CATALOGO DEI PRODOTTI DELLA RICERCA

BERTOLDI, Mariarita
 Distribuzione geografica
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Continente #
NA - Nord America 3.183
EU - Europa 3.053
AS - Asia 2.548
SA - Sud America 376
AF - Africa 39
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.208
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Nazione #
US - Stati Uniti d'America 3.133
GB - Regno Unito 1.017
CN - Cina 978
SG - Singapore 943
RU - Federazione Russa 707
BR - Brasile 325
HK - Hong Kong 282
IT - Italia 248
FR - Francia 207
FI - Finlandia 197
DE - Germania 188
SE - Svezia 167
IE - Irlanda 149
VN - Vietnam 95
KR - Corea 83
UA - Ucraina 56
CA - Canada 36
ID - Indonesia 30
JP - Giappone 28
IN - India 26
NL - Olanda 20
AR - Argentina 18
AT - Austria 18
BD - Bangladesh 18
TR - Turchia 18
BE - Belgio 17
ES - Italia 16
TG - Togo 15
PL - Polonia 13
EC - Ecuador 9
LT - Lituania 9
MX - Messico 9
ZA - Sudafrica 8
CL - Cile 7
IL - Israele 6
IQ - Iraq 6
MA - Marocco 6
UZ - Uzbekistan 6
AE - Emirati Arabi Uniti 5
JO - Giordania 5
SA - Arabia Saudita 5
AU - Australia 4
BG - Bulgaria 4
BO - Bolivia 4
RO - Romania 4
SK - Slovacchia (Repubblica Slovacca) 4
UY - Uruguay 4
CH - Svizzera 3
CO - Colombia 3
PK - Pakistan 3
DK - Danimarca 2
EG - Egitto 2
GE - Georgia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PA - Panama 2
PY - Paraguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EU - Europa 1
GF - Guiana Francese 1
GR - Grecia 1
GY - Guiana 1
HR - Croazia 1
HU - Ungheria 1
KE - Kenya 1
KG - Kirghizistan 1
KH - Cambogia 1
MU - Mauritius 1
NO - Norvegia 1
OM - Oman 1
PE - Perù 1
PG - Papua Nuova Guinea 1
PS - Palestinian Territory 1
RW - Ruanda 1
SI - Slovenia 1
SV - El Salvador 1
TH - Thailandia 1
TN - Tunisia 1
VE - Venezuela 1
ZW - Zimbabwe 1
Totale 9.208
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Città #
Southend 924
Jacksonville 405
Singapore 405
Dallas 401
Chandler 313
Hong Kong 280
Woodbridge 226
Ann Arbor 198
Ashburn 198
Houston 191
Beijing 171
Moscow 157
Dublin 149
Verona 121
Jinan 102
Shenyang 74
Wilmington 73
Lawrence 69
Princeton 69
Nanjing 62
Helsinki 61
Los Angeles 58
New York 50
Hebei 44
Munich 43
Buffalo 42
The Dalles 40
Columbus 39
Changsha 36
Zhengzhou 32
Ningbo 31
São Paulo 30
Tianjin 29
Jakarta 27
London 27
Redondo Beach 26
Tokyo 26
Milan 22
Falls Church 21
Haikou 21
Chicago 20
Hangzhou 20
Ho Chi Minh City 19
Sindelfingen 19
Guangzhou 18
Taiyuan 18
Lappeenranta 17
Nanchang 17
Seattle 17
Brussels 16
Redmond 16
Santa Clara 16
Taizhou 16
Frankfurt am Main 15
Lomé 15
Turku 15
Council Bluffs 14
Dong Ket 14
Lancaster 14
Nuremberg 14
Jiaxing 13
Lanzhou 13
Norwalk 13
Fuzhou 12
Rome 12
Montreal 11
San Francisco 11
Seoul 11
Toronto 11
Warsaw 11
Brooklyn 10
Rio de Janeiro 10
Amsterdam 9
Boardman 9
Denver 9
Hanoi 9
Phoenix 9
Vienna 9
Chennai 8
Kent 8
Shanghai 8
Brasília 7
Fairfield 7
Renton 7
Belo Horizonte 6
Boston 6
Campinas 6
Elora 6
Falkenstein 6
Padova 6
Redwood City 6
Riva 6
Stockholm 6
Amman 5
Berlin 5
Bologna 5
Clearwater 5
Curitiba 5
Hải Dương 5
Istanbul 5
Totale 5.949
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Nome #
Dimerization and Folding Processes of Treponema denticola Cystalysin: The Role of Pyridoxal 5'-Phosphate 214
Holo-and apocystalysin from Treponema denticola: two different conformations 206
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 188
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 167
The novel R347g pathogenic mutation Of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency 162
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis 158
Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice 154
Dopa decarboxylase exhibits low pH half-transaminase and high pH oxidative deaminase activities toward serotonin (5-hydroxytryptamine) 152
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 148
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 146
Structural properties of trimers and tetramers of ribonuclease A 145
Pathogenic variants of human Aromatic L-Amino Acid Decarboxylase: evidences of misfolding in functionally active variants 145
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 144
Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii 142
Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band3 137
