CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 3.707
EU - Europa 2.989
AS - Asia 2.442
SA - Sud America 321
Continente sconosciuto - Info sul continente non disponibili 84
AF - Africa 66
OC - Oceania 10
Totale 9.619
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Nazione #
US - Stati Uniti d'America 3.640
RU - Federazione Russa 1.200
SG - Singapore 890
CN - Cina 814
GB - Regno Unito 619
IT - Italia 289
BR - Brasile 254
VN - Vietnam 232
HK - Hong Kong 176
SE - Svezia 161
FR - Francia 154
DE - Germania 140
IE - Irlanda 139
FI - Finlandia 121
KR - Corea 80
BD - Bangladesh 52
UA - Ucraina 48
IN - India 43
CA - Canada 37
ID - Indonesia 29
PL - Polonia 26
BE - Belgio 19
IQ - Iraq 19
TR - Turchia 18
AR - Argentina 17
CO - Colombia 16
MX - Messico 15
ES - Italia 14
NL - Olanda 14
ZA - Sudafrica 14
JP - Giappone 13
MA - Marocco 13
NG - Nigeria 13
VE - Venezuela 12
AT - Austria 10
SA - Arabia Saudita 9
PK - Pakistan 8
AU - Australia 7
UZ - Uzbekistan 7
EC - Ecuador 6
IL - Israele 6
TW - Taiwan 6
EG - Egitto 5
IR - Iran 5
PH - Filippine 5
TG - Togo 5
BO - Bolivia 4
KE - Kenya 4
KG - Kirghizistan 4
LV - Lettonia 4
PE - Perù 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
CL - Cile 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
GR - Grecia 3
JM - Giamaica 3
JO - Giordania 3
MY - Malesia 3
AM - Armenia 2
AZ - Azerbaigian 2
BJ - Benin 2
BS - Bahamas 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
HN - Honduras 2
HR - Croazia 2
HU - Ungheria 2
ML - Mali 2
OM - Oman 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SI - Slovenia 2
TH - Thailandia 2
TN - Tunisia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HT - Haiti 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
LB - Libano 1
LT - Lituania 1
MD - Moldavia 1
MT - Malta 1
NA - Namibia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
Totale 9.528
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Città #
Southend 520
Singapore 460
Ashburn 384
Dallas 384
Moscow 383
Chandler 377
San Jose 338
Jacksonville 321
Woodbridge 228
Beijing 178
Ann Arbor 175
Hong Kong 173
Verona 145
Dublin 139
Council Bluffs 118
New York 87
The Dalles 87
Houston 76
Ho Chi Minh City 71
Shenyang 61
Lawrence 57
Princeton 56
Jinan 55
Los Angeles 55
Nanjing 53
Wilmington 48
Hanoi 47
Munich 37
Columbus 36
Hebei 34
Dong Ket 32
Buffalo 29
Santa Clara 29
São Paulo 29
Ningbo 27
Redmond 25
Tianjin 24
Helsinki 22
Jakarta 21
Warsaw 20
Zhengzhou 20
Changsha 19
Turku 19
Brussels 18
Seattle 18
Seoul 18
Redondo Beach 17
Haikou 16
Nanchang 16
San Francisco 16
Sindelfingen 16
Stockholm 15
Taizhou 15
Guangzhou 14
Hangzhou 14
London 14
Abuja 13
Boardman 13
Dearborn 13
Frankfurt am Main 13
Milan 13
Montreal 12
Boston 11
Brooklyn 11
Taiyuan 11
Johannesburg 10
Da Nang 9
Denver 9
Orem 9
Tokyo 9
Toronto 9
Amsterdam 8
Baghdad 8
Chennai 8
Chicago 8
Fuzhou 8
Jiaxing 8
Phoenix 8
Brasília 7
Curitiba 7
Lanzhou 7
Manchester 7
Norwalk 7
Tulsa 7
Bogotá 6
Mexico City 6
Redwood City 6
Rome 6
Tashkent 6
Vienna 6
Athens 5
Atlanta 5
Basingstoke 5
Belo Horizonte 5
Bengaluru 5
Brescia 5
Clearwater 5
Fairfield 5
Kemerovo 5
Kent 5
Totale 6.055
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Nome #
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 262
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 253
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 217
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 212
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 211
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 207
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 202
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 200
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 193
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 190
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 188
Antitumor activity and other biological actions of oligomers of ribonuclease A 187
Structural properties of trimers and tetramers of ribonuclease A 186
Investigations on onconase dimerization. 184
Two different forms of aggregated dimers of ribonuclease A 184
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 181
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 178
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 176
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 176
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 175
A domain-swapped RNase A dimer with implications for amyloid formation 173
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 171
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 170
A novel biological actions acquired by ribonuclease through oligomerization 168
Human angiogenin dimerization and S28N pathogenic mutation. 168
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 164
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 163
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 162
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 160
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 160
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 157
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 156
Some biological actions of PEG-conjugated RNase A oligomers 156
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 155
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 153
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 151
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 151
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 150
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 149
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 148
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 144
Oligomerization of ribonuclease A. Structural and functional features of its multimers 140
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 140
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 139
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 133
Platinated oligomers of bovine ribonuclease: Structure and stability 132
Oligomerization of ribonuclease A under reducing conditions 128
Protein Oligomerization 126
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 123
The two dimeric forms of RNase A 123
Structures of the two 3D domain-swapped RNase A trimers 119
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 117
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 114
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 110
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 110
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 107
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 102
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 102
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 100
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 91
Protein oligomerization 52
Onconase Induces Apoptosis in Dabrafenib-Resistant Melanoma Cell Lines Through Dysregulation of ROS Homeostasis, Antioxidant Protein Expression, and Mitochondrial Dynamics 20
Totale 9.619
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Categoria #
all - tutte 32.344
article - articoli 29.178
book - libri 0
conference - conferenze 2.735
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 431
Totale 64.688
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022420 0 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/20251.273 73 88 60 211 66 28 52 51 217 85 116 226
2025/20264.093 291 301 362 650 987 251 325 183 328 227 107 81
2026/2027121 44 77 0 0 0 0 0 0 0 0 0 0
Totale 9.619