CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 2.808
EU - Europa 2.634
AS - Asia 1.951
SA - Sud America 274
AF - Africa 30
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 2
Totale 7.708
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Nazione #
US - Stati Uniti d'America 2.768
RU - Federazione Russa 1.017
CN - Cina 771
SG - Singapore 675
GB - Regno Unito 604
BR - Brasile 225
IT - Italia 184
HK - Hong Kong 167
SE - Svezia 158
FR - Francia 150
VN - Vietnam 138
IE - Irlanda 137
DE - Germania 131
FI - Finlandia 121
KR - Corea 62
UA - Ucraina 44
ID - Indonesia 27
CA - Canada 24
IN - India 22
BE - Belgio 19
PL - Polonia 19
TR - Turchia 17
AR - Argentina 14
NL - Olanda 11
BD - Bangladesh 10
CO - Colombia 10
VE - Venezuela 10
ES - Italia 9
IQ - Iraq 9
JP - Giappone 8
MX - Messico 8
ZA - Sudafrica 7
AT - Austria 6
AU - Australia 6
IL - Israele 6
MA - Marocco 6
TW - Taiwan 6
IR - Iran 5
TG - Togo 5
EC - Ecuador 4
EG - Egitto 4
LV - Lettonia 4
PK - Pakistan 4
CH - Svizzera 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
KG - Kirghizistan 3
PE - Perù 3
SA - Arabia Saudita 3
UY - Uruguay 3
UZ - Uzbekistan 3
AM - Armenia 2
AZ - Azerbaigian 2
BJ - Benin 2
BO - Bolivia 2
CL - Cile 2
DO - Repubblica Dominicana 2
HU - Ungheria 2
JM - Giamaica 2
KE - Kenya 2
PH - Filippine 2
SI - Slovenia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
BG - Bulgaria 1
DZ - Algeria 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HR - Croazia 1
HT - Haiti 1
IS - Islanda 1
KW - Kuwait 1
KZ - Kazakistan 1
LT - Lituania 1
MY - Malesia 1
NA - Namibia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PG - Papua Nuova Guinea 1
PS - Palestinian Territory 1
PY - Paraguay 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TJ - Tagikistan 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 7.708
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Città #
Southend 520
Dallas 383
Chandler 377
Moscow 326
Jacksonville 320
Singapore 258
Woodbridge 228
Ann Arbor 175
Beijing 173
Hong Kong 164
Ashburn 162
Dublin 137
Verona 79
New York 77
Houston 74
Shenyang 61
Lawrence 56
Princeton 56
Jinan 55
Nanjing 53
Wilmington 48
The Dalles 39
Munich 37
Ho Chi Minh City 36
Los Angeles 36
Columbus 35
Hebei 34
Dong Ket 32
Buffalo 27
Ningbo 27
Redmond 25
Hanoi 24
São Paulo 23
Tianjin 23
Helsinki 22
Council Bluffs 21
Jakarta 20
Changsha 19
Turku 19
Zhengzhou 19
Brussels 18
Seoul 18
Redondo Beach 17
Seattle 17
Haikou 16
Nanchang 16
Santa Clara 16
Sindelfingen 16
Taizhou 15
Warsaw 15
Hangzhou 14
San Francisco 14
Boardman 13
Dearborn 13
Guangzhou 13
Stockholm 13
London 11
Taiyuan 11
Boston 10
Brooklyn 10
Milan 9
Montreal 9
Fuzhou 8
Jiaxing 8
Brasília 7
Curitiba 7
Denver 7
Lanzhou 7
Norwalk 7
Tokyo 7
Tulsa 7
Manchester 6
Redwood City 6
Toronto 6
Amsterdam 5
Bengaluru 5
Bogotá 5
Clearwater 5
Fairfield 5
Johannesburg 5
Kemerovo 5
Kent 5
Lomé 5
Rio de Janeiro 5
Belo Horizonte 4
Brescia 4
Bussolengo 4
Chennai 4
Chicago 4
Da Nang 4
Düsseldorf 4
Enterprise 4
Frankfurt am Main 4
Lancaster 4
Mexico City 4
Riga 4
San Diego 4
Shijiazhuang 4
Vancouver 4
Venice 4
Totale 4.801
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Nome #
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 202
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 201
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 183
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 180
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 177
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 173
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 171
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 170
Antitumor activity and other biological actions of oligomers of ribonuclease A 164
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 163
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 159
Two different forms of aggregated dimers of ribonuclease A 158
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 156
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 155
Structural properties of trimers and tetramers of ribonuclease A 154
A domain-swapped RNase A dimer with implications for amyloid formation 153
Investigations on onconase dimerization. 152
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 149
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 148
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 147
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 147
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 142
A novel biological actions acquired by ribonuclease through oligomerization 142
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 138
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 135
Some biological actions of PEG-conjugated RNase A oligomers 134
Human angiogenin dimerization and S28N pathogenic mutation. 130
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 130
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 129
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 128
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 126
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 126
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 126
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 125
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 125
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 123
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 122
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 119
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 118
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 117
Oligomerization of ribonuclease A. Structural and functional features of its multimers 113
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 112
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 112
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 109
Structures of the two 3D domain-swapped RNase A trimers 106
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 102
The two dimeric forms of RNase A 102
Oligomerization of ribonuclease A under reducing conditions 102
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 100
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 96
Platinated oligomers of bovine ribonuclease: Structure and stability 96
Protein Oligomerization 95
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 87
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 87
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 82
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 80
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 78
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 78
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 59
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 56
Protein oligomerization 40
Totale 7.789
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Categoria #
all - tutte 26.112
article - articoli 23.534
book - libri 0
conference - conferenze 2.234
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 344
Totale 52.224
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021294 0 0 0 0 55 48 2 38 37 11 52 51
2021/2022464 44 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/20251.273 73 88 60 211 66 28 52 51 217 85 116 226
2025/20262.384 291 301 362 650 780 0 0 0 0 0 0 0
Totale 7.789