DELL'ORCO, Daniele
 Distribuzione geografica
Continente #
EU - Europa 4.057
NA - Nord America 3.657
AS - Asia 3.106
SA - Sud America 464
AF - Africa 60
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 11.348
Nazione #
US - Stati Uniti d'America 3.553
RU - Federazione Russa 1.705
SG - Singapore 1.216
CN - Cina 980
GB - Regno Unito 895
BR - Brasile 395
HK - Hong Kong 335
IT - Italia 280
VN - Vietnam 258
FR - Francia 234
IE - Irlanda 213
DE - Germania 208
SE - Svezia 200
FI - Finlandia 162
KR - Corea 116
CA - Canada 71
ID - Indonesia 58
UA - Ucraina 41
AR - Argentina 29
JP - Giappone 26
BD - Bangladesh 22
AT - Austria 20
MX - Messico 19
IN - India 18
ZA - Sudafrica 17
NL - Olanda 16
BE - Belgio 15
PL - Polonia 14
IQ - Iraq 13
TR - Turchia 12
EC - Ecuador 11
ES - Italia 10
BJ - Benin 8
CO - Colombia 8
TG - Togo 8
PK - Pakistan 7
SA - Arabia Saudita 7
CL - Cile 6
MA - Marocco 6
CZ - Repubblica Ceca 5
DO - Repubblica Dominicana 5
PE - Perù 5
RO - Romania 5
TN - Tunisia 5
GR - Grecia 4
LT - Lituania 4
LV - Lettonia 4
PY - Paraguay 4
VE - Venezuela 4
AL - Albania 3
AU - Australia 3
BA - Bosnia-Erzegovina 3
DZ - Algeria 3
EG - Egitto 3
HN - Honduras 3
IL - Israele 3
KZ - Kazakistan 3
LB - Libano 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
AM - Armenia 2
AZ - Azerbaigian 2
EE - Estonia 2
ET - Etiopia 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
LI - Liechtenstein 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
PT - Portogallo 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
BB - Barbados 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CG - Congo 1
CH - Svizzera 1
CI - Costa d'Avorio 1
CM - Camerun 1
CY - Cipro 1
DK - Danimarca 1
EU - Europa 1
GA - Gabon 1
HU - Ungheria 1
IR - Iran 1
IS - Islanda 1
KG - Kirghizistan 1
KW - Kuwait 1
LK - Sri Lanka 1
LU - Lussemburgo 1
ME - Montenegro 1
MK - Macedonia 1
MN - Mongolia 1
MR - Mauritania 1
PA - Panama 1
PS - Palestinian Territory 1
Totale 11.344
Città #
Southend 766
Singapore 571
Moscow 565
Chandler 463
Hong Kong 333
Ashburn 292
Jacksonville 280
Dallas 264
Woodbridge 258
Ann Arbor 224
Houston 216
Dublin 211
The Dalles 150
Beijing 145
Verona 126
Lawrence 94
Princeton 94
Jinan 91
Wilmington 86
Nanjing 71
Los Angeles 69
Ho Chi Minh City 60
New York 54
Dong Ket 52
Seoul 51
Shenyang 50
Columbus 49
Jakarta 48
Hebei 44
Buffalo 40
Montréal 37
Munich 37
Hanoi 35
Sindelfingen 35
Tianjin 35
São Paulo 33
Redondo Beach 32
Mcallen 28
Zhengzhou 28
Helsinki 27
Santa Clara 26
Nanchang 25
Tokyo 24
London 23
Guangzhou 22
Norwalk 22
Changsha 21
Taizhou 21
Jiaxing 19
Ningbo 19
Redwood City 19
Council Bluffs 18
Lappeenranta 18
Nuremberg 18
Hangzhou 17
Atlanta 16
Fuzhou 16
Brooklyn 15
Brussels 15
Chicago 15
Haikou 15
Lanzhou 15
Boardman 14
Frankfurt am Main 14
Milan 13
Warsaw 13
Falls Church 12
San Francisco 12
Torino 11
Seattle 10
Taiyuan 10
Vienna 10
Denver 9
Montreal 9
Belo Horizonte 8
Cotonou 8
Fairfield 8
Johannesburg 8
Lomé 8
Rio de Janeiro 8
Shanghai 8
Brasília 7
Orem 7
Porto Alegre 7
Amsterdam 6
Baghdad 6
Da Nang 6
Detroit 6
Haiphong 6
Poplar 6
Stockholm 6
Toronto 6
Bogotá 5
Cape Town 5
Chennai 5
Dhaka 5
Manaus 5
Mexico City 5
Ribeirão Preto 5
Roubaix 5
Totale 6.865
Nome #
Effects of membrane and biological target on the structural and allosteric properties of recoverin: a computational approach 200
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 182
CaF2 nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies 179
Biochemical and biophysical characterization of a plant calmodulin: role of the N- and C-lobes in calcium binding, conformational change, and target interaction. 178
CaF2 nanoparticles and lipid nanovesicles as novel carriers of calcium sensors for targeted retinal therapy 169
Allosteric communication pathways routed by Ca(2+)/Mg(2+) exchange in GCAP1 selectively switch target regulation modes 169
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function 166
Conformational Changes in Calcium-Sensor Proteins under Molecular Crowding Conditions. 154
Effective delivery of recombinant proteins to rod photoreceptors via lipid nanovesicles. 151
Rhodopsin transient complexes investigated by systems biology approaches. 151
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 151
Biophysical properties of different GCAP1 Mutants associated with cone dystrophy 150
A Calcium-Relay Mechanism in Vertebrate Phototransduction 149
Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2) 148
Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein. 147
Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins 146
Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening 142
Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1 141
Structural plasticity of calmodulin on the surface of CaF2 nanoparticles preserves its biological function. 140
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 139
Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R 137
A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors. 136
Biophysical and biochemical characterization of two novel GCAP1 mutants associated with cone-rod dystrophy 136
Preferential cinding of Mg2+ over Ca2+ to CIB2 triggers an allosteric switch impaired in Usher Syndrome type 1J 136
Differential Nanosecond Protein Dynamics in Homologous Calcium Sensors 133
A comprehensive model of the phototransduction cascade in mouse rod cells. 129
Structural effects of Mg2+ on the regulatory states of Neuronal Calcium Sensors operating in vertebrate phototransduction 127
Constitutive activation of guanylate cyclase by the G86R GCAP1 variant is due to "locking" cation-π interactions that impair the activator-to-inhibitor structural transition 127
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A 126
Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction. 124
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 124
A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors 121
Aldo-Keto Reductase 1C1 (AKR1C1) as the first mutated gene in a family with nonsyndromic primary lipedema 121
A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision 120
Dynamics of conformational Ca(2+)-switches in signaling networks detected by a planar plasmonic device. 119
Autosomal dominant gyrate atrophy-like choroidal dystrophy revisited: 45 years follow-up and association with a novel C1QTNF5 missense variant 119
Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias 119
Systems biochemistry approaches to vertebrate phototransduction: towards a molecular understanding of disease. 115
Protein and signaling networks in vertebrate photoreceptor cells 114
In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells 113
Biophysical characterization of antimicrobial peptides activity: From in vitro to ex vivo techniques 112
Fingerprint profile of cone dystrophy related GCAP1 mutants 112
In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach. 111
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods 111
Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling. 110
A Novel GUCA1A Variant Associated with Cone Dystrophy Alters cGMP Signaling in Photoreceptors by Strongly Interacting with and Hyperactivating Retinal Guanylate Cyclase 110
Network-level analysis of light adaptation in rod cells under normal and altered conditions. 109
Molecular properties of human Guanylate Cyclase-Activating Protein 3 (GCAP3) and its possible association with Retinitis Pigmentosa 108
The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module. 107
Network and atomistic simulations unveil the structural determinants of mutations linked to retinal diseases. 107
Structural effects of Mg2+ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction 105
Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes. 102
The interaction network of rhodopsin involving the heterotrimeric G-protein transducin and the monomeric GTPase Rac1 is determined by distinct binding processes. 102
Detecting single photons: A supramolecular matter? 101
Unveiling biochemical and physiological consequences of cone dystrophy-related mutations in GCAP1 101
Dark and photoactivated rhodopsin share common binding modes to transducin. 100
Evolutionary-conserved allosteric properties of three neuronal calcium sensor proteins 100
Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin 99
Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range 99
Quantitative structure-activity relationship analysis of canonical inhibitors of serine proteases. 98
Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase 98
Probing fragment complementation by rigid-body docking: in silico reconstitution of calbindin D9k. 97
Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy. 96
Monomeric dark rhodopsin holds the molecular determinants for transducin recognition: insights from computational analysis. 96
