CATALOGO DEI PRODOTTI DELLA RICERCA

DELL'ORCO, Daniele
 Distribuzione geografica
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Continente #
NA - Nord America 2.508
EU - Europa 2.260
AS - Asia 1.018
SA - Sud America 6
AF - Africa 4
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.800
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Nazione #
US - Stati Uniti d'America 2.464
GB - Regno Unito 850
CN - Cina 705
IT - Italia 242
IE - Irlanda 212
FR - Francia 211
SE - Svezia 194
DE - Germania 161
RU - Federazione Russa 159
FI - Finlandia 141
SG - Singapore 132
VN - Vietnam 92
KR - Corea 44
CA - Canada 43
UA - Ucraina 34
HK - Hong Kong 19
BE - Belgio 15
NL - Olanda 11
JP - Giappone 9
RO - Romania 5
CZ - Repubblica Ceca 4
AT - Austria 3
AU - Australia 3
GR - Grecia 3
TR - Turchia 3
BR - Brasile 2
ES - Italia 2
LV - Lettonia 2
MA - Marocco 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AR - Argentina 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
CH - Svizzera 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
EE - Estonia 1
EG - Egitto 1
EU - Europa 1
HU - Ungheria 1
ID - Indonesia 1
IL - Israele 1
IN - India 1
IQ - Iraq 1
IR - Iran 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LT - Lituania 1
LU - Lussemburgo 1
ME - Montenegro 1
MY - Malesia 1
PA - Panama 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TJ - Tagikistan 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 5.800
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Città #
Southend 766
Chandler 463
Jacksonville 279
Woodbridge 257
Ann Arbor 224
Houston 213
Dublin 210
Verona 120
Ashburn 109
Beijing 107
Singapore 101
Lawrence 94
Princeton 94
Jinan 90
Wilmington 85
Nanjing 71
Dong Ket 52
Shenyang 49
Hebei 44
Seoul 43
New York 40
Montréal 37
Sindelfingen 35
Tianjin 30
Mcallen 28
Zhengzhou 28
Nanchang 25
Helsinki 22
Munich 22
Norwalk 22
Changsha 21
Taizhou 21
Ningbo 19
Redwood City 19
Jiaxing 18
Guangzhou 17
Hong Kong 17
Brussels 15
Dallas 15
Fuzhou 15
Haikou 15
Lanzhou 15
Boardman 14
Hangzhou 14
Milan 13
Falls Church 12
Torino 11
Los Angeles 9
Seattle 9
Fairfield 8
Taiyuan 8
Chicago 7
San Francisco 7
Tokyo 7
Detroit 6
Santa Clara 5
Trento 5
Dearborn 4
Tezze Sul Brenta 4
Amsterdam 3
Catanzaro 3
Clearwater 3
Lappeenranta 3
Lonigo 3
Oldenburg 3
Shanghai 3
Toronto 3
Washington 3
Aigaleo 2
Atlanta 2
Auburn Hills 2
Birmingham 2
Cento 2
Chaoyang 2
Cosenza 2
Dongguan 2
Fontaniva 2
Frankfurt am Main 2
Kent 2
Leiden 2
Limena 2
Nagold 2
Ottawa 2
Palermo 2
Prague 2
Qingdao 2
Redmond 2
San Diego 2
Strasbourg 2
Valdagno 2
Vienna 2
Xi'an 2
Adliswil 1
Almere Stad 1
Belovo 1
Bishkek 1
Bogotá 1
Bologna 1
Brasov 1
Bucharest 1
Totale 4.193
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Nome #
Effects of membrane and biological target on the structural and allosteric properties of recoverin: a computational approach 153
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 102
Rhodopsin transient complexes investigated by systems biology approaches. 102
Biochemical and biophysical characterization of a plant calmodulin: role of the N- and C-lobes in calcium binding, conformational change, and target interaction. 100
Conformational Changes in Calcium-Sensor Proteins under Molecular Crowding Conditions. 95
Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening 93
Allosteric communication pathways routed by Ca(2+)/Mg(2+) exchange in GCAP1 selectively switch target regulation modes 93
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function 92
CaF2 nanoparticles and lipid nanovesicles as novel carriers of calcium sensors for targeted retinal therapy 89
A Calcium-Relay Mechanism in Vertebrate Phototransduction 88
Dynamics of conformational Ca(2+)-switches in signaling networks detected by a planar plasmonic device. 87
Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction. 86
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function. 85
Biophysical properties of different GCAP1 Mutants associated with cone dystrophy 84
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 82
Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins 82
Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2) 82
Protein and signaling networks in vertebrate photoreceptor cells 81
CaF2 nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies 81
Network and atomistic simulations unveil the structural determinants of mutations linked to retinal diseases. 80
A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors. 79
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 78
Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein. 78
Differential Nanosecond Protein Dynamics in Homologous Calcium Sensors 78
Biophysical and biochemical characterization of two novel GCAP1 mutants associated with cone-rod dystrophy 77
Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1 77
Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles. 74
The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module. 72
Preferential cinding of Mg2+ over Ca2+ to CIB2 triggers an allosteric switch impaired in Usher Syndrome type 1J 72
Fingerprint profile of cone dystrophy related GCAP1 mutants 67
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach. 66
Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy. 65
Detecting single photons: A supramolecular matter? 65
Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling. 65
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 64
A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision 63
Constitutive activation of guanylate cyclase by the G86R GCAP1 variant is due to "locking" cation-π interactions that impair the activator-to-inhibitor structural transition 63
Structural effects of Mg2+ on the regulatory states of Neuronal Calcium Sensors operating in vertebrate phototransduction 62
Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease. 61
