CATALOGO DEI PRODOTTI DELLA RICERCA

GOTTE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 2.569
EU - Europa 1.710
AS - Asia 1.657
SA - Sud America 192
AF - Africa 23
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.162
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Nazione #
US - Stati Uniti d'America 2.543
CN - Cina 690
GB - Regno Unito 591
SG - Singapore 573
IT - Italia 172
BR - Brasile 163
HK - Hong Kong 162
SE - Svezia 154
FR - Francia 149
IE - Irlanda 137
RU - Federazione Russa 137
DE - Germania 128
FI - Finlandia 121
VN - Vietnam 69
KR - Corea 53
UA - Ucraina 44
ID - Indonesia 21
BE - Belgio 19
IN - India 19
TR - Turchia 17
CA - Canada 14
PL - Polonia 14
NL - Olanda 9
CO - Colombia 8
IQ - Iraq 7
AT - Austria 6
AU - Australia 6
BD - Bangladesh 6
ES - Italia 6
IL - Israele 6
TW - Taiwan 6
VE - Venezuela 6
ZA - Sudafrica 6
MX - Messico 5
TG - Togo 5
AR - Argentina 4
EG - Egitto 4
IR - Iran 4
JP - Giappone 4
LV - Lettonia 4
CH - Svizzera 3
CZ - Repubblica Ceca 3
DK - Danimarca 3
EC - Ecuador 3
SA - Arabia Saudita 3
AM - Armenia 2
AZ - Azerbaigian 2
CL - Cile 2
HU - Ungheria 2
JM - Giamaica 2
KE - Kenya 2
KG - Kirghizistan 2
MA - Marocco 2
PE - Perù 2
PH - Filippine 2
PK - Pakistan 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
BO - Bolivia 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GT - Guatemala 1
HR - Croazia 1
HT - Haiti 1
IS - Islanda 1
KW - Kuwait 1
LT - Lituania 1
MY - Malesia 1
NA - Namibia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PG - Papua Nuova Guinea 1
PY - Paraguay 1
RO - Romania 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TJ - Tagikistan 1
TN - Tunisia 1
UZ - Uzbekistan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 6.162
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Città #
Southend 520
Chandler 377
Dallas 327
Jacksonville 320
Singapore 255
Woodbridge 228
Ann Arbor 175
Hong Kong 160
Beijing 155
Dublin 137
Ashburn 94
Verona 77
Houston 71
New York 61
Shenyang 59
Lawrence 56
Princeton 56
Jinan 54
Nanjing 53
Wilmington 48
The Dalles 38
Munich 37
Columbus 35
Hebei 34
Dong Ket 32
Ningbo 27
Redmond 25
Helsinki 22
Los Angeles 21
Tianjin 21
Buffalo 20
Changsha 19
Jakarta 19
Turku 19
Zhengzhou 19
Brussels 18
Council Bluffs 17
Seattle 17
Haikou 16
Nanchang 16
Sindelfingen 16
São Paulo 15
Taizhou 15
Hangzhou 14
Santa Clara 14
Boardman 13
Dearborn 13
San Francisco 13
Seoul 13
Guangzhou 12
Ho Chi Minh City 12
Taiyuan 11
Warsaw 11
Stockholm 9
Boston 8
Brooklyn 8
Fuzhou 8
Jiaxing 8
Milan 8
Redondo Beach 8
Lanzhou 7
Norwalk 7
Tulsa 7
Redwood City 6
Bengaluru 5
Bogotá 5
Brasília 5
Clearwater 5
Denver 5
Fairfield 5
Johannesburg 5
Kemerovo 5
Kent 5
Lomé 5
Rio de Janeiro 5
Brescia 4
Bussolengo 4
Chicago 4
Curitiba 4
Düsseldorf 4
Enterprise 4
Frankfurt am Main 4
Lancaster 4
London 4
Manchester 4
Montreal 4
Riga 4
San Diego 4
Toronto 4
Venice 4
Vienna 4
Amsterdam 3
Augusta 3
Belo Horizonte 3
Bosco Chiesanuova 3
Buk-gu 3
Chennai 3
Dongguan 3
Hanoi 3
Hearne 3
Totale 4.157
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Nome #
Onconase cytotoxicity in melanoma cancer cells: promising results to be enforced by oligomerizing the protein 164
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 160
Two different forms of aggregated dimers of ribonuclease A 148
Antitumor effect of Onconase in A375 melanoma cell line. A proteomic analysis. 144
Degenerative action on mice and rat testes of polyspermine and itscomplexes with RNase A 142
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action 138
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 138
Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach 138
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 136
Structural properties of trimers and tetramers of ribonuclease A 134
A domain-swapped RNase A dimer with implications for amyloid formation 129
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 128
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 126
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 122
Antitumor activity and other biological actions of oligomers of ribonuclease A 122
