GOTTE, Giovanni
 Distribuzione geografica
Continente #
NA - Nord America 4.214
EU - Europa 3.040
AS - Asia 2.452
SA - Sud America 334
Continente sconosciuto - Info sul continente non disponibili 90
AF - Africa 68
OC - Oceania 10
Totale 10.208
Nazione #
US - Stati Uniti d'America 4.086
RU - Federazione Russa 1.204
SG - Singapore 891
CN - Cina 815
GB - Regno Unito 629
IT - Italia 317
BR - Brasile 260
VN - Vietnam 232
HK - Hong Kong 178
SE - Svezia 161
FR - Francia 155
DE - Germania 140
IE - Irlanda 139
FI - Finlandia 121
KR - Corea 80
CA - Canada 67
BD - Bangladesh 54
UA - Ucraina 48
IN - India 44
ID - Indonesia 30
PL - Polonia 26
BE - Belgio 19
CO - Colombia 19
IQ - Iraq 19
TR - Turchia 18
AR - Argentina 17
NL - Olanda 16
MX - Messico 15
ES - Italia 14
VE - Venezuela 14
ZA - Sudafrica 14
CR - Costa Rica 13
JP - Giappone 13
MA - Marocco 13
NG - Nigeria 13
AT - Austria 10
SA - Arabia Saudita 9
PK - Pakistan 8
AU - Australia 7
UZ - Uzbekistan 7
CW - ???statistics.table.value.countryCode.CW??? 6
EC - Ecuador 6
IL - Israele 6
PH - Filippine 6
TW - Taiwan 6
BO - Bolivia 5
EG - Egitto 5
GT - Guatemala 5
HN - Honduras 5
IR - Iran 5
LT - Lituania 5
SV - El Salvador 5
TG - Togo 5
JM - Giamaica 4
KE - Kenya 4
KG - Kirghizistan 4
LV - Lettonia 4
MY - Malesia 4
PE - Perù 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
CL - Cile 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
GR - Grecia 3
JO - Giordania 3
NI - Nicaragua 3
AM - Armenia 2
AZ - Azerbaigian 2
BJ - Benin 2
BS - Bahamas 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
HR - Croazia 2
HU - Ungheria 2
ML - Mali 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
RO - Romania 2
RS - Serbia 2
SC - Seychelles 2
SI - Slovenia 2
TH - Thailandia 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BB - Barbados 1
BG - Bulgaria 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GF - Guiana Francese 1
HT - Haiti 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
Totale 10.109
Città #
Southend 520
Ashburn 512
Singapore 460
Dallas 415
San Jose 394
Moscow 383
Chandler 377
Jacksonville 321
Woodbridge 228
Beijing 178
Ann Arbor 175
Hong Kong 175
Verona 145
Dublin 139
Council Bluffs 118
New York 89
The Dalles 87
Houston 78
Ho Chi Minh City 71
Shenyang 61
Los Angeles 58
Lawrence 57
Princeton 56
Jinan 55
Nanjing 53
Wilmington 48
Hanoi 47
Santa Clara 42
Munich 37
Columbus 36
Hebei 34
Dong Ket 32
São Paulo 31
Buffalo 29
Ningbo 27
Redmond 25
Tianjin 24
Helsinki 22
Jakarta 22
Warsaw 20
Zhengzhou 20
Changsha 19
Seattle 19
Turku 19
Brussels 18
Seoul 18
Redondo Beach 17
Haikou 16
Las Vegas 16
Montreal 16
Nanchang 16
San Francisco 16
Sindelfingen 16
Brooklyn 15
Stockholm 15
Taizhou 15
Guangzhou 14
Hangzhou 14
London 14
Milan 14
Toronto 14
Abuja 13
Boardman 13
Dearborn 13
Frankfurt am Main 13
Boston 12
Denver 11
Phoenix 11
Taiyuan 11
Johannesburg 10
Brasília 9
Chicago 9
Da Nang 9
Orem 9
San José 9
Tokyo 9
Amsterdam 8
Baghdad 8
Chennai 8
Fuzhou 8
Jiaxing 8
North Bergen 8
Rome 8
Atlanta 7
Bogotá 7
Brescia 7
Curitiba 7
Lanzhou 7
Manchester 7
Norwalk 7
Tulsa 7
Athens 6
Mexico City 6
Naples 6
Redwood City 6
Tashkent 6
Vienna 6
Willemstad 6
Augusta 5
Basingstoke 5
Totale 6.347
Nome #
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 271
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 269
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 250
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 220
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 219
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 219
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 218
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 216
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 207
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 206
Structural properties of trimers and tetramers of ribonuclease A 205
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 202
Antitumor activity and other biological actions of oligomers of ribonuclease A 194
Investigations on onconase dimerization. 192
Two different forms of aggregated dimers of ribonuclease A 192
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 189
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 189
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 185
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 185
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 184
A domain-swapped RNase A dimer with implications for amyloid formation 180
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 179
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 179
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 175
Human angiogenin dimerization and S28N pathogenic mutation. 174
A novel biological actions acquired by ribonuclease through oligomerization 172
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 171
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 170
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 170
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 168
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 168
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 166
Some biological actions of PEG-conjugated RNase A oligomers 162
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 161
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 160
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 159
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 158
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 157
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 156
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 153
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 151
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 150
Oligomerization of ribonuclease A. Structural and functional features of its multimers 148
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 146
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 141
Protein Oligomerization 139
Platinated oligomers of bovine ribonuclease: Structure and stability 138
Oligomerization of ribonuclease A under reducing conditions 134
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 132
The two dimeric forms of RNase A 129
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 128
Structures of the two 3D domain-swapped RNase A trimers 126
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 120
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 118
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 118
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 118
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 112
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 111
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 107
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 106
Protein oligomerization 57
Onconase Induces Apoptosis in Dabrafenib-Resistant Melanoma Cell Lines Through Dysregulation of ROS Homeostasis, Antioxidant Protein Expression, and Mitochondrial Dynamics 29
Totale 10.208
Categoria #
all - tutte 34.361
article - articoli 30.973
book - libri 0
conference - conferenze 2.920
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 468
Totale 68.722


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022209 0 0 0 0 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/20251.273 73 88 60 211 66 28 52 51 217 85 116 226
2025/20264.093 291 301 362 650 987 251 325 183 328 227 107 81
2026/2027710 44 77 159 404 26 0 0 0 0 0 0 0
Totale 10.208