A comprehensive model of the phototransduction cascade in mouse rod cells. 61
Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. 60
Unveiling biochemical and physiological consequences of cone dystrophy-related mutations in GCAP1 60
Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin 59
Modeling the time evolution of the nanoparticle-protein corona in a body fluid. 58
Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. 58
Electrostatic contributions to the kinetics and thermodynamics of protein assembly. 58
Biophysical characterization of antimicrobial peptides activity: From in vitro to ex vivo techniques 58
Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations. 57
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 57
Structural effects of Mg2+ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction 57
Evolutionary-conserved allosteric properties of three neuronal calcium sensor proteins 57
Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k. 56
Transient Complexes between Dark Rhodopsin and Transducin: Circumstantial Evidence or Physiological Necessity? 56
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A 56
Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology. 55
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases. 55
Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R 55
Network-level analysis of light adaptation in rod cells under normal and altered conditions. 53
Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein. 53
Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis. 53
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 53
Dark and photoactivated rhodopsin share common binding modes to transducin. 52
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations. 52
Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase 51
Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias 51
Rhodopsin activation follows precoupling with transducin: inferences from computational analysis. 50
The Importance of the Protein Corona for Successful Nanodevice Design and Delivery 50
The interaction network of rhodopsin involving the heterotrimeric G-protein transducin and the monomeric GTPase Rac1 is determined by distinct binding processes. 50
Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2 50
Aldo-Keto Reductase 1C1 (AKR1C1) as the first mutated gene in a family with nonsyndromic primary lipedema 50
Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance. 49
Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase 48
Mutations in PLS1, encoding fimbrin, cause autosomal dominant non-syndromic hearing loss 48
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties 48
Expanding the clinical and genetic spectrum of RAB28-related cone-rod dystrophy: pathogenicity of novel variants in Italian families 46
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods 46
New age-related hearing loss candidate genes in humans: an ongoing challenge 45
Autosomal dominant gyrate atrophy-like choroidal dystrophy revisited: 45 years follow-up and association with a novel C1QTNF5 missense variant 45
Fingerprints of calcium-binding protein conformational dynamics monitored by surface plasmon resonance 44
A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors 44
Molecular recognition of rhodopsin kinase GRK1 and recoverin is tuned by switching intra- and intermolecular electrostatic interactions 44
Impaired Ca2+ sensitivity of a novel GCAP1 variant causes cone dystrophy and leads to abnormal synaptic transmission between photoreceptors and bipolar cells 41
Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range 40
Where vision begins 38
Editorial: Neuronal calcium sensors in health and disease 37
Molecular properties of human Guanylate Cyclase-Activating Protein 3 (GCAP3) and its possible association with Retinitis Pigmentosa 37
Simultaneous detection of reciprocal interactions between calmodulin, Ca2+ and molecular targets: a focus on the calmodulin-RyR2 complex 36
A Novel GUCA1A Variant Associated with Cone Dystrophy Alters cGMP Signaling in Photoreceptors by Strongly Interacting with and Hyperactivating Retinal Guanylate Cyclase 35
Modulation of guanylate cyclase activating protein 1 (GCAP1) dimeric assembly by Ca2+ or Mg2+: hints to understand protein activity 33
Calcium- and Integrin-Binding Protein 2 (CIB2) in physiology and disease: bright and dark sides 33
Incorporating phototransduction proteins in zebrafish green cone with pressure-polished patch pipettes 30
Mutations at a split codon in the GTPase-encoding domain of OPA1 cause dominant optic atrophy through different molecular mechanisms 30
Neuronal calcium sensor GCAP1 encoded by GUCA1A exhibits heterogeneous functional properties in two cases of Retinitis Pigmentosa 29
Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes 24
Pendred syndrome, or not Pendred syndrome? That is the question 22
Calmodulin variants associated with congenital arrhythmia impair selectivity for ryanodine receptors 17
Biallelic variants in TULP1 are associated with heterogeneous phenotypes of retinal dystrophy 16
Ionic displacement of Ca2+ by Pb2+ in calmodulin is affected by arrhythmia-associated mutations 16
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion 15
In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells 14
Totale 5.914
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Categoria #
all - tutte 21.686
article - articoli 19.486
book - libri 0
conference - conferenze 1.763
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 437
Totale 43.372
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020517 0 0 3 53 65 32 84 87 42 64 22 65
2020/2021763 115 150 35 82 106 48 20 35 15 9 48 100
2021/2022662 46 178 5 20 28 11 17 96 23 22 57 159
2022/20231.364 116 130 135 226 115 304 31 94 153 7 34 19
2023/2024691 18 63 57 66 111 72 35 32 23 56 120 38
2024/2025249 110 139 0 0 0 0 0 0 0 0 0 0
Totale 5.935