DELL'ORCO, Daniele
 Distribuzione geografica
Continente #
NA - Nord America 4.611
EU - Europa 4.242
AS - Asia 3.600
SA - Sud America 508
AF - Africa 84
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 13.049
Nazione #
US - Stati Uniti d'America 4.497
RU - Federazione Russa 1.709
SG - Singapore 1.409
CN - Cina 1.035
GB - Regno Unito 906
BR - Brasile 416
IT - Italia 404
HK - Hong Kong 365
VN - Vietnam 361
FR - Francia 241
IE - Irlanda 217
DE - Germania 214
SE - Svezia 201
FI - Finlandia 167
KR - Corea 161
CA - Canada 74
ID - Indonesia 62
UA - Ucraina 44
AR - Argentina 36
BD - Bangladesh 36
IN - India 32
JP - Giappone 32
AT - Austria 23
MX - Messico 23
IQ - Iraq 19
ZA - Sudafrica 19
NL - Olanda 18
PK - Pakistan 17
EC - Ecuador 16
PL - Polonia 16
BE - Belgio 15
TR - Turchia 14
CO - Colombia 13
ES - Italia 13
NG - Nigeria 12
SA - Arabia Saudita 10
CL - Cile 9
BJ - Benin 8
MA - Marocco 8
TG - Togo 8
CZ - Repubblica Ceca 6
GR - Grecia 6
LT - Lituania 6
RO - Romania 6
DO - Repubblica Dominicana 5
DZ - Algeria 5
EG - Egitto 5
PE - Perù 5
PY - Paraguay 5
TN - Tunisia 5
VE - Venezuela 5
JO - Giordania 4
LV - Lettonia 4
MY - Malesia 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
AU - Australia 3
AZ - Azerbaigian 3
BA - Bosnia-Erzegovina 3
CM - Camerun 3
HN - Honduras 3
IL - Israele 3
KE - Kenya 3
KZ - Kazakistan 3
LB - Libano 3
UZ - Uzbekistan 3
AM - Armenia 2
CI - Costa d'Avorio 2
EE - Estonia 2
ET - Etiopia 2
JM - Giamaica 2
KG - Kirghizistan 2
LI - Liechtenstein 2
NI - Nicaragua 2
NP - Nepal 2
OM - Oman 2
PH - Filippine 2
PT - Portogallo 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
BB - Barbados 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BY - Bielorussia 1
CG - Congo 1
CH - Svizzera 1
CY - Cipro 1
DK - Danimarca 1
EU - Europa 1
GA - Gabon 1
HR - Croazia 1
HU - Ungheria 1
IR - Iran 1
IS - Islanda 1
KW - Kuwait 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MD - Moldavia 1
Totale 13.036
Città #
Southend 766
Singapore 738
Ashburn 642
Moscow 565
Chandler 463
San Jose 445
Hong Kong 360
Jacksonville 280
Dallas 267
Woodbridge 258
Verona 236
Ann Arbor 224
Houston 218
The Dalles 217
Dublin 215
Beijing 148
Lawrence 94
Princeton 94
Jinan 91
Wilmington 86
Ho Chi Minh City 84
Los Angeles 75
Nanjing 71
Hanoi 64
New York 60
Dong Ket 52
Seoul 51
Shenyang 50
Columbus 49
Jakarta 49
Hebei 44
Buffalo 42
Montréal 37
Munich 37
São Paulo 37
Tianjin 36
Sindelfingen 35
Redondo Beach 32
Santa Clara 32
Tokyo 30
Helsinki 29
Mcallen 28
Zhengzhou 28
Nanchang 25
Guangzhou 24
London 24
Council Bluffs 23
Norwalk 22
Changsha 21
Taizhou 21
Frankfurt am Main 20
Lappeenranta 20
Chicago 19
Jiaxing 19
Ningbo 19
Redwood City 19
Hangzhou 18
Nuremberg 18
Atlanta 16
Brooklyn 16
Fuzhou 16
Orem 16
Brussels 15
Haikou 15
Lanzhou 15
Milan 15
Warsaw 15
Boardman 14
San Francisco 14
Falls Church 12
Vienna 12
Abuja 11
Montreal 11
Torino 11
Denver 10
Seattle 10
Taiyuan 10
Baghdad 9
Belo Horizonte 9
Haiphong 9
Johannesburg 9
Shanghai 9
Brasília 8
Chennai 8
Cotonou 8
Da Nang 8
Fairfield 8
Lomé 8
Quito 8
Rio de Janeiro 8
Amsterdam 7
Lahore 7
Mexico City 7
Porto Alegre 7
Santiago 7
Bogotá 6
Detroit 6
Dhaka 6
Paris 6
Poplar 6
Totale 8.199
Nome #
Effects of membrane and biological target on the structural and allosteric properties of recoverin: a computational approach 216
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 209
Biochemical and biophysical characterization of a plant calmodulin: role of the N- and C-lobes in calcium binding, conformational change, and target interaction. 195
CaF2 nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies 194
CaF2 nanoparticles and lipid nanovesicles as novel carriers of calcium sensors for targeted retinal therapy 186
Allosteric communication pathways routed by Ca(2+)/Mg(2+) exchange in GCAP1 selectively switch target regulation modes 186
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function 179
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 176
Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles. 173
A Calcium-Relay Mechanism in Vertebrate Phototransduction 171
Conformational Changes in Calcium-Sensor Proteins under Molecular Crowding Conditions. 168
Biophysical properties of different GCAP1 Mutants associated with cone dystrophy 167
Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins 167
Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein. 164
Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2) 164
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function. 163
Rhodopsin transient complexes investigated by systems biology approaches. 162
Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1 159
Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening 156
A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors. 156
Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R 156
Biophysical and biochemical characterization of two novel GCAP1 mutants associated with cone-rod dystrophy 155
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 155
Preferential cinding of Mg2+ over Ca2+ to CIB2 triggers an allosteric switch impaired in Usher Syndrome type 1J 153
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A 148
Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease. 146
Differential Nanosecond Protein Dynamics in Homologous Calcium Sensors 146
Aldo-Keto Reductase 1C1 (AKR1C1) as the first mutated gene in a family with nonsyndromic primary lipedema 146
Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias 146
Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction. 142
A comprehensive model of the phototransduction cascade in mouse rod cells. 140
Constitutive activation of guanylate cyclase by the G86R GCAP1 variant is due to "locking" cation-π interactions that impair the activator-to-inhibitor structural transition 139
A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors 138
In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells 137
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 137
Structural effects of Mg2+ on the regulatory states of Neuronal Calcium Sensors operating in vertebrate phototransduction 137
A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision 136
