CATALOGO DEI PRODOTTI DELLA RICERCA

SIMBOLO, Michele
 Distribuzione geografica
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Continente #
NA - Nord America 3.235
EU - Europa 2.904
AS - Asia 2.436
SA - Sud America 326
AF - Africa 42
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.956
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Nazione #
US - Stati Uniti d'America 3.179
CN - Cina 1.047
SG - Singapore 766
GB - Regno Unito 756
IT - Italia 562
DE - Germania 312
HK - Hong Kong 308
BR - Brasile 288
SE - Svezia 274
IE - Irlanda 235
RU - Federazione Russa 233
FR - Francia 202
FI - Finlandia 127
KR - Corea 79
VN - Vietnam 61
NL - Olanda 49
UA - Ucraina 40
JP - Giappone 33
CA - Canada 29
AT - Austria 27
BE - Belgio 26
IN - India 25
ID - Indonesia 18
ES - Italia 16
TG - Togo 16
MX - Messico 15
TR - Turchia 15
BD - Bangladesh 12
AU - Australia 10
IQ - Iraq 10
IR - Iran 10
AR - Argentina 9
PL - Polonia 9
SA - Arabia Saudita 9
MA - Marocco 7
ZA - Sudafrica 7
VE - Venezuela 6
CO - Colombia 5
KG - Kirghizistan 5
LT - Lituania 5
LV - Lettonia 5
TW - Taiwan 5
EC - Ecuador 4
IL - Israele 4
PE - Perù 4
PK - Pakistan 4
SK - Slovacchia (Repubblica Slovacca) 4
UZ - Uzbekistan 4
AL - Albania 3
BG - Bulgaria 3
CL - Cile 3
CZ - Repubblica Ceca 3
JO - Giordania 3
NP - Nepal 3
PH - Filippine 3
TN - Tunisia 3
UY - Uruguay 3
AE - Emirati Arabi Uniti 2
CH - Svizzera 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
EG - Egitto 2
EU - Europa 2
GA - Gabon 2
LK - Sri Lanka 2
NI - Nicaragua 2
NO - Norvegia 2
PA - Panama 2
PS - Palestinian Territory 2
PY - Paraguay 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BO - Bolivia 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
HR - Croazia 1
JM - Giamaica 1
KE - Kenya 1
KW - Kuwait 1
KZ - Kazakistan 1
LU - Lussemburgo 1
MD - Moldavia 1
MW - Malawi 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
RO - Romania 1
SN - Senegal 1
TT - Trinidad e Tobago 1
VC - Saint Vincent e Grenadine 1
YE - Yemen 1
Totale 8.956
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Città #
Southend 698
Chandler 507
Dallas 475
Singapore 339
Hong Kong 299
Dublin 231
Verona 226
Beijing 209
Ashburn 185
Ann Arbor 146
Woodbridge 144
Jacksonville 135
Munich 119
New York 113
Jinan 86
Redmond 78
Lawrence 72
Princeton 72
Wilmington 68
Shenyang 63
Los Angeles 62
Nanjing 53
The Dalles 48
Helsinki 47
Columbus 45
Redondo Beach 45
Tianjin 40
Zhengzhou 40
Bologna 33
Hebei 33
Houston 33
São Paulo 32
Turku 32
Buffalo 30
Milan 30
Haikou 29
Ningbo 28
Sindelfingen 28
Changsha 27
Hangzhou 27
Brussels 26
Nanchang 26
Seoul 26
Tokyo 26
Frankfurt am Main 24
Guangzhou 23
Nuremberg 22
Santa Clara 22
Taizhou 21
Seattle 20
Dearborn 19
Kent 19
Vienna 19
Jakarta 18
Taiyuan 18
Falls Church 16
Jiaxing 16
Lomé 16
San Francisco 16
London 15
Shanghai 15
Dong Ket 14
Redwood City 14
Hanoi 12
Norwalk 12
Rio de Janeiro 12
Belo Horizonte 11
Brooklyn 11
Ho Chi Minh City 11
Amsterdam 10
Chicago 10
Fuzhou 10
Lanzhou 10
Mexico City 10
Rome 10
Washington 10
Council Bluffs 9
Lappeenranta 9
Moscow 9
St Louis 9
Cagliari 8
Chions 7
Curitiba 7
Madrid 7
Phoenix 7
Toronto 7
Warsaw 7
Auburn Hills 6
Boardman 6
Boydton 6
Brescia 6
Dongguan 6
Fairfield 6
Johannesburg 6
Melbourne 6
Porto Alegre 6
Riyadh 6
Stockholm 6
Atlanta 5
Bishkek 5
Totale 5.759
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Nome #
MAP Kinase inhibition reshapes tumour microenvironment of mouse pancreatic cancer by depleting anti-inflammatory macrophages 206
Whole-genome landscape of pancreatic neuroendocrine tumours 206
DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples 196
Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis 183
BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing 180
Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations 174
High-throughput mutation profiling identifies novel molecular dysregulation in high-grade intraepithelial neoplasia and early gastric cancers 170
A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics 160
Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups 152
Reporting tumor molecular heterogeneity in histopathological diagnosis 146
Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients 144
Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease 143
Diffuse gliomas in patients aged 55 years or over: A suggestion for IDH mutation testing 141
Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours 135
High-throughput mutation profiling improves diagnostic stratification of sporadic medullary thyroid carcinomas. 134
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas 130