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 134
Oxidative stress and b-thalasssemic erythroid cells behind the molecular defect 134
Oxidative stress modulates heme levels and induces peroxiredoxin-2 in β thalassemic erythropoiesis as novel cytoprotective response 133
Mutation of residues in the coenzyme binding pocket of Dopa decarboxylase: effects on catalytic properties 132
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase 130
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity 130
Phosphorylation of pyridoxal 5'-phosphate enzymes: an intriguing and neglected topic 127
Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase 126
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 125
New insights emerging from recent investigations on human group II pyridoxal 5'-phosphate Decarboxylases 125
Dopa decarboxylase 124
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice 123
New variants of AADC deficiency expand the knowledge of enzymatic phenotypes 120
Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease 119
Cysteine 180 Is a Redox Sensor Modulating the Activity of Human Pyridoxal 5'-Phosphate Histidine Decarboxylase 119
Aromatic amino acid decarboxylase deficiency: Molecular and metabolic basis and therapeutic outlook 117
Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease 116
Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis 115
The novel role of peroxiredoxin-2 in red cell membrane protein homeostasis and senescence. 113
Insights into the mechanism of oxidative deamination catalyzed by Dopa decarboxylase 112
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 111
Compound heterozygosis in AADC deficiency: A complex phenotype dissected through comparison among heterodimeric and homodimeric AADC proteins 111
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 109
Oxygen reactivity with pyridoxal 5'-phosphate enzymes: biochemical implications and functional relevance 109
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 106
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 106
Dopa decarboxylase 105
Tyrosine phosphorylation modulates peroxiredoxin-2 activity in normal and diseased red cells 102
Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations 101
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their alpha-methyl substrates 100
Mutation of cysteine 111 in dopa decarboxylase leads to active site perturbation 100
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 99
Parkinson's Disease: recent updates in the identification of human dopa decarboxylase inhibitors 99
Peroxiredoxin-2 (Prx2) expression is increased in beta thalassemic mouse red cells but displaced from the membrane as marker of oxidative stress 98
Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis? 98
Mechanism-based inactivation of dopa decarboxylase by serotonin 97
Reaction specificity of native and nicked 3,4-dihydroxyphenylalanine decarboxylase 97
Reaction of Dopa decarboxylase with alfa-methylDopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active-site directed affinity label 95
A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies 95
The activity on double-stranded RNA of aggregates of Ribonuclease A higher than dimers increases as a function of the size of the aggregates 94
Mutation of tyrosine 332 to phenylalanine converts Dopa decarboxylase into a decarboxylation-dependent oxidative deaminase 92
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 92
Aromatic l-amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies 90
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 89
Human peroxiredoxins 1 and 2 and their interacting protein partners; through structure toward functions of biological complexes 87
Mapping of human autoantibody epitopes on aromatic l-amino acid decarboxylase 85
Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: Could such a scenario be helpful to counteract COVID-19? 83
Structural insights into the heme pocket and oligomeric state of non-symbiotic hemoglobins from Arabidopsis thaliana 82
Multiple roles of the active site lysine of Dopa decarboxylase 78
Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: implication in AADC deficiency 77
Reaction and substrate specificity of pig kidney Dopa decarboxylase under aerobic and anaerobic conditions 77
