CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 3.489
EU - Europa 2.950
AS - Asia 2.391
SA - Sud America 312
AF - Africa 66
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.220
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Nazione #
US - Stati Uniti d'America 3.434
RU - Federazione Russa 1.200
SG - Singapore 883
CN - Cina 808
GB - Regno Unito 618
IT - Italia 259
BR - Brasile 250
VN - Vietnam 232
HK - Hong Kong 175
SE - Svezia 161
FR - Francia 153
DE - Germania 140
IE - Irlanda 139
FI - Finlandia 121
KR - Corea 80
UA - Ucraina 48
IN - India 42
CA - Canada 30
ID - Indonesia 29
PL - Polonia 23
BE - Belgio 19
IQ - Iraq 19
BD - Bangladesh 18
TR - Turchia 18
AR - Argentina 17
CO - Colombia 14
MX - Messico 14
NL - Olanda 14
ZA - Sudafrica 14
MA - Marocco 13
NG - Nigeria 13
ES - Italia 12
JP - Giappone 12
VE - Venezuela 12
AT - Austria 10
SA - Arabia Saudita 9
PK - Pakistan 8
AU - Australia 7
UZ - Uzbekistan 7
IL - Israele 6
TW - Taiwan 6
EC - Ecuador 5
EG - Egitto 5
IR - Iran 5
TG - Togo 5
BO - Bolivia 4
KE - Kenya 4
KG - Kirghizistan 4
LV - Lettonia 4
PH - Filippine 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
GR - Grecia 3
JO - Giordania 3
MY - Malesia 3
PE - Perù 3
AM - Armenia 2
AZ - Azerbaigian 2
BJ - Benin 2
CL - Cile 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
HR - Croazia 2
HU - Ungheria 2
JM - Giamaica 2
ML - Mali 2
OM - Oman 2
PS - Palestinian Territory 2
RS - Serbia 2
SI - Slovenia 2
TH - Thailandia 2
TN - Tunisia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HN - Honduras 1
HT - Haiti 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
LB - Libano 1
LT - Lituania 1
MT - Malta 1
NA - Namibia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PA - Panama 1
PG - Papua Nuova Guinea 1
PT - Portogallo 1
Totale 9.213
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Città #
Southend 520
Singapore 456
Dallas 384
Moscow 383
Chandler 377
Ashburn 365
San Jose 327
Jacksonville 320
Woodbridge 228
Ann Arbor 175
Beijing 174
Hong Kong 172
Verona 145
Dublin 139
The Dalles 87
New York 81
Houston 74
Ho Chi Minh City 71
Shenyang 61
Lawrence 56
Princeton 56
Jinan 55
Nanjing 53
Wilmington 48
Hanoi 47
Los Angeles 44
Munich 37
Columbus 36
Hebei 34
Dong Ket 32
Council Bluffs 28
São Paulo 28
Buffalo 27
Ningbo 27
Redmond 25
Tianjin 24
Helsinki 22
Jakarta 21
Santa Clara 20
Zhengzhou 20
Changsha 19
Turku 19
Brussels 18
Seattle 18
Seoul 18
Warsaw 18
Redondo Beach 17
Haikou 16
Nanchang 16
San Francisco 16
Sindelfingen 16
Stockholm 15
Taizhou 15
Guangzhou 14
Hangzhou 14
London 14
Abuja 13
Boardman 13
Dearborn 13
Frankfurt am Main 13
Montreal 12
Boston 11
Brooklyn 11
Taiyuan 11
Johannesburg 10
Milan 10
Da Nang 9
Orem 9
Tokyo 9
Amsterdam 8
Baghdad 8
Chennai 8
Denver 8
Fuzhou 8
Jiaxing 8
Brasília 7
Curitiba 7
Lanzhou 7
Manchester 7
Norwalk 7
Tulsa 7
Chicago 6
Redwood City 6
Tashkent 6
Toronto 6
Vienna 6
Atlanta 5
Basingstoke 5
Bengaluru 5
Bogotá 5
Clearwater 5
Fairfield 5
Kemerovo 5
Kent 5
Lomé 5
Mexico City 5
Porto Alegre 5
Rio de Janeiro 5
Athens 4
Augusta 4
Totale 5.874
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Nome #
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 245
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 239
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 214
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 206
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 205
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 204
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 197
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 197
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 191
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 186
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 186
Antitumor activity and other biological actions of oligomers of ribonuclease A 185
Structural properties of trimers and tetramers of ribonuclease A 180
Investigations on onconase dimerization. 179
Two different forms of aggregated dimers of ribonuclease A 176
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 175
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 174
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 173
A domain-swapped RNase A dimer with implications for amyloid formation 171
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 171
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 169
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 169
Human angiogenin dimerization and S28N pathogenic mutation. 166
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 164
A novel biological actions acquired by ribonuclease through oligomerization 163
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 158
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 158
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 156
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 155
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 154
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 153
Some biological actions of PEG-conjugated RNase A oligomers 153
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 151
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 150
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 147
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 147
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 147
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 146
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 145
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 139
Oligomerization of ribonuclease A. Structural and functional features of its multimers 138
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 138
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 137
Platinated oligomers of bovine ribonuclease: Structure and stability 129
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 128
The two dimeric forms of RNase A 121
Protein Oligomerization 121
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 120
Oligomerization of ribonuclease A under reducing conditions 120
Structures of the two 3D domain-swapped RNase A trimers 116
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 114
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 114
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 110
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 108
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 104
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 102
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 99
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 96
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 90
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 87
Protein oligomerization 52
Onconase Induces Apoptosis in Dabrafenib-Resistant Melanoma Cell Lines Through Dysregulation of ROS Homeostasis, Antioxidant Protein Expression, and Mitochondrial Dynamics 14
Totale 9.302
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Categoria #
all - tutte 29.139
article - articoli 26.229
book - libri 0
conference - conferenze 2.525
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 385
Totale 58.278
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021114 0 0 0 0 0 0 0 0 0 11 52 51
2021/2022464 44 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/20251.273 73 88 60 211 66 28 52 51 217 85 116 226
2025/20263.897 291 301 362 650 987 251 325 183 328 219 0 0
Totale 9.302