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation 130
Lung neuroendocrine tumours: deep sequencing of the four WHO histotypes reveals chromatin remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D 127
Perihilar and distal extrahepatic cholangiocarcinomas show different genetic profiles but share MYC copy gain and TP53 mutation as independent poor prognostic markers 124
Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers 121
Pro-inflammatory factors secreted by pancreatic cancers with evasive resistance to anti-VEGF treatment contribute to malignant progression by inducing EMT 120
Next-generation sequencing for genetic testing of familial colorectal cancer syndromes 119
Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer 114
PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer 114
Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas 113
Next-Generation Histopathologic Diagnosis: A Lesson From a Hepatic Carcinosarcoma 112
Complete remission with sunitinib in a poor-risk patient with metastatic renal cell carcinoma: the fine balance between toxicity and efficacy 112
Gene expression profiling of lung atypical carcinoids and large cell neuroendocrine carcinomas identifies three transcriptomic subtypes with specific genomic alterations 111
Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma 110
Preliminary results of PRINCiPe (predictors of resistance to immunotherapy with nivolumab [NIV]) study in advanced pretreated non-small cell lung cancer (APNSCLC), investigating the role of an immune genomic signature (IGS) including JAK2, JAK3, PIAS4, PTPN2, STAT3, IFNAR2 alterations 110
Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis 107
H3K27me3 immunostaining is diagnostic and prognostic in diffuse gliomas with oligodendroglial or mixed oligoastrocytic morphology 106
ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance 105
Anticipating EGFR Targeting in Early Stages of Lung Cancer: Leave No Stone Unturned 105
Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer 104
Comparative Lesions Analysis Through a Targeted Sequencing Approach 104
Techniques and New Diagnostic Technologies (Limitations, Applications) 102
Exosomal miRNA signatures of pancreatic lesions 101
Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations 98
Clinical and Genomic Characterization of Pancreatic Ductal Adenocarcinoma with Signet-Ring/Poorly Cohesive Cells 97
FrequentNRG1fusions in Caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression 96
Ultra-Mutation in IDH Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enrichment 96
Potential role of RICTOR copy number gain (CNG) as a key biomarker of mTOR activity: A comprehensive preclinical analysis in squamous cell lung cancer (SQLC) models 96
Collapse of the Plasmacytoid Dendritic Cells compartment in advanced cutaneous melanomas by components of the tumor cell secretome 94
MULTIGENE MUTATIONAL PROFILING OF CHOLANGIOCARCINOMAS IDENTIFIES ACTIONABLE MOLECULAR SUBGROUPS 92
Molecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumours display divergent genomic and transcriptomic profiles 90
Juvenile polyposis diagnosed with an integrated histological, immunohistochemical and molecular approach identifying new SMAD4 pathogenic variants 90
Extrahepatic Distal Cholangiocarcinoma vs. Pancreatic Ductal Adenocarcinoma: Histology and Molecular Profiling for Differential Diagnosis and Treatment 89
Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model 89
Germinal BRCA1-2 pathogenic variants (gBRCA1-2pv) and pancreatic cancer: epidemiology of an Italian patient cohort 89
Glioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma 88
Undifferentiated Sarcomatoid Carcinoma of the Pancreas: From Histology and Molecular Pathology to Precision Oncology 86
New genomic landscapes and therapeutic targets for biliary tract cancers 84
Il profilo molecolare 84
Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex 83
Multigene mutational profiling of biliary tract cancer is related to the pattern of recurrence in surgically resected patients 81
Molecular Profiling of 22 Primary Atypical Meningiomas Shows the Prognostic Significance of 18q Heterozygous Loss and CDKN2A/B Homozygous Deletion on Recurrence-Free Survival 81
pRB immunostaining in the differential diagnosis between pleomorphic xanthoastrocytoma and glioblastoma with giant cells 79
Metformin enhances cisplatin-induced apoptosis and prevents resistance to cisplatin in co-mutated KRAS/LKB1 Non-Small Cell Lung Cancer (NSCLC) 79
