DELL'ORCO, Daniele
 Distribuzione geografica
Continente #
NA - Nord America 2.563
EU - Europa 2.365
AS - Asia 1.395
AF - Africa 12
SA - Sud America 7
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.346
Nazione #
US - Stati Uniti d'America 2.519
GB - Regno Unito 851
CN - Cina 803
SG - Singapore 369
IT - Italia 249
RU - Federazione Russa 241
IE - Irlanda 212
FR - Francia 211
SE - Svezia 195
DE - Germania 162
FI - Finlandia 148
VN - Vietnam 93
KR - Corea 45
CA - Canada 43
ID - Indonesia 39
UA - Ucraina 34
HK - Hong Kong 20
BE - Belgio 15
NL - Olanda 14
JP - Giappone 9
TG - Togo 8
RO - Romania 5
CZ - Repubblica Ceca 4
AT - Austria 3
AU - Australia 3
BR - Brasile 3
ES - Italia 3
GR - Grecia 3
TR - Turchia 3
EE - Estonia 2
IL - Israele 2
LV - Lettonia 2
MA - Marocco 2
PT - Portogallo 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AR - Argentina 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
CH - Svizzera 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
EU - Europa 1
HU - Ungheria 1
IN - India 1
IQ - Iraq 1
IR - Iran 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LT - Lituania 1
LU - Lussemburgo 1
ME - Montenegro 1
MY - Malesia 1
PA - Panama 1
SK - Slovacchia (Repubblica Slovacca) 1
TJ - Tagikistan 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 6.346
Città #
Southend 766
Chandler 463
Singapore 328
Jacksonville 279
Woodbridge 257
Ann Arbor 224
Houston 213
Dublin 210
Verona 121
Ashburn 111
Beijing 108
Lawrence 94
Princeton 94
Jinan 91
Wilmington 85
Nanjing 71
Dong Ket 52
Shenyang 49
Hebei 44
Seoul 44
New York 40
Jakarta 38
Montréal 37
Sindelfingen 35
Tianjin 31
Mcallen 28
Zhengzhou 28
Helsinki 27
Nanchang 25
Munich 22
Norwalk 22
Changsha 21
Guangzhou 21
Taizhou 21
Ningbo 19
Redwood City 19
Hong Kong 18
Jiaxing 18
Brussels 15
Dallas 15
Fuzhou 15
Haikou 15
Hangzhou 15
Lanzhou 15
Boardman 14
Santa Clara 14
Los Angeles 13
Milan 13
Falls Church 12
Torino 11
Seattle 9
Taiyuan 9
Fairfield 8
Lomé 8
Chicago 7
San Francisco 7
Shanghai 7
Tokyo 7
Detroit 6
Moscow 6
Amsterdam 5
Lappeenranta 5
Trento 5
Dearborn 4
Tezze Sul Brenta 4
Catanzaro 3
Clearwater 3
Frankfurt am Main 3
Lonigo 3
Oldenburg 3
Toronto 3
Washington 3
Xi'an 3
Aigaleo 2
Atlanta 2
Auburn Hills 2
Birmingham 2
Cento 2
Chaoyang 2
Cosenza 2
Dongguan 2
Fontaniva 2
Kent 2
Leiden 2
Limena 2
Lisbon 2
Nagold 2
Ottawa 2
Palermo 2
Prague 2
Qingdao 2
Redmond 2
Romola 2
San Diego 2
Strasbourg 2
São Paulo 2
Tallinn 2
Valdagno 2
Vienna 2
Adliswil 1
Totale 4.515
Nome #
Effects of membrane and biological target on the structural and allosteric properties of recoverin: a computational approach 157
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 108
Rhodopsin transient complexes investigated by systems biology approaches. 108
Biochemical and biophysical characterization of a plant calmodulin: role of the N- and C-lobes in calcium binding, conformational change, and target interaction. 107
Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening 100
Conformational Changes in Calcium-Sensor Proteins under Molecular Crowding Conditions. 100
Allosteric communication pathways routed by Ca(2+)/Mg(2+) exchange in GCAP1 selectively switch target regulation modes 99
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function 98
CaF2 nanoparticles and lipid nanovesicles as novel carriers of calcium sensors for targeted retinal therapy 96
A Calcium-Relay Mechanism in Vertebrate Phototransduction 94
Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction. 91
Biophysical properties of different GCAP1 Mutants associated with cone dystrophy 91
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function. 90
Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2) 90
Dynamics of conformational Ca(2+)-switches in signaling networks detected by a planar plasmonic device. 89
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 88
Protein and signaling networks in vertebrate photoreceptor cells 87
Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein. 87
Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins 87
Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1 85
CaF2 nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies 85
Biophysical and biochemical characterization of two novel GCAP1 mutants associated with cone-rod dystrophy 84
A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors. 83
Preferential cinding of Mg2+ over Ca2+ to CIB2 triggers an allosteric switch impaired in Usher Syndrome type 1J 83
Network and atomistic simulations unveil the structural determinants of mutations linked to retinal diseases. 82
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 82
Differential Nanosecond Protein Dynamics in Homologous Calcium Sensors 80
Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles. 79
Fingerprint profile of cone dystrophy related GCAP1 mutants 75
The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module. 74
Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling. 72
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 71
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach. 70
Structural effects of Mg2+ on the regulatory states of Neuronal Calcium Sensors operating in vertebrate phototransduction 70
Constitutive activation of guanylate cyclase by the G86R GCAP1 variant is due to "locking" cation-π interactions that impair the activator-to-inhibitor structural transition 70
Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy. 69
Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin 69
Detecting single photons: A supramolecular matter? 68
Unveiling biochemical and physiological consequences of cone dystrophy-related mutations in GCAP1 68
A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision 66