Electrostatic contributions to the kinetics and thermodynamics of protein assembly. 96
Involvement of the calcium sensor GCAP1 in hereditary cone dystrophies. 95
Homodimerization of neurotensin 1 receptor involves helices 1, 2, and 4: insights from quaternary structure predictions and dimerization free energy estimations. 95
Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes 93
Fingerprints of calcium-binding protein conformational dynamics monitored by surface plasmon resonance 93
Impaired Ca2+ sensitivity of a novel GCAP1 variant causes cone dystrophy and leads to abnormal synaptic transmission between photoreceptors and bipolar cells 93
Modeling the time evolution of the nanoparticle-protein corona in a body fluid. 92
Single Amino Acid Contributions to Binding Affinity in Enzyme-Inhibitor Interactions: a Docking-Based Screening of BPTI-Beta Trypsin interaction 92
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties 92
Calcium- and Integrin-Binding Protein 2 (CIB2) in physiology and disease: bright and dark sides 91
Quaternary structure predictions and estimation of mutational effects on the free energy of dimerization of the OMPLA protein. 89
Mathematical modeling of the protein corona: implications for nanoparticulate delivery systems 89
New age-related hearing loss candidate genes in humans: an ongoing challenge 89
In silico screening of mutational effects on transmembrane helix dimerization: insights from rigid-body docking and molecular dynamics simulations. 88
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion 86
Fast predictions of thermodynamics and kinetics of protein-protein recognition from structures: from molecular design to systems biology. 85
Calmodulin variants associated with congenital arrhythmia impair selectivity for ryanodine receptors 84
Ionic displacement of Ca2+ by Pb2+ in calmodulin is affected by arrhythmia-associated mutations 84
Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2 84
Mutations in PLS1, encoding fimbrin, cause autosomal dominant non-syndromic hearing loss 84
Transient Complexes between Dark Rhodopsin and Transducin: Circumstantial Evidence or Physiological Necessity? 83
Involvement of the recoverin C-terminal segment in recognition of the target enzyme rhodopsin kinase 82
Rhodopsin activation follows precoupling with transducin: inferences from computational analysis. 82
Quantitative detection of conformational transitions in a calcium sensor protein by surface plasmon resonance. 80
Expanding the clinical and genetic spectrum of RAB28-related cone-rod dystrophy: pathogenicity of novel variants in Italian families 79
Biallelic variants in TULP1 are associated with heterogeneous phenotypes of retinal dystrophy 76
The Importance of the Protein Corona for Successful Nanodevice Design and Delivery 75
Incorporating phototransduction proteins in zebrafish green cone with pressure-polished patch pipettes 75
Pendred syndrome, or not Pendred syndrome? That is the question 75
Impact of calmodulin missense variants associated with congenital arrhythmia on the thermal stability and the degree of unfolding 74
Molecular recognition of rhodopsin kinase GRK1 and recoverin is tuned by switching intra- and intermolecular electrostatic interactions 73
Simultaneous detection of reciprocal interactions between calmodulin, Ca2+ and molecular targets: a focus on the calmodulin-RyR2 complex 73
Supramolecular complexes of GCAP1: implications for inherited retinal dystrophies 71
Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges 69
Neuronal calcium sensor GCAP1 encoded by GUCA1A exhibits heterogeneous functional properties in two cases of Retinitis Pigmentosa 69
Modulation of guanylate cyclase activating protein 1 (GCAP1) dimeric assembly by Ca2+ or Mg2+: hints to understand protein activity 68
Totale 11.137
Categoria #
all - tutte 40.606
article - articoli 36.815
book - libri 0
conference - conferenze 3.084
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 707
Totale 81.212


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021275 0 0 0 0 0 48 20 35 15 9 48 100
2021/2022662 46 178 5 20 28 11 17 96 23 22 57 159
2022/20231.364 116 130 135 226 115 304 31 94 153 7 34 19
2023/2024691 18 63 57 66 111 72 35 32 23 56 120 38
2024/20252.085 110 139 45 370 93 49 71 83 301 212 226 386
2025/20263.719 464 297 364 893 1.376 325 0 0 0 0 0 0
Totale 11.490