Molecular and Clinical Insights in Malignant Brenner Tumor of the Testis With Liver Metastases:A Case Report 79
Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas 78
MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma 78
Intraventricular Meningiomas: Clinical-Pathological and Genetic Features of a Monocentric Series 78
Poorly Cohesive Gastric Cancers Showing the Transcriptomic Hallmarks of Epithelial-Mesenchymal Transition Behave Aggressively 77
Clinical-Pathological, Immunohistochemical, and Genetic Characterization of a Series of Posterior Pituitary Tumors 76
Evaluation of Correlations between Genetic Variants and High-Resolution Computed Tomography Patterns in Idiopathic Pulmonary Fibrosis 76
Large Cell Neuro-Endocrine Carcinoma of the Lung: Current Treatment Options and Potential Future Opportunities 73
Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma 73
Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine 72
Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities 71
Most high-grade neuroendocrine tumours of the lung are likely to secondarily develop from pre-existing carcinoids: innovative findings skipping the current pathogenesis paradigm 70
Long-term organoid culture of a small intestinal neuroendocrine tumor 68
Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications 68
Pembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study 68
Patterns of gene mutations in bile duct cancers: is it time to overcome the anatomical classification? 65
An Insight on Functioning Pancreatic Neuroendocrine Neoplasms 64
An Overview of Circulating Biomarkers in Neuroendocrine Neoplasms: A Clinical Guide 61
Gene Expression Profiling of Pancreas Neuroendocrine Tumors with Different Ki67-Based Grades 56
Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms 55
Metastasis of lung carcinoid in the thyroid gland after 18 years: it is never too late. A case report and review of the literature 55
Atypical meningiomas with an immunohistochemical profile consistent with hypermetabolic or proliferative molecular groups show high mitotic index, chromosomal instability, and higher recurrence risk 54
Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance 51
Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization 49
Exploring the molecular and biological background of lung neuroendocrine tumours 49
Transcriptome analysis of primary sporadic neuroendocrine tumours of the intestine identified three different molecular subgroups 48
ARID1A mutational status in non-small cell lung cancer: from molecular pathology to clinical implications with a focus on the relationships with EGFR 47
Ascl1 and OTP tumor expressions are associated with Disease-Free Survival in Lung Atypical Carcinoids 43
Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres) 43
Exceptional Response in BRAF p.V600E-Mutant Enteric-Type Adenocarcinoma of the Lung With Cutaneous Spread: A Case Report 43
Tissue- and liquid-biopsy based NGS profiling in advanced non-small-cell lung cancer in a real-world setting: the IMMINENT study 42
Tubulocystic Carcinoma of Bile Ducts: A Distinct Type of Cholangiocarcinoma Associated With Adenofibroma-type Lesions 40
Lung carcinoid tumours: histology and Ki-67, the eternal rivalry 38
Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives 36
Loss of Primary Cilia Potentiates BRAF/MAPK Pathway Activation in Rhabdoid Colorectal Carcinoma: A Series of 21 Cases Showing Ciliary Rootlet CoiledCoil (CROCC) Alterations 34
Pathology of Biliary Tract Cancers 33
Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms 31
Combined adenocarcinoma–atypical carcinoid of the lung. Targeted Next-Generation Sequencing (NGS) suggests a monoclonal origin of the two components 29
Editorial: Primary and acquired resistance in lung cancer 25
Hepatocellular Carcinoma Genetic Landscape 22
Oncocytic and spindle cell typical carcinoids of lung: different immunophenotype and biological behavior 20
Totale 9.170
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Categoria #
all - tutte 39.559
article - articoli 35.930
book - libri 0
conference - conferenze 1.728
curatela - curatele 0
other - altro 1.065
patent - brevetti 0
selected - selezionate 0
volume - volumi 836
Totale 79.118
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021404 0 0 0 91 64 47 13 12 27 21 74 55
2021/2022824 77 227 44 70 44 18 36 51 37 17 58 145
2022/20231.484 88 172 112 256 127 351 16 84 198 17 34 29
2023/2024867 40 59 82 91 109 154 49 63 12 53 131 24
2024/20252.250 115 119 123 383 79 89 117 87 310 146 229 453
2025/20261.420 503 332 509 76 0 0 0 0 0 0 0 0
Totale 9.178