Simbolo, Michele
 Distribuzione geografica
Continente #
EU - Europa 2.473
NA - Nord America 2.219
AS - Asia 1.374
AF - Africa 22
SA - Sud America 11
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.111
Nazione #
US - Stati Uniti d'America 2.205
CN - Cina 919
GB - Regno Unito 735
IT - Italia 472
SG - Singapore 306
SE - Svezia 270
IE - Irlanda 233
RU - Federazione Russa 227
FR - Francia 186
DE - Germania 155
FI - Finlandia 84
UA - Ucraina 34
KR - Corea 28
VN - Vietnam 27
BE - Belgio 22
JP - Giappone 21
TG - Togo 16
HK - Hong Kong 15
AT - Austria 14
ID - Indonesia 12
NL - Olanda 12
AU - Australia 10
CA - Canada 10
IR - Iran 10
TR - Turchia 9
IN - India 5
KG - Kirghizistan 5
LV - Lettonia 5
MA - Marocco 5
BR - Brasile 4
BG - Bulgaria 3
CZ - Repubblica Ceca 3
ES - Italia 3
IL - Israele 3
SA - Arabia Saudita 3
AL - Albania 2
CL - Cile 2
CR - Costa Rica 2
EU - Europa 2
LK - Sri Lanka 2
NO - Norvegia 2
PH - Filippine 2
PL - Polonia 2
SK - Slovacchia (Repubblica Slovacca) 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
AR - Argentina 1
AZ - Azerbaigian 1
BO - Bolivia 1
BY - Bielorussia 1
CH - Svizzera 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
FK - Isole Falkland (Malvinas) 1
LT - Lituania 1
LU - Lussemburgo 1
MD - Moldavia 1
MX - Messico 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PK - Pakistan 1
RO - Romania 1
TW - Taiwan 1
Totale 6.111
Città #
Southend 698
Chandler 507
Singapore 268
Dublin 229
Beijing 191
Verona 190
Ann Arbor 146
Woodbridge 143
Jacksonville 134
Ashburn 118
New York 100
Jinan 86
Redmond 78
Lawrence 72
Princeton 72
Wilmington 68
Shenyang 63
Nanjing 53
Helsinki 40
Tianjin 35
Zhengzhou 35
Hebei 33
Houston 33
Bologna 32
Haikou 29
Ningbo 28
Sindelfingen 28
Nanchang 26
Seoul 24
Changsha 23
Milan 23
Brussels 22
Hangzhou 22
Taizhou 21
Guangzhou 19
Kent 19
Dearborn 18
Seattle 18
Falls Church 16
Jiaxing 16
Lomé 16
Santa Clara 16
Tokyo 16
Dallas 15
Taiyuan 15
Dong Ket 14
Munich 14
Redwood City 14
Vienna 14
Los Angeles 13
Jakarta 12
Norwalk 12
Fuzhou 10
Washington 10
Moscow 9
Shanghai 9
Cagliari 8
Hong Kong 8
Chions 7
Lanzhou 7
Auburn Hills 6
Boardman 6
Boydton 6
Dongguan 6
Fairfield 6
Melbourne 6
Amsterdam 5
Bishkek 5
Brescia 5
Lappeenranta 5
Rome 5
San Francisco 5
Zanjan 5
Bressanone 4
Chicago 4
Düsseldorf 4
Lancaster 4
London 4
Riga 4
Toronto 4
Yongin-si 4
Arzignano 3
Bolzano 3
Falkenstein 3
Menlo Park 3
Orlando 3
Osaka 3
Padova 3
Palermo 3
Paris 3
Pieve di Soligo 3
Riva 3
Sacramento 3
San Diego 3
St Louis 3
Villafranca Di Verona 3
Worcester 3
Bari 2
Brno 2
Castelnuovo 2
Totale 4.172
Nome #
Whole-genome landscape of pancreatic neuroendocrine tumours 172
DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples 168
Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis 154
BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing 142
High-throughput mutation profiling identifies novel molecular dysregulation in high-grade intraepithelial neoplasia and early gastric cancers 140
MAP Kinase inhibition reshapes tumour microenvironment of mouse pancreatic cancer by depleting anti-inflammatory macrophages 139
Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations 134
Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups 126
Reporting tumor molecular heterogeneity in histopathological diagnosis 125
Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease 120
High-throughput mutation profiling improves diagnostic stratification of sporadic medullary thyroid carcinomas. 118
Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients 113
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas 107
Pro-inflammatory factors secreted by pancreatic cancers with evasive resistance to anti-VEGF treatment contribute to malignant progression by inducing EMT 105
Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours 104
Lung neuroendocrine tumours: deep sequencing of the four WHO histotypes reveals chromatin remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D 100
Next-generation sequencing for genetic testing of familial colorectal cancer syndromes 97
Diffuse gliomas in patients aged 55 years or over: A suggestion for IDH mutation testing 95
PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer 93
A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics 92
Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas 89
Complete remission with sunitinib in a poor-risk patient with metastatic renal cell carcinoma: the fine balance between toxicity and efficacy 88
Perihilar and distal extrahepatic cholangiocarcinomas show different genetic profiles but share MYC copy gain and TP53 mutation as independent poor prognostic markers 88
Preliminary results of PRINCiPe (predictors of resistance to immunotherapy with nivolumab [NIV]) study in advanced pretreated non-small cell lung cancer (APNSCLC), investigating the role of an immune genomic signature (IGS) including JAK2, JAK3, PIAS4, PTPN2, STAT3, IFNAR2 alterations 88
Next-Generation Histopathologic Diagnosis: A Lesson From a Hepatic Carcinosarcoma 86
Techniques and New Diagnostic Technologies (Limitations, Applications) 85
Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma 83
ERG alterations and mTOR pathway activation in primary prostate carcinomas developing castration-resistance 81
Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers 80
Ultra-Mutation in IDH Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enrichment 80
Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis 79
Potential role of RICTOR copy number gain (CNG) as a key biomarker of mTOR activity: A comprehensive preclinical analysis in squamous cell lung cancer (SQLC) models 79
Gene expression profiling of lung atypical carcinoids and large cell neuroendocrine carcinomas identifies three transcriptomic subtypes with specific genomic alterations 78
Comparison Between Prognostic Classifications in De Novo Metastatic Hormone Sensitive Prostate Cancer 77
MULTIGENE MUTATIONAL PROFILING OF CHOLANGIOCARCINOMAS IDENTIFIES ACTIONABLE MOLECULAR SUBGROUPS 76
Exosomal miRNA signatures of pancreatic lesions 76
Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations 75
Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer 74
Comparative Lesions Analysis Through a Targeted Sequencing Approach 73
FrequentNRG1fusions in Caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression 72
New genomic landscapes and therapeutic targets for biliary tract cancers 71
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation 71
Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model 67
Glioblastoma with tumor-to-tumor metastasis from lung adenocarcinoma 66
Collapse of the Plasmacytoid Dendritic Cells compartment in advanced cutaneous melanomas by components of the tumor cell secretome 65
H3K27me3 immunostaining is diagnostic and prognostic in diffuse gliomas with oligodendroglial or mixed oligoastrocytic morphology 64
Il profilo molecolare 63
Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex 62
Multigene mutational profiling of biliary tract cancer is related to the pattern of recurrence in surgically resected patients 59
Germinal BRCA1-2 pathogenic variants (gBRCA1-2pv) and pancreatic cancer: epidemiology of an Italian patient cohort 59
MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma 56
Most high-grade neuroendocrine tumours of the lung are likely to secondarily develop from pre-existing carcinoids: innovative findings skipping the current pathogenesis paradigm 56
Molecular and Clinical Insights in Malignant Brenner Tumor of the Testis With Liver Metastases:A Case Report 56
Undifferentiated Sarcomatoid Carcinoma of the Pancreas: From Histology and Molecular Pathology to Precision Oncology 55
Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine 53
Molecular Profiling of 22 Primary Atypical Meningiomas Shows the Prognostic Significance of 18q Heterozygous Loss and CDKN2A/B Homozygous Deletion on Recurrence-Free Survival 53
Anticipating EGFR Targeting in Early Stages of Lung Cancer: Leave No Stone Unturned 53
Juvenile polyposis diagnosed with an integrated histological, immunohistochemical and molecular approach identifying new SMAD4 pathogenic variants 53
Metformin enhances cisplatin-induced apoptosis and prevents resistance to cisplatin in co-mutated KRAS/LKB1 Non-Small Cell Lung Cancer (NSCLC) 52
