CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 2.886
EU - Europa 2.820
AS - Asia 2.095
SA - Sud America 285
AF - Africa 38
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.135
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Nazione #
US - Stati Uniti d'America 2.841
RU - Federazione Russa 1.199
CN - Cina 780
SG - Singapore 773
GB - Regno Unito 604
BR - Brasile 233
IT - Italia 184
HK - Hong Kong 168
VN - Vietnam 163
SE - Svezia 158
FR - Francia 150
IE - Irlanda 137
DE - Germania 131
FI - Finlandia 121
KR - Corea 63
UA - Ucraina 44
ID - Indonesia 28
CA - Canada 26
IN - India 22
PL - Polonia 20
BE - Belgio 19
TR - Turchia 17
AR - Argentina 15
VE - Venezuela 12
BD - Bangladesh 11
MX - Messico 11
NL - Olanda 11
CO - Colombia 10
IQ - Iraq 10
ES - Italia 9
ZA - Sudafrica 9
AT - Austria 8
JP - Giappone 8
MA - Marocco 8
AU - Australia 6
IL - Israele 6
TW - Taiwan 6
IR - Iran 5
TG - Togo 5
EC - Ecuador 4
EG - Egitto 4
KG - Kirghizistan 4
LV - Lettonia 4
PK - Pakistan 4
CH - Svizzera 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
KE - Kenya 3
PE - Perù 3
SA - Arabia Saudita 3
UY - Uruguay 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
AM - Armenia 2
AZ - Azerbaigian 2
BJ - Benin 2
BO - Bolivia 2
CL - Cile 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
HU - Ungheria 2
JM - Giamaica 2
ML - Mali 2
OM - Oman 2
PH - Filippine 2
PS - Palestinian Territory 2
SI - Slovenia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HR - Croazia 1
HT - Haiti 1
IS - Islanda 1
JO - Giordania 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
LB - Libano 1
LT - Lituania 1
MY - Malesia 1
NA - Namibia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PA - Panama 1
PG - Papua Nuova Guinea 1
PY - Paraguay 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TJ - Tagikistan 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 8.135
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Città #
Southend 520
Dallas 383
Moscow 383
Chandler 377
Singapore 355
Jacksonville 320
Woodbridge 228
Ashburn 195
Ann Arbor 175
Beijing 173
Hong Kong 165
Dublin 137
New York 79
Verona 79
Houston 74
Shenyang 61
The Dalles 60
Lawrence 56
Princeton 56
Jinan 55
Nanjing 53
Wilmington 48
Ho Chi Minh City 46
Los Angeles 37
Munich 37
Columbus 35
Hebei 34
Dong Ket 32
Hanoi 30
Buffalo 27
Ningbo 27
Redmond 25
São Paulo 24
Tianjin 24
Helsinki 22
Council Bluffs 21
Jakarta 20
Changsha 19
Turku 19
Zhengzhou 19
Brussels 18
Seattle 18
Seoul 18
Redondo Beach 17
Santa Clara 17
Haikou 16
Nanchang 16
Sindelfingen 16
Warsaw 16
Taizhou 15
Hangzhou 14
San Francisco 14
Boardman 13
Dearborn 13
Guangzhou 13
Stockholm 13
Boston 11
London 11
Montreal 11
Taiyuan 11
Brooklyn 10
Milan 9
Denver 8
Fuzhou 8
Jiaxing 8
Brasília 7
Curitiba 7
Johannesburg 7
Lanzhou 7
Norwalk 7
Tokyo 7
Tulsa 7
Manchester 6
Redwood City 6
Toronto 6
Amsterdam 5
Bengaluru 5
Bogotá 5
Chicago 5
Clearwater 5
Fairfield 5
Kemerovo 5
Kent 5
Lomé 5
Mexico City 5
Rio de Janeiro 5
San Jose 5
Vienna 5
Belo Horizonte 4
Bishkek 4
Brescia 4
Bussolengo 4
Caracas 4
Chennai 4
Da Nang 4
Düsseldorf 4
Enterprise 4
Frankfurt am Main 4
Lancaster 4
Orem 4
Totale 5.044
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Nome #
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 214
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 214
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 191
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 188
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 186
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 185
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 181
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 180
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 171
Antitumor activity and other biological actions of oligomers of ribonuclease A 171
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 167
Two different forms of aggregated dimers of ribonuclease A 164
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 162
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 161
Structural properties of trimers and tetramers of ribonuclease A 160
A domain-swapped RNase A dimer with implications for amyloid formation 159
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 159
Investigations on onconase dimerization. 159
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 155
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 154
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 152
A novel biological actions acquired by ribonuclease through oligomerization 149
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 148
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 147
Some biological actions of PEG-conjugated RNase A oligomers 141
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 139
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 138
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 138
Human angiogenin dimerization and S28N pathogenic mutation. 137
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 137
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 135
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 135
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 134
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 132
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 132
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 130
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 130
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 125
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 124
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 123
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 120
Oligomerization of ribonuclease A. Structural and functional features of its multimers 119
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 116
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 114
Structures of the two 3D domain-swapped RNase A trimers 108
Oligomerization of ribonuclease A under reducing conditions 108
The two dimeric forms of RNase A 107
Protein Oligomerization 107
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 105
Platinated oligomers of bovine ribonuclease: Structure and stability 105
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 104
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 99
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 92
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 91
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 87
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 85
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 84
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 81
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 67
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 66
Protein oligomerization 44
Totale 8.216
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Categoria #
all - tutte 26.995
article - articoli 24.317
book - libri 0
conference - conferenze 2.318
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 360
Totale 53.990
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021239 0 0 0 0 0 48 2 38 37 11 52 51
2021/2022464 44 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/20251.273 73 88 60 211 66 28 52 51 217 85 116 226
2025/20262.811 291 301 362 650 987 220 0 0 0 0 0 0
Totale 8.216