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 119
"Zero-Length" Dimers of Ribonuclease A: Further Characterization and No Evidence of Cytotoxicity 118
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs 118
Investigations on onconase dimerization. 117
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor 116
Short-time non-enzymatic nitric oxide synthase from L-arginine and hydrogen peroxide induced by shock waves treatment 116
A novel biological actions acquired by ribonuclease through oligomerization 115
Carbodiimide EDC Induces Cross-Links That Stabilize RNase A C-dimer against Dissociation: EDC Adducts Can Affect Protein Net Charge, Conformation, and Activity 115
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 115
Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function 114
Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer 113
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure. 113
Some biological actions of PEG-conjugated RNase A oligomers 110
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 108
Oligomerization of ribonuclease A. Structural and functional features of its multimers 107
Thermal Aggregation of Ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation 106
Human angiogenin dimerization and S28N pathogenic mutation. 101
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping 100
Elucidation of the Ribonuclease A Aggregation Process Mediated by 3D Domain Swapping: A Computational Approach Reveals Possible New Multimeric Structures 99
Properties of RNase A monomer and dimers depend on the oligomerization pathway followed. 97
RNase A domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity 97
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 96
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability 95
Oligomerization of ribonuclease A under reducing conditions 94
RNase A oligomerization through 3D domain swapping is favouredby a residue located far from the swapping domains 94
Three-dimensional domain-swapped oligomers of ribonuclease A: Identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species 92
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells 92
Structures of the two 3D domain-swapped RNase A trimers 91
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases 91
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers 88
Oligomerization of ribonuclease A. Two novel three-dimensional domain-swapped tetramers 87
Protein Oligomerization 84
NMR characterization of angiogenin variants and tRNAAla products impacting aberrant protein oligomerization 84
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme 84
The two dimeric forms of RNase A 83
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins 78
Structural versatility of BS-RNase: Different oligomeric isomers formed through 3D domain swapping of N- and C-termini 74
Platinated oligomers of bovine ribonuclease: Structure and stability 73
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation 68
Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs 66
Slow evolution toward "Super-Aggregation" of the oligomers formed through the swapping of RNase A N-Termini: a wish for amyloidosis? 53
Effects of pathogenic mutants of the neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS) 49
Role of the Ribonuclease ONCONASE in miRNA Biogenesis and tRNA Processing: Focus on Cancer and Viral Infections 44
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 36
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus 34
Protein oligomerization 30
Totale 6.243
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Categoria #
all - tutte 23.043
article - articoli 20.773
book - libri 0
conference - conferenze 1.957
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 313
Totale 46.086
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021375 0 0 17 64 55 48 2 38 37 11 52 51
2021/2022464 44 173 20 18 10 8 6 32 13 12 35 93
2022/20231.012 63 128 87 198 74 237 7 62 104 8 25 19
2023/2024422 23 33 32 46 45 69 8 45 2 23 66 30
2024/20251.273 73 88 60 211 66 28 52 51 217 85 116 226
2025/2026838 291 301 246 0 0 0 0 0 0 0 0 0
Totale 6.243