CATALOGO DEI PRODOTTI DELLA RICERCA

BERTOLDI, Mariarita
 Distribuzione geografica
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Continente #
NA - Nord America 5.863
EU - Europa 4.508
AS - Asia 3.646
SA - Sud America 471
Continente sconosciuto - Info sul continente non disponibili 158
AF - Africa 96
OC - Oceania 8
Totale 14.750
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Nazione #
US - Stati Uniti d'America 5.650
RU - Federazione Russa 1.767
SG - Singapore 1.394
CN - Cina 1.139
GB - Regno Unito 1.065
IT - Italia 484
BR - Brasile 371
VN - Vietnam 343
HK - Hong Kong 319
FR - Francia 223
DE - Germania 213
FI - Finlandia 200
SE - Svezia 169
IE - Irlanda 153
KR - Corea 103
CA - Canada 101
BD - Bangladesh 78
UA - Ucraina 59
IN - India 47
ID - Indonesia 40
AR - Argentina 39
NL - Olanda 38
JP - Giappone 35
IQ - Iraq 24
TR - Turchia 23
MX - Messico 22
CR - Costa Rica 21
AT - Austria 20
ES - Italia 20
NG - Nigeria 20
BE - Belgio 19
LT - Lituania 19
PL - Polonia 18
TG - Togo 15
BJ - Benin 14
IL - Israele 13
SA - Arabia Saudita 13
CO - Colombia 12
EC - Ecuador 12
JO - Giordania 12
TT - Trinidad e Tobago 12
UZ - Uzbekistan 12
ZA - Sudafrica 12
GT - Guatemala 11
CL - Cile 10
PK - Pakistan 10
MA - Marocco 9
PR - Porto Rico 9
SV - El Salvador 9
NI - Nicaragua 7
UY - Uruguay 7
BG - Bulgaria 6
HN - Honduras 6
JM - Giamaica 6
PY - Paraguay 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
BO - Bolivia 5
EG - Egitto 5
MY - Malesia 5
PH - Filippine 5
TN - Tunisia 5
CH - Svizzera 4
CW - ???statistics.table.value.countryCode.CW??? 4
PE - Perù 4
SC - Seychelles 4
SK - Slovacchia (Repubblica Slovacca) 4
BH - Bahrain 3
DK - Danimarca 3
GR - Grecia 3
KE - Kenya 3
NP - Nepal 3
VE - Venezuela 3
AL - Albania 2
AZ - Azerbaigian 2
BS - Bahamas 2
EE - Estonia 2
ET - Etiopia 2
GE - Georgia 2
GP - Guadalupe 2
HU - Ungheria 2
KG - Kirghizistan 2
LB - Libano 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PS - Palestinian Territory 2
TH - Thailandia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BY - Bielorussia 1
BZ - Belize 1
CI - Costa d'Avorio 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EU - Europa 1
Totale 14.579
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Città #
Southend 924
Ashburn 800
Singapore 763
San Jose 662
Moscow 610
Dallas 421
Jacksonville 406
Hong Kong 316
Chandler 313
Verona 233
Woodbridge 226
Ann Arbor 198
Houston 198
Beijing 197
Council Bluffs 177
Dublin 151
The Dalles 131
Jinan 102
Ho Chi Minh City 97
Los Angeles 93
New York 74
Shenyang 74
Wilmington 73
Princeton 70
Hanoi 69
Lawrence 69
Santa Clara 67
Helsinki 62
Nanjing 62
Buffalo 54
Munich 45
Hebei 44
São Paulo 40
Columbus 39
Tianjin 37
Changsha 36
Milan 33
Tokyo 33
Las Vegas 32
Zhengzhou 32
Ningbo 31
Frankfurt am Main 29
London 29
Chicago 28
Jakarta 28
Orem 28
Montreal 27
Seattle 27
Redondo Beach 26
Hangzhou 23
Falls Church 21
Guangzhou 21
Haikou 21
Denver 20
Phoenix 20
Toronto 20
Brooklyn 19
Lappeenranta 19
Sindelfingen 19
Amsterdam 18
Rome 18
Taiyuan 18
Abuja 17
Atlanta 17
Nanchang 17
San Francisco 17
Brussels 16
Lancaster 16
Nuremberg 16
Redmond 16
San José 16
Taizhou 16
Chennai 15
Lomé 15
Turku 15
Warsaw 15
Cotonou 14
Dong Ket 14
Norwalk 14
Boardman 13
Fuzhou 13
Jiaxing 13
Lanzhou 13
Amman 12
Bologna 12
Da Nang 12
Hải Dương 12
Boston 11
McKinney 11
Rio de Janeiro 11
Seoul 11
Baghdad 10
North Bergen 10
Shanghai 10
Tashkent 10
Vienna 10
Vilnius 10
Washington 10
Cleveland 9
Haiphong 9
Totale 9.071
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Nome #
Dimerization and Folding Processes of Treponema denticola Cystalysin: The Role of Pyridoxal 5'-Phosphate 304
Holo-and apocystalysin from Treponema denticola: two different conformations 288
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 281
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 244
Pathogenic variants of human Aromatic L-Amino Acid Decarboxylase: evidences of misfolding in functionally active variants 242
Dopa decarboxylase exhibits low pH half-transaminase and high pH oxidative deaminase activities toward serotonin (5-hydroxytryptamine) 233
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis 231
The novel R347g pathogenic mutation Of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency 223
Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice 220
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 219
Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii 217
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 216
