CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 1.949
EU - Europa 1.557
AS - Asia 1.014
SA - Sud America 9
AF - Africa 6
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.541
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Nazione #
US - Stati Uniti d'America 1.942
CN - Cina 640
GB - Regno Unito 571
SG - Singapore 237
IT - Italia 161
SE - Svezia 145
FR - Francia 141
IE - Irlanda 137
RU - Federazione Russa 134
DE - Germania 93
FI - Finlandia 93
VN - Vietnam 45
UA - Ucraina 40
BE - Belgio 18
ID - Indonesia 18
KR - Corea 16
IN - India 12
TR - Turchia 12
HK - Hong Kong 6
CA - Canada 5
TG - Togo 5
TW - Taiwan 5
AU - Australia 4
CO - Colombia 4
ES - Italia 4
NL - Olanda 4
BR - Brasile 3
IR - Iran 3
JP - Giappone 3
AT - Austria 2
AZ - Azerbaigian 2
CH - Svizzera 2
CL - Cile 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
IL - Israele 2
IQ - Iraq 2
LV - Lettonia 2
PH - Filippine 2
PL - Polonia 2
SA - Arabia Saudita 2
A2 - ???statistics.table.value.countryCode.A2??? 1
DO - Repubblica Dominicana 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
MA - Marocco 1
MY - Malesia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PK - Pakistan 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
Totale 4.541
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Città #
Southend 520
Chandler 377
Jacksonville 320
Woodbridge 228
Singapore 187
Ann Arbor 175
Beijing 145
Dublin 137
Ashburn 81
Verona 77
Houston 71
Shenyang 58
Lawrence 56
Princeton 56
Jinan 54
Nanjing 53
Wilmington 48
New York 46
Hebei 34
Dong Ket 32
Ningbo 27
Redmond 25
Tianjin 20
Changsha 18
Jakarta 18
Zhengzhou 18
Brussels 17
Haikou 16
Nanchang 16
Sindelfingen 16
Helsinki 15
Seattle 15
Taizhou 15
Boardman 13
Dearborn 13
Hangzhou 13
Guangzhou 11
Santa Clara 11
Taiyuan 11
Seoul 10
Fuzhou 8
Jiaxing 8
Munich 8
Lanzhou 7
Norwalk 7
Tulsa 7
Los Angeles 6
Milan 6
Redwood City 6
Bengaluru 5
Clearwater 5
Fairfield 5
Kemerovo 5
Kent 5
Lomé 5
San Francisco 5
Bogotá 4
Bussolengo 4
Düsseldorf 4
Enterprise 4
Hong Kong 4
Lancaster 4
San Diego 4
Venice 4
Augusta 3
Bosco Chiesanuova 3
Buk-gu 3
Dallas 3
Dongguan 3
Hearne 3
Shanghai 3
São Paulo 3
Tappahannock 3
Yongin-si 3
Baku 2
Bologna 2
Boston 2
Brescia 2
College Station 2
Columbus 2
Evanston 2
Ferrara 2
Indore 2
Kochi 2
Kunming 2
Leawood 2
Madrid 2
Melbourne 2
Moscow 2
Napoli 2
Riga 2
Riva 2
Tainan City 2
Tarlac City 2
Tokyo 2
Toronto 2
Turin 2
Valkenburg 2
Vancouver 2
Vienna 2
Totale 3.285
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Nome #
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 130
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 118
Two different forms of aggregated dimers of ribonuclease A 117
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 113
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 107
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 107
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 105
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 105
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 105
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 104
Structural properties of trimers and tetramers of ribonuclease A 102
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 98
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 97
A domain-swapped RNase A dimer with implications for amyloid formation 95
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 92
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 92
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 89
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 88
Oligomerization of ribonuclease A. Structural and functional features of its multimers 87
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 87
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 87
Antitumor activity and other biological actions of oligomers of ribonuclease A 86
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 86
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 85
Investigations on onconase dimerization. 85
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 85
Some biological actions of PEG-conjugated RNase A oligomers 84
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 84
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 84
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 84
A novel biological actions acquired by ribonuclease through oligomerization 82
Human angiogenin dimerization and S28N pathogenic mutation. 79
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 78
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 74
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 73
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 72
Protein Oligomerization 72
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 72
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 70
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 70
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 69
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 69
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 68
Structures of the two 3D domain-swapped RNase A trimers 66
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 66
The two dimeric forms of RNase A 65
Oligomerization of ribonuclease A under reducing conditions 63
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 60
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 60
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 58
Platinated oligomers of bovine ribonuclease: Structure and stability 56
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 49
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 48
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 46
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 45
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 35
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 25
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 17
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 13
Protein oligomerization 12
Totale 4.620
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Categoria #
all - tutte 16.214
article - articoli 14.594
book - libri 0
conference - conferenze 1.394
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 226
Totale 32.428
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020513 0 0 0 0 42 66 66 55 29 80 59 116
2020/2021500 40 85 17 64 55 48 2 38 37 11 52 51
2021/2022464 44 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/2025488 73 88 60 211 56 0 0 0 0 0 0 0
Totale 4.620