CATALOGO DEI PRODOTTI DELLA RICERCA

BERTOLDI, Mariarita
 Distribuzione geografica
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Continente #
NA - Nord America 2.177
EU - Europa 2.034
AS - Asia 787
SA - Sud America 8
OC - Oceania 4
AF - Africa 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.015
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Nazione #
US - Stati Uniti d'America 2.162
GB - Regno Unito 980
CN - Cina 713
FR - Francia 194
IT - Italia 187
SE - Svezia 162
FI - Finlandia 156
IE - Irlanda 148
DE - Germania 107
UA - Ucraina 55
VN - Vietnam 37
BE - Belgio 15
CA - Canada 13
RU - Federazione Russa 9
TR - Turchia 7
JP - Giappone 6
KR - Corea 6
CL - Cile 5
ES - Italia 4
NL - Olanda 4
RO - Romania 4
SG - Singapore 4
AU - Australia 3
CH - Svizzera 3
HK - Hong Kong 3
IL - Israele 3
BR - Brasile 2
IN - India 2
NG - Nigeria 2
SA - Arabia Saudita 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CR - Costa Rica 1
EU - Europa 1
GR - Grecia 1
HU - Ungheria 1
KG - Kirghizistan 1
MA - Marocco 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PL - Polonia 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 5.015
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Città #
Southend 924
Jacksonville 405
Chandler 313
Woodbridge 226
Ann Arbor 198
Houston 188
Dublin 148
Ashburn 116
Beijing 105
Jinan 102
Verona 96
Shenyang 73
Wilmington 73
Lawrence 69
Princeton 69
Nanjing 62
Helsinki 52
Hebei 44
New York 42
Changsha 35
Ningbo 31
Zhengzhou 30
Tianjin 27
Falls Church 21
Haikou 21
Hangzhou 19
Sindelfingen 19
Taiyuan 18
Nanchang 17
Milan 16
Redmond 16
Taizhou 16
Seattle 15
Brussels 14
Dong Ket 14
Guangzhou 14
Lancaster 14
Chicago 13
Jiaxing 13
Norwalk 13
Fuzhou 12
Lanzhou 12
Boardman 7
Fairfield 7
Renton 7
Rome 7
San Francisco 7
Elora 6
Padova 6
Redwood City 6
Riva 6
Seoul 6
Toronto 6
Berlin 5
Clearwater 5
Los Angeles 5
Rubano 5
Dearborn 4
Tokyo 4
Auburn Hills 3
Detroit 3
Gardone Val Trompia 3
Kemerovo 3
London 3
Pieve di Soligo 3
Shanghai 3
Singapore 3
Tezze Sul Brenta 3
Abano Terme 2
Amsterdam 2
Bayonne 2
Changle 2
Chions 2
Dongguan 2
Glasgow 2
Haifa 2
Hong Kong 2
Kiev 2
Las Vegas 2
Nürnberg 2
Perugia 2
Phoenix 2
Ponte di Piave 2
Sassari 2
Sydney 2
Timisoara 2
Washington 2
Xiangfen 2
Agrate Brianza 1
Asti 1
Auckland 1
Augusta 1
Bishkek 1
Bologna 1
Boston 1
Bratislava 1
Brescia 1
Budapest 1
Buffalo 1
Cambridge 1
Totale 3.903
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Nome #
Dimerization and Folding Processes of Treponema denticola Cystalysin: The Role of Pyridoxal 5'-Phosphate 132
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 131
Holo-and apocystalysin from Treponema denticola: two different conformations 126
The novel R347g pathogenic mutation Of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency 111
Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice 107
Dopa decarboxylase exhibits low pH half-transaminase and high pH oxidative deaminase activities toward serotonin (5-hydroxytryptamine) 106
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 103
Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band3 99
Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii 96
Structural properties of trimers and tetramers of ribonuclease A 95
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 94
Oxidative stress and b-thalasssemic erythroid cells behind the molecular defect 94
Oxidative stress modulates heme levels and induces peroxiredoxin-2 in β thalassemic erythropoiesis as novel cytoprotective response 93
Mutation of residues in the coenzyme binding pocket of Dopa decarboxylase: effects on catalytic properties 90
Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease 90
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 88
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice 88
Dopa decarboxylase 86
Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase 85
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase 83
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 83
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity 83
Insights into the mechanism of oxidative deamination catalyzed by Dopa decarboxylase 81
Phosphorylation of pyridoxal 5'-phosphate enzymes: an intriguing and neglected topic 81
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 80
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 80
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 77
Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease 77
New insights emerging from recent investigations on human group II pyridoxal 5'-phosphate Decarboxylases 77
The novel role of peroxiredoxin-2 in red cell membrane protein homeostasis and senescence. 75
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis 74
Pathogenic variants of human Aromatic L-Amino Acid Decarboxylase: evidences of misfolding in functionally active variants 73
Reaction specificity of native and nicked 3,4-dihydroxyphenylalanine decarboxylase 72
Dopa decarboxylase 71
Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis? 70
Reaction of Dopa decarboxylase with alfa-methylDopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active-site directed affinity label 69
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 69
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 68
New variants of AADC deficiency expand the knowledge of enzymatic phenotypes 68
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their alpha-methyl substrates 67
Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis 66