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 208
Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band3 206
Structural properties of trimers and tetramers of ribonuclease A 205
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity 196
Cysteine 180 Is a Redox Sensor Modulating the Activity of Human Pyridoxal 5'-Phosphate Histidine Decarboxylase 195
New variants of AADC deficiency expand the knowledge of enzymatic phenotypes 192
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase 188
Phosphorylation of pyridoxal 5'-phosphate enzymes: an intriguing and neglected topic 188
Oxidative stress and b-thalasssemic erythroid cells behind the molecular defect 188
Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase 187
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 187
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice 179
Oxidative stress modulates heme levels and induces peroxiredoxin-2 in β thalassemic erythropoiesis as novel cytoprotective response 178
Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease 177
Mutation of residues in the coenzyme binding pocket of Dopa decarboxylase: effects on catalytic properties 176
Aromatic amino acid decarboxylase deficiency: Molecular and metabolic basis and therapeutic outlook 174
New insights emerging from recent investigations on human group II pyridoxal 5'-phosphate Decarboxylases 168
Compound heterozygosis in AADC deficiency: A complex phenotype dissected through comparison among heterodimeric and homodimeric AADC proteins 163
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 161
Oxygen reactivity with pyridoxal 5'-phosphate enzymes: biochemical implications and functional relevance 157
Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis 155
Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease 155
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 155
A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies 154
The novel role of peroxiredoxin-2 in red cell membrane protein homeostasis and senescence. 153
Dopa decarboxylase 152
Mutation of cysteine 111 in dopa decarboxylase leads to active site perturbation 152
Tyrosine phosphorylation modulates peroxiredoxin-2 activity in normal and diseased red cells 150
Insights into the mechanism of oxidative deamination catalyzed by Dopa decarboxylase 148
Consensus Guideline for the Diagnosis and Treatment of Tyrosine Hydroxylase (TH) Deficiency 147
Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations 147
Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: Could such a scenario be helpful to counteract COVID-19? 145
Aromatic l-amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies 145
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 144
Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis? 142
Parkinson's Disease: recent updates in the identification of human dopa decarboxylase inhibitors 142
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 141
The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis 138
Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency 138
Compound heterozygosis in AADC deficiency and its complex phenotype in terms of AADC protein population 138
Mechanism-based inactivation of dopa decarboxylase by serotonin 138
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 137
Peroxiredoxin-2 (Prx2) expression is increased in beta thalassemic mouse red cells but displaced from the membrane as marker of oxidative stress 136
Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: implication in AADC deficiency 135
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 133
Reaction specificity of native and nicked 3,4-dihydroxyphenylalanine decarboxylase 132
Dopa decarboxylase 131
The novel P330L pathogenic variant of aromatic amino acid decarboxylase maps on the catalytic flexible loop underlying its crucial role 131
Reaction and substrate specificity of pig kidney Dopa decarboxylase under aerobic and anaerobic conditions 129
An attenuated, adult case of AADC deficiency demonstrated by protein characterization 127
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their alpha-methyl substrates 127
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 126
Multiple roles of the active site lysine of Dopa decarboxylase 126
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 126
The activity on double-stranded RNA of aggregates of Ribonuclease A higher than dimers increases as a function of the size of the aggregates 125