Clinical-Pathological, Immunohistochemical, and Genetic Characterization of a Series of Posterior Pituitary Tumors 51
Evaluation of Correlations between Genetic Variants and High-Resolution Computed Tomography Patterns in Idiopathic Pulmonary Fibrosis 51
Patterns of gene mutations in bile duct cancers: is it time to overcome the anatomical classification? 48
Pembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study 47
Intraventricular Meningiomas: Clinical-Pathological and Genetic Features of a Monocentric Series 47
Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas 46
Poorly Cohesive Gastric Cancers Showing the Transcriptomic Hallmarks of Epithelial-Mesenchymal Transition Behave Aggressively 46
Large Cell Neuro-Endocrine Carcinoma of the Lung: Current Treatment Options and Potential Future Opportunities 45
Molecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumours display divergent genomic and transcriptomic profiles 45
Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities 44
pRB immunostaining in the differential diagnosis between pleomorphic xanthoastrocytoma and glioblastoma with giant cells 43
Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications 40
Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma 40
Long-term organoid culture of a small intestinal neuroendocrine tumor 37
Metastasis of lung carcinoid in the thyroid gland after 18 years: it is never too late. A case report and review of the literature 37
Extrahepatic Distal Cholangiocarcinoma vs. Pancreatic Ductal Adenocarcinoma: Histology and Molecular Profiling for Differential Diagnosis and Treatment 36
Gene Expression Profiling of Pancreas Neuroendocrine Tumors with Different Ki67-Based Grades 36
Clinical and Genomic Characterization of Pancreatic Ductal Adenocarcinoma with Signet-Ring/Poorly Cohesive Cells 35
Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms 35
Exploring the molecular and biological background of lung neuroendocrine tumours 33
Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance 32
Transcriptome analysis of primary sporadic neuroendocrine tumours of the intestine identified three different molecular subgroups 31
An Insight on Functioning Pancreatic Neuroendocrine Neoplasms 29
Atypical meningiomas with an immunohistochemical profile consistent with hypermetabolic or proliferative molecular groups show high mitotic index, chromosomal instability, and higher recurrence risk 28
An Overview of Circulating Biomarkers in Neuroendocrine Neoplasms: A Clinical Guide 25
Ascl1 and OTP tumor expressions are associated with Disease-Free Survival in Lung Atypical Carcinoids 19
Lung carcinoid tumours: histology and Ki-67, the eternal rivalry 19
Exceptional Response in BRAF p.V600E-Mutant Enteric-Type Adenocarcinoma of the Lung With Cutaneous Spread: A Case Report 18
Loss of Primary Cilia Potentiates BRAF/MAPK Pathway Activation in Rhabdoid Colorectal Carcinoma: A Series of 21 Cases Showing Ciliary Rootlet CoiledCoil (CROCC) Alterations 17
Tubulocystic Carcinoma of Bile Ducts: A Distinct Type of Cholangiocarcinoma Associated With Adenofibroma-type Lesions 16
Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives 13
Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms 12
Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres) 10
Editorial: Primary and acquired resistance in lung cancer 10
Tissue- and liquid-biopsy based NGS profiling in advanced non-small-cell lung cancer in a real-world setting: the IMMINENT study 10
Totale 6.316
Categoria #
all - tutte 25.791
article - articoli 23.290
book - libri 0
conference - conferenze 1.223
curatela - curatele 0
other - altro 808
patent - brevetti 0
selected - selezionate 0
volume - volumi 470
Totale 51.582


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020469 0 0 0 0 62 53 78 35 41 52 83 65
2020/2021651 122 98 27 91 64 47 13 12 27 21 74 55
2021/2022824 77 227 44 70 44 18 36 51 37 17 58 145
2022/20231.484 88 172 112 256 127 351 16 84 198 17 34 29
2023/2024867 40 59 82 91 109 154 49 63 12 53 131 24
2024/2025808 115 119 123 383 68 0 0 0 0 0 0 0
Totale 6.316