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The impact of circadian rhythms on biomolecular set points: implications for disease diagnosis and monitoring

Laboratory data must be both analytically accurate and interpreted with clinically accuracy for safeguarding patient safety. However, variations – both analytical and biological – are inherent in all measurements obtained from patient samples. Biological variation observed in laboratory data can be broadly classified into two main categories: random and systematic variation. Among the systematic sources, in particular, circadian rhythms may have a significant influence on laboratory measureme...

Essere partigiani. La condizione dei resistenti nella provincia di Livorno dal secondo dopoguerra agli anni Settanta

partigiani, guerra fredda, ricostruzione

Kwoniella olivae f.a. sp. nov., a novel basidiomycetous yeast species associated with olive ecosystems

Three yeast strains of the basidiomycetous genus Kwoniella (subphylum Agaricomycotina; class Tremellomycetes; subclass Tremellomycetidae) were isolated from samples of olive oil collected in northern Italy. Analysis of the D1/D2 domains of the 26S rRNA gene (LSU) and of the complete internal transcribed spacer (ITS) region indicated that these strains displayed high sequence similarity to three other strains isolated from insect frass in olive trees in South Africa, suggesting that they are c...

Polyelectromyography Under Propofol to Differentiate Functional from Idiopathic Dystonia: A Pilot Study

Background: Functional dystonia (FD) is one of the most diagnostically challenging functional movement disorders. Phenomenological features often lack specificity, as many are also observed in idiopathic dystonia (ID) and validated biomarkers to distinguish FD from ID are currently unavailable OBJECTIVE: To investigate potential differences in muscle activity between ID and FD patients using polyelectromyography (PEMG) under anesthesia. Methods: We consecutively enrolled 10 patients with FD a...

Ethyl 4-(1H-tetrazol-1-yl)benzoate derivatives as multi-target inhibitors of cancer migration via BTK, BRAF, and FAK modulation: in silico and in vitro studies

Metastasis is the leading cause of cancer-related mortality, driven by complex processes such as cell migration and focal adhesion dynamics, which are regulated by key kinases including BTK, BRAF, and FAK. In this study, we designed, synthesized, and comprehensively evaluated a novel series of ethyl 4-(1H-tetrazol-1-yl)benzoate derivatives (Z1-Z7) as potential multi-target inhibitors of cancer metastasis. In silico analyses, including molecular docking and molecular dynamics simulations (MDs)...

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Tipologia
  • 01 Contributo in rivista72909
  • 02 Contributo in volume23951
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  • 07 Altra tipologia4910
  • 03 Libro4106
  • 06 Curatela2735
  • 05 Brevetto121
Autore
  • LIPPI, Giuseppe2541
  • SCARPA, Aldo946
  • POZZI MUCELLI, Roberto805
  • GIROLOMONI, Giampiero772
  • TARGHER, Giovanni722
  • BASSI, Claudio704
  • SCHENA, Federico663
  • FRANCHI, Massimo Piergiuseppe656
  • TANSELLA, Michele630
  • CORROCHER, Roberto625
Data di pubblicazione
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  • 2020 - 202626114
  • 2010 - 201946817
  • 2000 - 200933374
  • 1990 - 199912101
  • 1980 - 19894669
  • 1970 - 19791510
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  • 1958 - 19592
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  • ADVANCES IN INTELLIGENT SYSTEMS A...19
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  • Settore BIO/10 - Biochimica81
  • Settore MED/09 - Medicina Interna81
  • Settore MED/43 - Medicina Legale60
  • Settore BIO/11 - Biologia Molecolare51
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  • Settore M-PED/01 - Pedagogia Gene...46
  • Settore MED/08 - Anatomia Patologica46
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