Mutation of tyrosine 332 to phenylalanine converts Dopa decarboxylase into a decarboxylation-dependent oxidative deaminase 123
Reaction of Dopa decarboxylase with alfa-methylDopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active-site directed affinity label 122
Human peroxiredoxins 1 and 2 and their interacting protein partners; through structure toward functions of biological complexes 122
Consensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency 121
A crucial active site network of titratable residues guides catalysis and NAD+ binding in human succinic semialdehyde dehydrogenase 120
Mapping of human autoantibody epitopes on aromatic l-amino acid decarboxylase 118
Case report: Childhood epilepsy and borderline intellectual functioning hiding an AADC deficiency disorder associated with compound heterozygous DDC gene pathogenic variants 118
Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes 117
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder 116
Exome sequencing data screening to identify undiagnosed Aromatic l-amino acid decarboxylase deficiency in neurodevelopmental disorders 116
Functional Characterization of a Spectrum of Genetic Variants in a Family with Succinic Semialdehyde Dehydrogenase Deficiency 116
Active site serine-193 modulates activity of human aromatic amino acid decarboxylase 113
Structural insights into the heme pocket and oligomeric state of non-symbiotic hemoglobins from Arabidopsis thaliana 113
Mild/moderate phenotypes in AADC deficiency: Focus on the aromatic amino acid decarboxylase protein 112
Mitapivat metabolically reprograms human beta-thalassemic erythroblasts, increasing their responsiveness to oxidation 112
Mammalian Dopa decarboxylase: structure, catalytic activity and inhibition 111
The presence and severity of epilepsy coincide with reduced GABA and cortical excitatory markers in SSADH deficiency 105
Human DOPA decarboxylase: catalysis and involvement in pharmacologica treatments of Parkinson's disease and aromatic amino acid decarboxylase deficiency 96
α-Hydrazino Acids Inhibit Pyridoxal Phosphate-Dependent Decarboxylases via “Catalytically Correct” Ketoenamine Tautomers: A Special Motif for Chemical Biology and Drug Discovery? 92
Central Dysmyelination in SSADH-Deficient Humans and Mice 91
Succinic semialdehyde dehydrogenase deficiency: in vitro and in silico characterization of a novel pathogenic missense variant and analysis of the mutational spectrum of ALDH5A1 90
REVEAL-CP: Selective Screening of Pediatric Patients for Aromatic L-Amino Acid Decarboxylase Deficiency with a Guthrie Card and In Silico Structural Modeling of One Index Case 87
Phenotypic correlates of structural and functional protein impairments resultant from ALDH5A1 variants 86
Navigating the rare neurotransmitter disease diagnosis: insights from patients and health care professionals 81
Green tea polyphenols: novel irreversible inhibitors of dopa decarboxylase 76
Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions 70
The neuropsychological profile of SSADH deficiency, a neurotransmitter disorder of GABA metabolism 68
The integrated approach to inherited disorders in neurotransmitters from molecules to systems 62
Gene replacement therapies for inherited disorders of neurotransmission: Current progress in succinic semialdehyde dehydrogenase deficiency 60
Pharmacological Inhibition of Calpain-1 Prevents Red Cell Dehydration and Reduces Gardos Channel Activity in a Mouse Model of Sickle Cell Disease. Identification of Druggable Protease Target 57
Neurotransmitters … it is all about communication! 54
PEROXIREDOXIN-2 (Prx2) MEMBRANE DISPLACEMENT IS A NEW ADDITIONAL FACTOR to the SEVERITY of beta-THALASSEMIC MOUSE RED CELL MEMBRANE DAMAGE 48
N-acetyl-l-leucine lowers α-synuclein levels and improves synaptic function in Parkinson's disease models 41
Totale 14.625
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Categoria #
all - tutte 51.341
article - articoli 48.046
book - libri 0
conference - conferenze 1.994
curatela - curatele 0
other - altro 481
patent - brevetti 0
selected - selezionate 0
volume - volumi 820
Totale 102.682
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022305 0 0 0 0 19 16 5 24 25 22 45 149
2022/20231.052 84 99 110 196 80 253 20 49 112 9 21 19
2023/2024580 30 48 32 93 60 66 22 25 12 19 127 46
2024/20251.966 102 88 46 347 62 46 97 86 307 152 213 420
2025/20266.030 430 279 482 860 1.512 388 599 333 488 382 137 140
2026/20271.471 95 200 230 837 109 0 0 0 0 0 0 0
Totale 14.750