Autosomal dominant gyrate atrophy-like choroidal dystrophy revisited: 45 years follow-up and association with a novel C1QTNF5 missense variant 136
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods 133
Molecular properties of human Guanylate Cyclase-Activating Protein 3 (GCAP3) and its possible association with Retinitis Pigmentosa 133
Dynamics of conformational Ca(2+)-switches in signaling networks detected by a planar plasmonic device. 129
Fingerprint profile of cone dystrophy related GCAP1 mutants 129
A Novel GUCA1A Variant Associated with Cone Dystrophy Alters cGMP Signaling in Photoreceptors by Strongly Interacting with and Hyperactivating Retinal Guanylate Cyclase 128
Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling. 127
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach. 124
Protein and signaling networks in vertebrate photoreceptor cells 123
Biophysical characterization of antimicrobial peptides activity: From in vitro to ex vivo techniques 123
The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module. 121
Network and atomistic simulations unveil the structural determinants of mutations linked to retinal diseases. 120
Network-level analysis of light adaptation in rod cells under normal and altered conditions. 119
The interaction network of rhodopsin involving the heterotrimeric G-protein transducin and the monomeric GTPase Rac1 is determined by distinct binding processes. 119
Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range 118
Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes 117
Structural effects of Mg2+ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction 117
Unveiling biochemical and physiological consequences of cone dystrophy-related mutations in GCAP1 117
Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. 116
Evolutionary-conserved allosteric properties of three neuronal calcium sensor proteins 115
Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis. 114
Dark and photoactivated rhodopsin share common binding modes to transducin. 113
Detecting single photons: A supramolecular matter? 112
Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin 112
Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase 111
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases. 109
Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k. 109
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 109
Impaired Ca2+ sensitivity of a novel GCAP1 variant causes cone dystrophy and leads to abnormal synaptic transmission between photoreceptors and bipolar cells 109
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion 108
Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations. 107
Electrostatic contributions to the kinetics and thermodynamics of protein assembly. 107
Fingerprints of calcium-binding protein conformational dynamics monitored by surface plasmon resonance 106
Calmodulin variants associated with congenital arrhythmia impair selectivity for ryanodine receptors 105
Ionic displacement of Ca2+ by Pb2+ in calmodulin is affected by arrhythmia-associated mutations 105
Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy. 105
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties 104
Expanding the clinical and genetic spectrum of RAB28-related cone-rod dystrophy: pathogenicity of novel variants in Italian families 104
Calcium- and Integrin-Binding Protein 2 (CIB2) in physiology and disease: bright and dark sides 104
Modeling the time evolution of the nanoparticle-protein corona in a body fluid. 103
Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance. 103
New age-related hearing loss candidate genes in humans: an ongoing challenge 103
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 102
Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. 100
Mutations in PLS1, encoding fimbrin, cause autosomal dominant non-syndromic hearing loss 99
Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein. 98
Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase 97
Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2 96
Transient Complexes between Dark Rhodopsin and Transducin: Circumstantial Evidence or Physiological Necessity? 95
Biallelic variants in TULP1 are associated with heterogeneous phenotypes of retinal dystrophy 94
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations. 94
Supramolecular complexes of GCAP1: implications for inherited retinal dystrophies 92
Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology. 91
Pendred syndrome, or not Pendred syndrome? That is the question 89
Rhodopsin activation follows precoupling with transducin: inferences from computational analysis. 88
Incorporating phototransduction proteins in zebrafish green cone with pressure-polished patch pipettes 88
Molecular recognition of rhodopsin kinase GRK1 and recoverin is tuned by switching intra- and intermolecular electrostatic interactions 88
Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges 87
Impact of calmodulin missense variants associated with congenital arrhythmia on the thermal stability and the degree of unfolding 86
Simultaneous detection of reciprocal interactions between calmodulin, Ca2+ and molecular targets: a focus on the calmodulin-RyR2 complex 84
Modulation of guanylate cyclase activating protein 1 (GCAP1) dimeric assembly by Ca2+ or Mg2+: hints to understand protein activity 82
Recombinant protein delivery enables modulation of the phototransduction cascade in mouse retina 81
The Importance of the Protein Corona for Successful Nanodevice Design and Delivery 81
Totale 12.706
Categoria #
all - tutte 43.909
article - articoli 39.837
book - libri 0
conference - conferenze 3.315
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 757
Totale 87.818


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021157 0 0 0 0 0 0 0 0 0 9 48 100
2021/2022662 46 178 5 20 28 11 17 96 23 22 57 159
2022/20231.364 116 130 135 226 115 304 31 94 153 7 34 19
2023/2024691 18 63 57 66 111 72 35 32 23 56 120 38
2024/20252.085 110 139 45 370 93 49 71 83 301 212 226 386
2025/20265.424 464 297 364 893 1.376 377 575 372 385 321 0 0
Totale 13.195