Mitochondrial anion transporter proteins localized into the mitochondrial inner membrane. Currently, five UCP family members have been identified in mammals.Among them, UCP2 is widely distributedthroughout the organism, suggesting different and wide functions for this mitochondrial uncoupling protein. Basically, the antioxidant role of UCP2 is due to its capability to decrease the mitochondrial potential and to dissipate the proton gradient.
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy
CORDANI, MARCO;BUTERA, GIOVANNA;PACCHIANA, Raffaella;DONADELLI, Massimo
2017-01-01
Abstract
Mitochondrial anion transporter proteins localized into the mitochondrial inner membrane. Currently, five UCP family members have been identified in mammals.Among them, UCP2 is widely distributedthroughout the organism, suggesting different and wide functions for this mitochondrial uncoupling protein. Basically, the antioxidant role of UCP2 is due to its capability to decrease the mitochondrial potential and to dissipate the proton gradient.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
6451-28729-2-PB.pdf
accesso aperto
Descrizione: CC-BY-NC 4.0 publisher version
Tipologia:
Versione dell'editore
Licenza:
Creative commons
Dimensione
544.95 kB
Formato
Adobe PDF
|
544.95 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
