CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 1.897
EU - Europa 1.451
AS - Asia 751
SA - Sud America 7
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.111
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Nazione #
US - Stati Uniti d'America 1.892
CN - Cina 585
GB - Regno Unito 570
IT - Italia 159
SE - Svezia 145
FR - Francia 141
IE - Irlanda 137
FI - Finlandia 92
DE - Germania 85
SG - Singapore 56
RU - Federazione Russa 45
VN - Vietnam 45
UA - Ucraina 40
BE - Belgio 18
KR - Corea 16
TR - Turchia 12
IN - India 9
HK - Hong Kong 6
CA - Canada 5
TW - Taiwan 5
AU - Australia 4
CO - Colombia 4
ES - Italia 3
IR - Iran 3
NL - Olanda 3
AT - Austria 2
CL - Cile 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
IL - Israele 2
IQ - Iraq 2
JP - Giappone 2
PH - Filippine 2
PL - Polonia 2
SA - Arabia Saudita 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AZ - Azerbaigian 1
BR - Brasile 1
CH - Svizzera 1
HR - Croazia 1
KG - Kirghizistan 1
KW - Kuwait 1
LV - Lettonia 1
OM - Oman 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 4.111
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Città #
Southend 520
Chandler 377
Jacksonville 320
Woodbridge 228
Ann Arbor 175
Beijing 145
Dublin 137
Verona 77
Ashburn 74
Houston 70
Shenyang 58
Lawrence 56
Princeton 56
Jinan 54
Nanjing 53
Wilmington 48
New York 45
Hebei 34
Singapore 33
Dong Ket 32
Ningbo 27
Redmond 25
Tianjin 20
Changsha 18
Zhengzhou 18
Brussels 17
Haikou 16
Nanchang 16
Sindelfingen 16
Seattle 15
Taizhou 15
Helsinki 14
Boardman 13
Dearborn 13
Hangzhou 13
Taiyuan 11
Guangzhou 10
Seoul 10
Fuzhou 8
Jiaxing 8
Lanzhou 7
Norwalk 7
Tulsa 7
Redwood City 6
Bengaluru 5
Clearwater 5
Fairfield 5
Kemerovo 5
Kent 5
San Francisco 5
Bogotá 4
Bussolengo 4
Düsseldorf 4
Enterprise 4
Hong Kong 4
Lancaster 4
Milan 4
San Diego 4
Venice 4
Augusta 3
Bosco Chiesanuova 3
Buk-gu 3
Hearne 3
Los Angeles 3
Shanghai 3
Tappahannock 3
Yongin-si 3
Bologna 2
Boston 2
Brescia 2
College Station 2
Columbus 2
Dongguan 2
Evanston 2
Ferrara 2
Kochi 2
Leawood 2
Madrid 2
Melbourne 2
Napoli 2
Riva 2
Tainan City 2
Tarlac City 2
Toronto 2
Turin 2
Valkenburg 2
Vancouver 2
Vienna 2
Andover 1
Ardabil 1
Auburn Hills 1
Baku 1
Bedford 1
Berlin 1
Bishkek 1
Bratislava 1
Cambridge 1
Camerino 1
Canberra 1
Changle 1
Totale 3.066
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Nome #
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 114
Two different forms of aggregated dimers of ribonuclease A 112
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 110
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 105
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 98
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 98
Structural properties of trimers and tetramers of ribonuclease A 97
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 97
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 96
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 96
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 92
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 90
A domain-swapped RNase A dimer with implications for amyloid formation 88
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 87
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 85
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 84
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 82
Antitumor activity and other biological actions of oligomers of ribonuclease A 81
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 81
Oligomerization of ribonuclease A. Structural and functional features of its multimers 80
Some biological actions of PEG-conjugated RNase A oligomers 80
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 80
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 80
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 80
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 78
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 77
Investigations on onconase dimerization. 77
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 76
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 76
A novel biological actions acquired by ribonuclease through oligomerization 73
Human angiogenin dimerization and S28N pathogenic mutation. 72
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 71
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 70
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 69
Protein Oligomerization 69
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 66
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 65
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 65
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 65
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 64
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 64
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 63
Structures of the two 3D domain-swapped RNase A trimers 61
The two dimeric forms of RNase A 61
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 61
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 60
Oligomerization of ribonuclease A under reducing conditions 56
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 56
Platinated oligomers of bovine ribonuclease: Structure and stability 52
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 51
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 49
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 45
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 43
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 40
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 39
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 23
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 19
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 10
Protein oligomerization 6
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 5
Totale 4.190
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Categoria #
all - tutte 13.921
article - articoli 12.528
book - libri 0
conference - conferenze 1.192
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 201
Totale 27.842
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020636 67 7 3 46 42 66 66 55 29 80 59 116
2020/2021500 40 85 17 64 55 48 2 38 37 11 52 51
2021/2022464 44 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/202558 58 0 0 0 0 0 0 0 0 0 0 0
Totale 4.190