CATALOGO DEI PRODOTTI DELLA RICERCA
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EnglishRod photoreceptors detect single photons through a tradeoff of light collecting ability, amplification and speed. Key roles are played by rhodopsin (Rh) and transducin (Gt), whose complex supramolecular organization in outer segment disks begs for a functional interpretation. Here we review past and recent evidence of a temperature-dependence of photon detection by mammalian rods, and link this phenomenon with the putative oligomeric organization of Rh and new ideas on the dynamics of Rh-Gt interaction. Identifying an electrophysiological correlate of the supramolecular organization of Rh and Gt may shed light on the evolutionary advantage it confers to night vision.
| Titolo: | Detecting single photons: A supramolecular matter? |
| Autori: | |
| Data di pubblicazione: | 2013 |
| Rivista: | |
| Abstract: | Rod photoreceptors detect single photons through a tradeoff of light collecting ability, amplification and speed. Key roles are played by rhodopsin (Rh) and transducin (Gt), whose complex supramolecular organization in outer segment disks begs for a functional interpretation. Here we review past and recent evidence of a temperature-dependence of photon detection by mammalian rods, and link this phenomenon with the putative oligomeric organization of Rh and new ideas on the dynamics of Rh-Gt interaction. Identifying an electrophysiological correlate of the supramolecular organization of Rh and Gt may shed light on the evolutionary advantage it confers to night vision. |
| Handle: | http://hdl.handle.net/11562/490550 |
| Appare nelle tipologie: | 01.01 Articolo in Rivista |
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