45
Hebei 44
Buffalo 39
Montréal 37
Munich 36
Sindelfingen 35
Redondo Beach 32
Tianjin 31
Mcallen 28
Zhengzhou 28
Helsinki 27
Nanchang 25
Santa Clara 24
São Paulo 24
Guangzhou 22
Ho Chi Minh City 22
Norwalk 22
Changsha 21
Taizhou 21
Jiaxing 19
Ningbo 19
Redwood City 19
Council Bluffs 18
Nuremberg 18
Tokyo 18
Hangzhou 17
Lappeenranta 17
Fuzhou 16
Brussels 15
Haikou 15
Lanzhou 15
Boardman 14
Chicago 14
Frankfurt am Main 14
Hanoi 13
Milan 13
Falls Church 12
San Francisco 12
Torino 11
Atlanta 10
Brooklyn 10
London 10
Seattle 10
Taiyuan 10
Vienna 10
Moscow 9
Warsaw 9
Fairfield 8
Lomé 8
Shanghai 8
Rio de Janeiro 7
Amsterdam 6
Brasília 6
Detroit 6
Toronto 6
Belo Horizonte 5
Bogotá 5
Mexico City 5
Roubaix 5
Trento 5
Calgary 4
Clearwater 4
Dearborn 4
Dhaka 4
Guarulhos 4
Johannesburg 4
Manaus 4
Montes Claros 4
Montreal 4
Porto Alegre 4
Ribeirão Preto 4
Salvador 4
Santiago 4
Stockholm 4
São José dos Campos 4
Totale 5.750
Nome #
Effects of membrane and biological target on the structural and allosteric properties of recoverin: a computational approach 178
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 143
Biochemical and biophysical characterization of a plant calmodulin: role of the N- and C-lobes in calcium binding, conformational change, and target interaction. 139
CaF2 nanoparticles and lipid nanovesicles as novel carriers of calcium sensors for targeted retinal therapy 138
CaF2 nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies 138
Allosteric communication pathways routed by Ca(2+)/Mg(2+) exchange in GCAP1 selectively switch target regulation modes 132
Rhodopsin transient complexes investigated by systems biology approaches. 130
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function 129
Conformational Changes in Calcium-Sensor Proteins under Molecular Crowding Conditions. 126
Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening 123
Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1 119
A Calcium-Relay Mechanism in Vertebrate Phototransduction 118
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 115
Biophysical properties of different GCAP1 Mutants associated with cone dystrophy 114
Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins 111
Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2) 111
A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors. 110
Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction. 109
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 109
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function. 107
Structural effects of Mg2+ on the regulatory states of Neuronal Calcium Sensors operating in vertebrate phototransduction 107
Dynamics of conformational Ca(2+)-switches in signaling networks detected by a planar plasmonic device. 106
Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein. 106
Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles. 106
Preferential cinding of Mg2+ over Ca2+ to CIB2 triggers an allosteric switch impaired in Usher Syndrome type 1J 106
Biophysical and biochemical characterization of two novel GCAP1 mutants associated with cone-rod dystrophy 104
Protein and signaling networks in vertebrate photoreceptor cells 103
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 103
Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease. 102
Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R 102
Differential Nanosecond Protein Dynamics in Homologous Calcium Sensors 101
Network-level analysis of light adaptation in rod cells under normal and altered conditions. 99
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach. 97
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A 97
Network and atomistic simulations unveil the structural determinants of mutations linked to retinal diseases. 96
Fingerprint profile of cone dystrophy related GCAP1 mutants 95
The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module. 94
A comprehensive model of the phototransduction cascade in mouse rod cells. 94
Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling. 92
Constitutive activation of guanylate cyclase by the G86R GCAP1 variant is due to "locking" cation-π interactions that impair the activator-to-inhibitor structural transition 92
Detecting single photons: A supramolecular matter? 90
The interaction network of rhodopsin involving the heterotrimeric G-protein transducin and the monomeric GTPase Rac1 is determined by distinct binding processes. 90
Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. 89
A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision 88
Unveiling biochemical and physiological consequences of cone dystrophy-related mutations in GCAP1 88
Structural effects of Mg2+ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction 87
Evolutionary-conserved allosteric properties of three neuronal calcium sensor proteins 87
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases. 86
Electrostatic contributions to the kinetics and thermodynamics of protein assembly. 86
Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin 86
A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors 86
Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. 85
Biophysical characterization of antimicrobial peptides activity: From in vitro to ex vivo techniques 85
Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias 85
Dark and photoactivated rhodopsin share common binding modes to transducin. 84
Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy. 83
Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k. 82
Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase 82
Fingerprints of calcium-binding protein conformational dynamics monitored by surface plasmon resonance 82
Aldo-Keto Reductase 1C1 (AKR1C1) as the first mutated gene in a family with nonsyndromic primary lipedema 81
Molecular properties of human Guanylate Cyclase-Activating Protein 3 (GCAP3) and its possible association with Retinitis Pigmentosa 81
Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations. 80
Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis. 80
Modeling the time evolution of the nanoparticle-protein corona in a body fluid. 79
Autosomal dominant gyrate atrophy-like choroidal dystrophy revisited: 45 years follow-up and association with a novel C1QTNF5 missense variant 79
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 78
Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein. 77
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations. 77
New age-related hearing loss candidate genes in humans: an ongoing challenge 75
Transient Complexes between Dark Rhodopsin and Transducin: Circumstantial Evidence or Physiological Necessity? 74
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 73
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods 73
Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology. 72
Rhodopsin activation follows precoupling with transducin: inferences from computational analysis. 71
Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2 71
Mutations in PLS1, encoding fimbrin, cause autosomal dominant non-syndromic hearing loss 71
Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase 70
Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance. 68
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties 68
Expanding the clinical and genetic spectrum of RAB28-related cone-rod dystrophy: pathogenicity of novel variants in Italian families 68
In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells 67
Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range 67
Impaired Ca2+ sensitivity of a novel GCAP1 variant causes cone dystrophy and leads to abnormal synaptic transmission between photoreceptors and bipolar cells 67
The Importance of the Protein Corona for Successful Nanodevice Design and Delivery 65
Simultaneous detection of reciprocal interactions between calmodulin, Ca2+ and molecular targets: a focus on the calmodulin-RyR2 complex 64
Calcium- and Integrin-Binding Protein 2 (CIB2) in physiology and disease: bright and dark sides 64
Molecular recognition of rhodopsin kinase GRK1 and recoverin is tuned by switching intra- and intermolecular electrostatic interactions 63
Incorporating phototransduction proteins in zebrafish green cone with pressure-polished patch pipettes 60
Neuronal calcium sensor GCAP1 encoded by GUCA1A exhibits heterogeneous functional properties in two cases of Retinitis Pigmentosa 58
A Novel GUCA1A Variant Associated with Cone Dystrophy Alters cGMP Signaling in Photoreceptors by Strongly Interacting with and Hyperactivating Retinal Guanylate Cyclase 58
Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes 57
Ionic displacement of Ca2+ by Pb2+ in calmodulin is affected by arrhythmia-associated mutations 56
Modulation of guanylate cyclase activating protein 1 (GCAP1) dimeric assembly by Ca2+ or Mg2+: hints to understand protein activity 55
Mutations at a split codon in the GTPase-encoding domain of OPA1 cause dominant optic atrophy through different molecular mechanisms 55
Editorial: Neuronal calcium sensors in health and disease 54
Pendred syndrome, or not Pendred syndrome? That is the question 53
Where vision begins 52
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion 44
Biallelic variants in TULP1 are associated with heterogeneous phenotypes of retinal dystrophy 42
Impact of calmodulin missense variants associated with congenital arrhythmia on the thermal stability and the degree of unfolding 42
Totale 8.841
Categoria #
all - tutte 35.824
article - articoli 32.455
book - libri 0
conference - conferenze 2.727
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 642
Totale 71.648


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021463 0 0 0 82 106 48 20 35 15 9 48 100
2021/2022662 46 178 5 20 28 11 17 96 23 22 57 159
2022/20231.364 116 130 135 226 115 304 31 94 153 7 34 19
2023/2024691 18 63 57 66 111 72 35 32 23 56 120 38
2024/20252.085 110 139 45 370 93 49 71 83 301 212 226 386
2025/20261.265 464 297 364 140 0 0 0 0 0 0 0 0
Totale 9.036