Cysteine 180 Is a Redox Sensor Modulating the Activity of Human Pyridoxal 5'-Phosphate Histidine Decarboxylase 66
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 65
Mutation of cysteine 111 in dopa decarboxylase leads to active site perturbation 65
Mechanism-based inactivation of dopa decarboxylase by serotonin 64
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 64
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 64
Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations 64
Peroxiredoxin-2 (Prx2) expression is increased in beta thalassemic mouse red cells but displaced from the membrane as marker of oxidative stress 63
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 62
Human peroxiredoxins 1 and 2 and their interacting protein partners; through structure toward functions of biological complexes 62
Mutation of tyrosine 332 to phenylalanine converts Dopa decarboxylase into a decarboxylation-dependent oxidative deaminase 61
Parkinson's Disease: recent updates in the identification of human dopa decarboxylase inhibitors 60
Aromatic amino acid decarboxylase deficiency: Molecular and metabolic basis and therapeutic outlook 60
The activity on double-stranded RNA of aggregates of Ribonuclease A higher than dimers increases as a function of the size of the aggregates 57
Multiple roles of the active site lysine of Dopa decarboxylase 55
Reaction and substrate specificity of pig kidney Dopa decarboxylase under aerobic and anaerobic conditions 54
Compound heterozygosis in AADC deficiency: A complex phenotype dissected through comparison among heterodimeric and homodimeric AADC proteins 54
Tyrosine phosphorylation modulates peroxiredoxin-2 activity in normal and diseased red cells 52
Mapping of human autoantibody epitopes on aromatic l-amino acid decarboxylase 51
Oxygen reactivity with pyridoxal 5'-phosphate enzymes: biochemical implications and functional relevance 50
Structural insights into the heme pocket and oligomeric state of non-symbiotic hemoglobins from Arabidopsis thaliana 45
Mammalian Dopa decarboxylase: structure, catalytic activity and inhibition 40
Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: Could such a scenario be helpful to counteract COVID-19? 37
Human DOPA decarboxylase: catalysis and involvement in pharmacologica treatments of Parkinson's disease and aromatic amino acid decarboxylase deficiency 36
Aromatic l-amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies 33
A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies 30
Succinic semialdehyde dehydrogenase deficiency: in vitro and in silico characterization of a novel pathogenic missense variant and analysis of the mutational spectrum of ALDH5A1 27
The novel P330L pathogenic variant of aromatic amino acid decarboxylase maps on the catalytic flexible loop underlying its crucial role 22
Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: implication in AADC deficiency 16
Compound heterozygosis in AADC deficiency and its complex phenotype in terms of AADC protein population 15
The presence and severity of epilepsy coincide with reduced GABA and cortical excitatory markers in SSADH deficiency 13
Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency 10
Exome sequencing data screening to identify undiagnosed Aromatic l-amino acid decarboxylase deficiency in neurodevelopmental disorders 8
An attenuated, adult case of AADC deficiency demonstrated by protein characterization 7
Active site serine-193 modulates activity of human aromatic amino acid decarboxylase 7
Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes 6
The integrated approach to inherited disorders in neurotransmitters from molecules to systems 4
Consensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency 3
Case report: Childhood epilepsy and borderline intellectual functioning hiding an AADC deficiency disorder associated with compound heterozygous DDC gene pathogenic variants 3
Gene replacement therapies for inherited disorders of neurotransmission: Current progress in succinic semialdehyde dehydrogenase deficiency 2
Navigating the rare neurotransmitter disease diagnosis: insights from patients and health care professionals 2
Phenotypic correlates of structural and functional protein impairments resultant from ALDH5A1 variants 2
Green tea polyphenols: novel irreversible inhibitors of dopa decarboxylase 2
Pharmacological Inhibition of Calpain-1 Prevents Red Cell Dehydration and Reduces Gardos Channel Activity in a Mouse Model of Sickle Cell Disease. Identification of Druggable Protease Target 1
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder 1
Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions 1
PEROXIREDOXIN-2 (Prx2) MEMBRANE DISPLACEMENT IS A NEW ADDITIONAL FACTOR to the SEVERITY of beta-THALASSEMIC MOUSE RED CELL MEMBRANE DAMAGE 1
Totale 5.125
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Categoria #
all - tutte 15.424
article - articoli 14.224
book - libri 0
conference - conferenze 666
curatela - curatele 0
other - altro 210
patent - brevetti 0
selected - selezionate 0
volume - volumi 324
Totale 30.848
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201946 0 0 0 0 0 0 0 0 0 0 15 31
2019/2020680 83 9 6 49 51 71 86 46 38 71 43 127
2020/2021625 101 109 51 49 44 69 9 62 25 7 62 37
2021/2022749 47 241 126 30 19 16 5 24 25 22 45 149
2022/20231.052 84 99 110 196 80 253 20 49 112 9 21 19
2023/2024422 30 48 32 93 60 66 22 25 12 19 15 0
Totale 5.125