CATALOGO DEI PRODOTTI DELLA RICERCA

SIMBOLO, Michele
 Distribuzione geografica
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Continente #
EU - Europa 4.977
NA - Nord America 3.761
AS - Asia 3.133
SA - Sud America 414
AF - Africa 73
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 2
Totale 12.371
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Nazione #
US - Stati Uniti d'America 3.664
RU - Federazione Russa 2.153
CN - Cina 1.181
SG - Singapore 1.119
GB - Regno Unito 827
IT - Italia 579
BR - Brasile 334
DE - Germania 327
HK - Hong Kong 318
SE - Svezia 281
IE - Irlanda 235
FR - Francia 202
VN - Vietnam 192
FI - Finlandia 130
KR - Corea 80
CA - Canada 55
NL - Olanda 52
JP - Giappone 42
UA - Ucraina 40
IN - India 38
ES - Italia 29
AT - Austria 28
MX - Messico 27
PL - Polonia 27
BE - Belgio 26
ID - Indonesia 26
AR - Argentina 25
BD - Bangladesh 22
TR - Turchia 21
IQ - Iraq 20
BJ - Benin 18
TG - Togo 16
CO - Colombia 11
EC - Ecuador 11
MA - Marocco 11
ZA - Sudafrica 11
AU - Australia 10
IR - Iran 10
SA - Arabia Saudita 9
VE - Venezuela 9
CL - Cile 7
LT - Lituania 7
UY - Uruguay 7
KG - Kirghizistan 6
PK - Pakistan 6
JO - Giordania 5
LV - Lettonia 5
NP - Nepal 5
PE - Perù 5
TW - Taiwan 5
UZ - Uzbekistan 5
AL - Albania 4
CZ - Repubblica Ceca 4
IL - Israele 4
SK - Slovacchia (Repubblica Slovacca) 4
AE - Emirati Arabi Uniti 3
BG - Bulgaria 3
CR - Costa Rica 3
KE - Kenya 3
PA - Panama 3
PH - Filippine 3
PY - Paraguay 3
TN - Tunisia 3
CH - Svizzera 2
DO - Repubblica Dominicana 2
EG - Egitto 2
EU - Europa 2
GA - Gabon 2
JM - Giamaica 2
LK - Sri Lanka 2
MY - Malesia 2
NI - Nicaragua 2
NO - Norvegia 2
PS - Palestinian Territory 2
SN - Senegal 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BO - Bolivia 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
ET - Etiopia 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
GH - Ghana 1
HR - Croazia 1
KW - Kuwait 1
KZ - Kazakistan 1
LU - Lussemburgo 1
MD - Moldavia 1
MW - Malawi 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
RO - Romania 1
RS - Serbia 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
Totale 12.368
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Città #
Moscow 742
Southend 698
Singapore 551
Chandler 507
Dallas 482
Ashburn 351
Hong Kong 309
Beijing 241
Dublin 231
Verona 226
Ann Arbor 146
Woodbridge 144
New York 143
Jacksonville 135
Munich 122
Los Angeles 91
Jinan 86
The Dalles 80
Redmond 78
Lawrence 72
Princeton 72
Wilmington 68
Shenyang 63
Ho Chi Minh City 62
Nanjing 53
Houston 50
Helsinki 49
Redondo Beach 46
Columbus 45
São Paulo 45
Tianjin 45
London 43
Zhengzhou 40
Tokyo 35
Hanoi 34
Bologna 33
Hebei 33
Milan 33
Turku 33
Buffalo 30
Santa Clara 30
Haikou 29
Ningbo 28
Sindelfingen 28
Changsha 27
Hangzhou 27
Brussels 26
Nanchang 26
Seoul 26
Frankfurt am Main 25
Nuremberg 24
Warsaw 24
Guangzhou 23
Seattle 21
Taizhou 21
Montreal 20
Poplar 20
Vienna 20
Brooklyn 19
Dearborn 19
Kent 19
Cotonou 18
Denver 18
Jakarta 18
Taiyuan 18
Orem 17
Falls Church 16
Jiaxing 16
Lomé 16
Mexico City 16
San Francisco 16
Shanghai 15
Chicago 14
Dong Ket 14
Redwood City 14
Falkenstein 13
Phoenix 13
Rio de Janeiro 13
Stockholm 13
Amsterdam 12
Norwalk 12
Rome 12
Belo Horizonte 11
Haiphong 11
Toronto 11
Atlanta 10
Baghdad 10
Boston 10
Chennai 10
Fuzhou 10
Lanzhou 10
St Louis 10
Washington 10
Council Bluffs 9
Johannesburg 9
Lappeenranta 9
Boardman 8
Cagliari 8
Naples 8
Charlotte 7
Totale 7.334
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Nome #
MAP Kinase inhibition reshapes tumour microenvironment of mouse pancreatic cancer by depleting anti-inflammatory macrophages 258
Whole-genome landscape of pancreatic neuroendocrine tumours 253
DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples 237
Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis 229
BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing 215
Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations 212
High-throughput mutation profiling identifies novel molecular dysregulation in high-grade intraepithelial neoplasia and early gastric cancers 210
A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics 203
Diffuse gliomas in patients aged 55 years or over: A suggestion for IDH mutation testing 199
Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups 195
High-throughput mutation profiling improves diagnostic stratification of sporadic medullary thyroid carcinomas. 184
Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease 182
Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours 178
Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers 178
Reporting tumor molecular heterogeneity in histopathological diagnosis 177
Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients 176
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation 168
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas 165
Next-generation sequencing for genetic testing of familial colorectal cancer syndromes 163
Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer 162
H3K27me3 immunostaining is diagnostic and prognostic in diffuse gliomas with oligodendroglial or mixed oligoastrocytic morphology 161
Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma 158
Perihilar and distal extrahepatic cholangiocarcinomas show different genetic profiles but share MYC copy gain and TP53 mutation as independent poor prognostic markers 158
Gene expression profiling of lung atypical carcinoids and large cell neuroendocrine carcinomas identifies three transcriptomic subtypes with specific genomic alterations 158
Comparative Lesions Analysis Through a Targeted Sequencing Approach 157
Lung neuroendocrine tumours: deep sequencing of the four WHO histotypes reveals chromatin remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D 156
Preliminary results of PRINCiPe (predictors of resistance to immunotherapy with nivolumab [NIV]) study in advanced pretreated non-small cell lung cancer (APNSCLC), investigating the role of an immune genomic signature (IGS) including JAK2, JAK3, PIAS4, PTPN2, STAT3, IFNAR2 alterations 153
Extrahepatic Distal Cholangiocarcinoma vs. Pancreatic Ductal Adenocarcinoma: Histology and Molecular Profiling for Differential Diagnosis and Treatment 148
Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer 147
Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas 146
Exosomal miRNA signatures of pancreatic lesions 145
Next-Generation Histopathologic Diagnosis: A Lesson From a Hepatic Carcinosarcoma 144
FrequentNRG1fusions in Caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression 143
ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance 143
Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis 142
Anticipating EGFR Targeting in Early Stages of Lung Cancer: Leave No Stone Unturned 141
Clinical and Genomic Characterization of Pancreatic Ductal Adenocarcinoma with Signet-Ring/Poorly Cohesive Cells 140
Pro-inflammatory factors secreted by pancreatic cancers with evasive resistance to anti-VEGF treatment contribute to malignant progression by inducing EMT 136
Potential role of RICTOR copy number gain (CNG) as a key biomarker of mTOR activity: A comprehensive preclinical analysis in squamous cell lung cancer (SQLC) models 134
Germinal BRCA1-2 pathogenic variants (gBRCA1-2pv) and pancreatic cancer: epidemiology of an Italian patient cohort 134
Poorly Cohesive Gastric Cancers Showing the Transcriptomic Hallmarks of Epithelial-Mesenchymal Transition Behave Aggressively 133
Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations 130
Glioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma 130
PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer 130
Complete remission with sunitinib in a poor-risk patient with metastatic renal cell carcinoma: the fine balance between toxicity and efficacy 126
Collapse of the Plasmacytoid Dendritic Cells compartment in advanced cutaneous melanomas by components of the tumor cell secretome 126
Juvenile polyposis diagnosed with an integrated histological, immunohistochemical and molecular approach identifying new SMAD4 pathogenic variants 126
Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma 125
Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas 124
Molecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumours display divergent genomic and transcriptomic profiles 122
Techniques and New Diagnostic Technologies (Limitations, Applications) 117
Molecular Profiling of 22 Primary Atypical Meningiomas Shows the Prognostic Significance of 18q Heterozygous Loss and CDKN2A/B Homozygous Deletion on Recurrence-Free Survival 117
Long-term organoid culture of a small intestinal neuroendocrine tumor 116
Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications 116
Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model 114
Molecular and Clinical Insights in Malignant Brenner Tumor of the Testis With Liver Metastases:A Case Report 113
Undifferentiated Sarcomatoid Carcinoma of the Pancreas: From Histology and Molecular Pathology to Precision Oncology 113
An Insight on Functioning Pancreatic Neuroendocrine Neoplasms 111
Intraventricular Meningiomas: Clinical-Pathological and Genetic Features of a Monocentric Series 111
Ultra-Mutation in IDH Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enrichment 110
