DONADELLI, Massimo
 Distribuzione geografica
Continente #
NA - Nord America 3.395
EU - Europa 3.144
AS - Asia 1.557
SA - Sud America 17
AF - Africa 11
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.133
Nazione #
US - Stati Uniti d'America 3.372
GB - Regno Unito 1.154
CN - Cina 910
IT - Italia 477
SG - Singapore 391
FR - Francia 269
SE - Svezia 264
RU - Federazione Russa 240
IE - Irlanda 237
DE - Germania 195
FI - Finlandia 151
VN - Vietnam 85
UA - Ucraina 61
TR - Turchia 39
BE - Belgio 35
ID - Indonesia 35
KR - Corea 27
CA - Canada 22
JP - Giappone 16
NL - Olanda 16
ES - Italia 15
IN - India 14
IR - Iran 14
TG - Togo 9
AU - Australia 7
BR - Brasile 6
SA - Arabia Saudita 6
CL - Cile 5
PL - Polonia 5
HK - Hong Kong 4
CH - Svizzera 3
MM - Myanmar 3
RO - Romania 3
AL - Albania 2
BO - Bolivia 2
CO - Colombia 2
DK - Danimarca 2
IL - Israele 2
KG - Kirghizistan 2
MY - Malesia 2
NO - Norvegia 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
AT - Austria 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BY - Bielorussia 1
CZ - Repubblica Ceca 1
EC - Ecuador 1
EE - Estonia 1
EG - Egitto 1
EU - Europa 1
GE - Georgia 1
GR - Grecia 1
HR - Croazia 1
HU - Ungheria 1
IQ - Iraq 1
KW - Kuwait 1
LU - Lussemburgo 1
MD - Moldavia 1
MX - Messico 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PE - Perù 1
PK - Pakistan 1
PT - Portogallo 1
TH - Thailandia 1
Totale 8.133
Città #
Southend 1.082
Chandler 676
Jacksonville 360
Singapore 331
Woodbridge 328
Ann Arbor 301
Dublin 235
Verona 200
Beijing 168
Ashburn 155
New York 147
Houston 141
Lawrence 93
Princeton 93
Wilmington 89
Nanjing 74
Jinan 70
Redmond 70
Shenyang 61
Hebei 48
Dong Ket 45
Helsinki 44
Phoenix 44
Tianjin 42
Jakarta 34
Redwood City 34
Changsha 33
Sindelfingen 33
Brussels 32
Haikou 30
Venice 30
Zhengzhou 30
Nanchang 28
Seoul 26
Düsseldorf 24
Ningbo 22
Boardman 21
Dallas 21
Norwalk 21
Hangzhou 20
Jiaxing 20
Kent 17
Seattle 17
Guangzhou 16
Taizhou 16
Milan 15
Munich 15
Taiyuan 13
Caserta 12
Augusta 11
Tokyo 11
Washington 11
Fuzhou 10
Toronto 10
Auburn Hills 9
Falls Church 9
Lomé 9
Madrid 9
Santa Clara 9
San Francisco 8
Bologna 7
Dearborn 7
Los Angeles 7
Mestre 7
Ardabil 6
Lanzhou 6
Lappeenranta 6
San Mateo 6
Chions 5
Clearwater 5
Fairfield 5
Leawood 5
London 5
Monmouth Junction 5
Montréal 5
Moscow 5
Mumbai 5
Riyadh 5
San Giovanni Ilarione 5
Cambridge 4
Chicago 4
Cleveland 4
San Diego 4
Shanghai 4
Amsterdam 3
Boydton 3
Can Tho 3
Edinburgh 3
Elora 3
Ghent 3
Groningen 3
Hanoi 3
Hong Kong 3
Kemerovo 3
Nürnberg 3
Poggio Rusco 3
Qingdao 3
Rome 3
San Jose 3
Sapporo 3
Totale 5.758
Nome #
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism 224
Gemcitabine response in pancreatic adenocarcinoma cells is synergistically enhanced by dithiocarbamate derivatives 165
Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells. 140
ISOLATION AND DRUG SENSITIVITY OF CANCER STEM CELLS OBTAINED FROM PANCREATIC ADENOCARCINOMA CELL LINES 140
Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival 140
UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells 132
Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis. 128
Role of mitochondrial uncoupling protein-2 in cancer cell resistance to gemcitabine 126
Activation of the Interleukin-6 promoter by a dominant negative mutant of c-Jun 124
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 123
Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kappaB and JNK/AP-1 pathways 121
REDOX SIGNALING HYPERSENSITIVITY DISTINGUISHES CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS WITH FAVORABLE PROGNOSIS 120
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition 119
Cytotoxicity of Polyspermine-Ribonuclease A and Polyspermine-Dimeric Ribonuclease A 118
HUMAN T-LYMPHOBLASTIC LEUKAEMIA CELLS PRODUCE IL-8 IN RESPONSE TOCXCL12 SECRETED BY NORMAL BONE MARROW STROMA 114
Comparative proteomic and phosphoproteomic profiling of pancreatic adenocarcinoma cells treated with CB1 or CB2 agonists 112
Regulation of miR-23b expression and its dual role on ROS production and tumour development 111
Biopsychosocial model of resilience in young adults with multiple sclerosis (BPS-ARMS): an observational study protocol exploring psychological reactions early after diagnosis 111
Hyaluronic acid-coated liposomes for active targeting of gemcitabine 111
Pancreatic endocrine tumours, a proteomic investigation of the trichostatin-A antitumoral effect 110
Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine 108
Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells 108
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells 107
CXCL12-MEDIATED NF-KAPPAB AND C-JUN ACTIVATION REGULATES INTERLEUKIN 8 PRODUCTION IN HUMAN T-LYMPHOBLASTIC LEUKEMIA 105
Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells 105
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner 104
Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation. 102
Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene 102
Proteomics in pancreatic cancer research. 101
Intracellular zinc increase inhibits p53(-/-) pancreatic adenocarcinoma cell growth by ROS/AIF-mediated apoptosis 99
Increase of RNase A N-terminus Polarity or C-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein 97
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 97
Zinc depletion efficiently inhibits pancreatic cancer cell growth by increasing the ratio of antiproliferative/proliferative genes. 93
Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities 92
Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway 91
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines 89
Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine 89
The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition 89
Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine 88
The metabolic landscape of cancer stem cells 87
Regulation of catalase expression in chronic lymphocytic leukemia cells. 87
UCP2, a mitochondrial protein regulated at multiple levels 84
Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells 84
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy 83
UCP2 inhibition induces ROS/Akt/mTOR axis: role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 82
Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A 81
Low catalase expression confers redox hypersensitivity and identifies an indolent clinical behavior in CLL 81
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells 81
Targeting survival signaling pathways in chronic lymphocytic leukemia via anti-CD20 antibodies 81
Mutant p53 and mTOR/PKM2 regulation in cancer cells 78
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells 78
Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity 77
Mitochondrial uncoupling protein-2 inhibition promotes gemcitabine response in cancer cells. 77
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis 76
Effects of CD20 antibodies and kinase inhibitors on B-cell receptor signalling and survival of chronic lymphocytic leukaemia cells 75
The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia 74
“Proteomic profiling of pancreatic ductal carcinoma cell lines treated with trichostatin-A” 74
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 74
Regulation of autophagy by nuclear GAPDH and its aggregates in cancer and neurodegenerative disorders 73
Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. 72
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study 72
Oncometabolites in cancer aggressiveness and tumour repopulation 72
Molecular interplay between mutant p53 proteins and autophagy in cancer cells 71
Rehabilitation and biomarkers of stroke recovery: study protocol for a randomized controlled trial 71
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin 70
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine 69
Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer 69
Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A. 68
Mitochondrial uncoupling protein 2 and pancreatic cancer: a new potential target therapy 68
Autocrine mechanisms of cancer chemoresistance 66
Cell communication and signaling: how to turn bad language into positive one 66
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells 59
Roles for microRNA 23b in regulating autophagy and development of pancreatic adenocarcinoma 58
ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma 58
The cancer secretome and secreted biomarkers 57
Interplay between ROS and Autophagy in Cancer and Aging: From Molecular Mechanisms to Novel Therapeutic Approaches 57
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC 56
Sestrins at the Interface of ROS Control and Autophagy Regulation in Health and Disease 55
The mutant p53-driven secretome has oncogenic functions in pancreatic ductal adenocarcinoma cells 55
Gut microbiota modulates seizure susceptibility 55
Proteomic Signature of PDAC Cells with Mutant p53 52
Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis 50
MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells 49
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 48
Redox sensitive cysteine residues as crucial regulators of wild-type and mutant p53 isoforms 47
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 45
Reprogramming tumor-immune cell interface in solid and hematological malignancies to enhance response to therapy 45
Regulation of succinate dehydrogenase and role of succinate in cancer 45
Sestrins as a therapeutic bridge between ROS and autophagy in cancer 45
From single gene analysis to single cell profiling: a new era for precision medicine 42
Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons 39
B-cell receptor signaling activity identifies patients with mantle cell lymphoma at higher risk of progression 37
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer 37
miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma 36
Hypoxia dictates metabolic rewiring of tumors: implications for chemoresistance 35
Mitochondrial metabolic alterations in cancer cells and related therapeutic targets 32
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism 26
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 25
Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells 24
Bone marrow stromal cells up-regulate interleukin 8 production in human T-lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-κB and JNK/AP-1 pathways 21
Totale 8.166
Categoria #
all - tutte 30.005
article - articoli 27.440
book - libri 0
conference - conferenze 2.565
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.010


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020605 0 0 0 0 99 95 87 46 58 93 41 86
2020/2021893 130 105 40 79 103 90 33 49 45 10 106 103
2021/2022815 114 200 20 53 21 19 26 52 25 29 71 185
2022/20231.867 121 196 154 364 158 418 23 98 206 61 50 18
2023/2024940 37 56 74 92 116 217 29 78 15 48 132 46
2024/2025863 112 153 90 398 110 0 0 0 0 0 0 0
Totale 8.276