A comprehensive model of the phototransduction cascade in mouse rod cells. 66
Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R 66
Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease. 65
Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. 64
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A 64
Evolutionary-conserved allosteric properties of three neuronal calcium sensor proteins 63
Modeling the time evolution of the nanoparticle-protein corona in a body fluid. 62
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 62
Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. 61
Biophysical characterization of antimicrobial peptides activity: From in vitro to ex vivo techniques 61
Structural effects of Mg2+ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction 61
Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations. 60
Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein. 60
Transient Complexes between Dark Rhodopsin and Transducin: Circumstantial Evidence or Physiological Necessity? 60
Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias 60
Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology. 59
Electrostatic contributions to the kinetics and thermodynamics of protein assembly. 59
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases. 58
Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k. 57
Network-level analysis of light adaptation in rod cells under normal and altered conditions. 56
Dark and photoactivated rhodopsin share common binding modes to transducin. 56
Fingerprints of calcium-binding protein conformational dynamics monitored by surface plasmon resonance 56
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 56
Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis. 55
New age-related hearing loss candidate genes in humans: an ongoing challenge 55
Aldo-Keto Reductase 1C1 (AKR1C1) as the first mutated gene in a family with nonsyndromic primary lipedema 55
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations. 54
Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2 54
A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors 54
Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase 53
The Importance of the Protein Corona for Successful Nanodevice Design and Delivery 53
Autosomal dominant gyrate atrophy-like choroidal dystrophy revisited: 45 years follow-up and association with a novel C1QTNF5 missense variant 53
The interaction network of rhodopsin involving the heterotrimeric G-protein transducin and the monomeric GTPase Rac1 is determined by distinct binding processes. 52
Mutations in PLS1, encoding fimbrin, cause autosomal dominant non-syndromic hearing loss 52
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties 52
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods 52
Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance. 51
Rhodopsin activation follows precoupling with transducin: inferences from computational analysis. 51
Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase 50
Expanding the clinical and genetic spectrum of RAB28-related cone-rod dystrophy: pathogenicity of novel variants in Italian families 50
Impaired Ca2+ sensitivity of a novel GCAP1 variant causes cone dystrophy and leads to abnormal synaptic transmission between photoreceptors and bipolar cells 48
Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range 47
Molecular recognition of rhodopsin kinase GRK1 and recoverin is tuned by switching intra- and intermolecular electrostatic interactions 45
Molecular properties of human Guanylate Cyclase-Activating Protein 3 (GCAP3) and its possible association with Retinitis Pigmentosa 42
Editorial: Neuronal calcium sensors in health and disease 41
Where vision begins 40
A Novel GUCA1A Variant Associated with Cone Dystrophy Alters cGMP Signaling in Photoreceptors by Strongly Interacting with and Hyperactivating Retinal Guanylate Cyclase 40
Calcium- and Integrin-Binding Protein 2 (CIB2) in physiology and disease: bright and dark sides 39
Simultaneous detection of reciprocal interactions between calmodulin, Ca2+ and molecular targets: a focus on the calmodulin-RyR2 complex 38
Modulation of guanylate cyclase activating protein 1 (GCAP1) dimeric assembly by Ca2+ or Mg2+: hints to understand protein activity 37
Neuronal calcium sensor GCAP1 encoded by GUCA1A exhibits heterogeneous functional properties in two cases of Retinitis Pigmentosa 34
Mutations at a split codon in the GTPase-encoding domain of OPA1 cause dominant optic atrophy through different molecular mechanisms 34
Incorporating phototransduction proteins in zebrafish green cone with pressure-polished patch pipettes 32
Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes 29
In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells 26
Pendred syndrome, or not Pendred syndrome? That is the question 26
Biallelic variants in TULP1 are associated with heterogeneous phenotypes of retinal dystrophy 25
Calmodulin variants associated with congenital arrhythmia impair selectivity for ryanodine receptors 25
Ionic displacement of Ca2+ by Pb2+ in calmodulin is affected by arrhythmia-associated mutations 24
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion 21
Totale 6.433
Categoria #
all - tutte 24.860
article - articoli 22.390
book - libri 0
conference - conferenze 1.987
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 483
Totale 49.720


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020396 0 0 0 0 0 32 84 87 42 64 22 65
2020/2021763 115 150 35 82 106 48 20 35 15 9 48 100
2021/2022662 46 178 5 20 28 11 17 96 23 22 57 159
2022/20231.364 116 130 135 226 115 304 31 94 153 7 34 19
2023/2024691 18 63 57 66 111 72 35 32 23 56 120 38
2024/2025797 110 139 45 370 93 40 0 0 0 0 0 0
Totale 6.483