The novel P330L pathogenic variant of aromatic amino acid decarboxylase maps on the catalytic flexible loop underlying its crucial role 75
Mammalian Dopa decarboxylase: structure, catalytic activity and inhibition 70
Compound heterozygosis in AADC deficiency and its complex phenotype in terms of AADC protein population 69
Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency 67
Human DOPA decarboxylase: catalysis and involvement in pharmacologica treatments of Parkinson's disease and aromatic amino acid decarboxylase deficiency 65
Functional Characterization of a Spectrum of Genetic Variants in a Family with Succinic Semialdehyde Dehydrogenase Deficiency 65
The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis 64
Exome sequencing data screening to identify undiagnosed Aromatic l-amino acid decarboxylase deficiency in neurodevelopmental disorders 62
An attenuated, adult case of AADC deficiency demonstrated by protein characterization 61
Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes 58
Succinic semialdehyde dehydrogenase deficiency: in vitro and in silico characterization of a novel pathogenic missense variant and analysis of the mutational spectrum of ALDH5A1 54
Case report: Childhood epilepsy and borderline intellectual functioning hiding an AADC deficiency disorder associated with compound heterozygous DDC gene pathogenic variants 53
A crucial active site network of titratable residues guides catalysis and NAD+ binding in human succinic semialdehyde dehydrogenase 51
Mild/moderate phenotypes in AADC deficiency: Focus on the aromatic amino acid decarboxylase protein 50
Consensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency 48
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder 46
Active site serine-193 modulates activity of human aromatic amino acid decarboxylase 46
Mitapivat metabolically reprograms human beta-thalassemic erythroblasts, increasing their responsiveness to oxidation 44
The presence and severity of epilepsy coincide with reduced GABA and cortical excitatory markers in SSADH deficiency 42
REVEAL-CP: Selective Screening of Pediatric Patients for Aromatic L-Amino Acid Decarboxylase Deficiency with a Guthrie Card and In Silico Structural Modeling of One Index Case 42
Navigating the rare neurotransmitter disease diagnosis: insights from patients and health care professionals 40
Phenotypic correlates of structural and functional protein impairments resultant from ALDH5A1 variants 40
Central Dysmyelination in SSADH-Deficient Humans and Mice 36
The integrated approach to inherited disorders in neurotransmitters from molecules to systems 34
Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions 32
α-Hydrazino Acids Inhibit Pyridoxal Phosphate-Dependent Decarboxylases via “Catalytically Correct” Ketoenamine Tautomers: A Special Motif for Chemical Biology and Drug Discovery? 31
Pharmacological Inhibition of Calpain-1 Prevents Red Cell Dehydration and Reduces Gardos Channel Activity in a Mouse Model of Sickle Cell Disease. Identification of Druggable Protease Target 30
Gene replacement therapies for inherited disorders of neurotransmission: Current progress in succinic semialdehyde dehydrogenase deficiency 30
PEROXIREDOXIN-2 (Prx2) MEMBRANE DISPLACEMENT IS A NEW ADDITIONAL FACTOR to the SEVERITY of beta-THALASSEMIC MOUSE RED CELL MEMBRANE DAMAGE 28
Green tea polyphenols: novel irreversible inhibitors of dopa decarboxylase 25
Neurotransmitters … it is all about communication! 23
The neuropsychological profile of SSADH deficiency, a neurotransmitter disorder of GABA metabolism 19
Totale 9.346
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Categoria #
all - tutte 34.861
article - articoli 32.598
book - libri 0
conference - conferenze 1.274
curatela - curatele 0
other - altro 374
patent - brevetti 0
selected - selezionate 0
volume - volumi 615
Totale 69.722
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021315 0 0 0 0 44 69 9 62 25 7 62 37
2021/2022749 47 241 126 30 19 16 5 24 25 22 45 149
2022/20231.052 84 99 110 196 80 253 20 49 112 9 21 19
2023/2024580 30 48 32 93 60 66 22 25 12 19 127 46
2024/20251.966 102 88 46 347 62 46 97 86 307 152 213 420
2025/20262.097 430 279 482 860 46 0 0 0 0 0 0 0
Totale 9.346