MULTIGENE MUTATIONAL PROFILING OF CHOLANGIOCARCINOMAS IDENTIFIES ACTIONABLE MOLECULAR SUBGROUPS 108
pRB immunostaining in the differential diagnosis between pleomorphic xanthoastrocytoma and glioblastoma with giant cells 107
ARID1A mutational status in non-small cell lung cancer: from molecular pathology to clinical implications with a focus on the relationships with EGFR 106
Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization 105
Il profilo molecolare 103
Multigene mutational profiling of biliary tract cancer is related to the pattern of recurrence in surgically resected patients 101
Clinical-Pathological, Immunohistochemical, and Genetic Characterization of a Series of Posterior Pituitary Tumors 101
MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma 99
Large Cell Neuro-Endocrine Carcinoma of the Lung: Current Treatment Options and Potential Future Opportunities 98
New genomic landscapes and therapeutic targets for biliary tract cancers 97
Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex 97
Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities 97
An Overview of Circulating Biomarkers in Neuroendocrine Neoplasms: A Clinical Guide 96
Atypical meningiomas with an immunohistochemical profile consistent with hypermetabolic or proliferative molecular groups show high mitotic index, chromosomal instability, and higher recurrence risk 93
Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives 92
Metformin enhances cisplatin-induced apoptosis and prevents resistance to cisplatin in co-mutated KRAS/LKB1 Non-Small Cell Lung Cancer (NSCLC) 91
Evaluation of Correlations between Genetic Variants and High-Resolution Computed Tomography Patterns in Idiopathic Pulmonary Fibrosis 88
Pembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study 83
Most high-grade neuroendocrine tumours of the lung are likely to secondarily develop from pre-existing carcinoids: innovative findings skipping the current pathogenesis paradigm 82
Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine 82
Tissue- and liquid-biopsy based NGS profiling in advanced non-small-cell lung cancer in a real-world setting: the IMMINENT study 82
Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres) 80
Transcriptome analysis of primary sporadic neuroendocrine tumours of the intestine identified three different molecular subgroups 80
Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance 79
Exceptional Response in BRAF p.V600E-Mutant Enteric-Type Adenocarcinoma of the Lung With Cutaneous Spread: A Case Report 79
Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms 72
Patterns of gene mutations in bile duct cancers: is it time to overcome the anatomical classification? 71
Ascl1 and OTP tumor expressions are associated with Disease-Free Survival in Lung Atypical Carcinoids 70
Gene Expression Profiling of Pancreas Neuroendocrine Tumors with Different Ki67-Based Grades 69
Tubulocystic Carcinoma of Bile Ducts: A Distinct Type of Cholangiocarcinoma Associated With Adenofibroma-type Lesions 66
Metastasis of lung carcinoid in the thyroid gland after 18 years: it is never too late. A case report and review of the literature 65
Combined adenocarcinoma–atypical carcinoid of the lung. Targeted Next-Generation Sequencing (NGS) suggests a monoclonal origin of the two components 64
Hepatocellular Carcinoma Genetic Landscape 63
Exploring the molecular and biological background of lung neuroendocrine tumours 62
Pathology of Biliary Tract Cancers 61
Prognostic and predictive implications of tumor suppressor gene alterations in non-small cell lung cancer 56
Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms 53
Loss of Primary Cilia Potentiates BRAF/MAPK Pathway Activation in Rhabdoid Colorectal Carcinoma: A Series of 21 Cases Showing Ciliary Rootlet CoiledCoil (CROCC) Alterations 53
Lung carcinoid tumours: histology and Ki-67, the eternal rivalry 50
Editorial: Primary and acquired resistance in lung cancer 36
Totale 12.535
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Categoria #
all - tutte 45.870
article - articoli 41.687
book - libri 0
conference - conferenze 1.965
curatela - curatele 0
other - altro 1.191
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.027
Totale 91.740
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021249 0 0 0 0 0 47 13 12 27 21 74 55
2021/2022824 77 227 44 70 44 18 36 51 37 17 58 145
2022/20231.484 88 172 112 256 127 351 16 84 198 17 34 29
2023/2024867 40 59 82 91 109 154 49 63 12 53 131 24
2024/20252.250 115 119 123 383 79 89 117 87 310 146 229 453
2025/20264.839 503 332 509 1.209 1.895 391 0 0 0 0 0 0
Totale 12.597