CATALOGO DEI PRODOTTI DELLA RICERCA

BERTOLDI, Mariarita
 Distribuzione geografica
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Continente #
NA - Nord America 4.616
EU - Europa 4.378
AS - Asia 3.586
SA - Sud America 452
AF - Africa 92
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 2
Totale 13.134
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Nazione #
US - Stati Uniti d'America 4.532
RU - Federazione Russa 1.759
SG - Singapore 1.381
CN - Cina 1.124
GB - Regno Unito 1.046
IT - Italia 415
BR - Brasile 359
VN - Vietnam 341
HK - Hong Kong 314
FR - Francia 216
DE - Germania 207
FI - Finlandia 200
SE - Svezia 169
IE - Irlanda 151
KR - Corea 103
BD - Bangladesh 71
UA - Ucraina 59
CA - Canada 50
IN - India 46
AR - Argentina 38
ID - Indonesia 38
NL - Olanda 36
JP - Giappone 33
IQ - Iraq 24
TR - Turchia 22
AT - Austria 20
MX - Messico 20
NG - Nigeria 20
ES - Italia 19
BE - Belgio 18
PL - Polonia 16
TG - Togo 15
BJ - Benin 14
JO - Giordania 12
UZ - Uzbekistan 12
ZA - Sudafrica 12
EC - Ecuador 11
SA - Arabia Saudita 11
CL - Cile 10
LT - Lituania 10
MA - Marocco 9
PK - Pakistan 9
IL - Israele 8
CO - Colombia 7
UY - Uruguay 7
BG - Bulgaria 6
PY - Paraguay 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
BO - Bolivia 5
EG - Egitto 5
TN - Tunisia 5
CH - Svizzera 4
MY - Malesia 4
PE - Perù 4
PH - Filippine 4
RO - Romania 4
SK - Slovacchia (Repubblica Slovacca) 4
CR - Costa Rica 3
DK - Danimarca 3
GR - Grecia 3
JM - Giamaica 3
KE - Kenya 3
NP - Nepal 3
VE - Venezuela 3
AL - Albania 2
AZ - Azerbaigian 2
BH - Bahrain 2
ET - Etiopia 2
GE - Georgia 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
LB - Libano 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PS - Palestinian Territory 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EU - Europa 1
GF - Guiana Francese 1
GH - Ghana 1
GY - Guiana 1
HR - Croazia 1
IS - Islanda 1
KH - Cambogia 1
KZ - Kazakistan 1
MD - Moldavia 1
MU - Mauritius 1
NI - Nicaragua 1
OM - Oman 1
PG - Papua Nuova Guinea 1
QA - Qatar 1
Totale 13.124
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Città #
Southend 924
Singapore 758
Moscow 610
Ashburn 597
San Jose 561
Dallas 407
Jacksonville 405
Chandler 313
Hong Kong 312
Verona 232
Woodbridge 226
Ann Arbor 198
Houston 195
Beijing 187
Dublin 151
The Dalles 130
Council Bluffs 102
Jinan 102
Ho Chi Minh City 97
Los Angeles 81
Shenyang 74
Wilmington 73
Hanoi 69
Lawrence 69
Princeton 69
Helsinki 62
Nanjing 62
New York 62
Buffalo 51
Munich 45
Hebei 44
Columbus 39
Tianjin 37
Changsha 36
São Paulo 36
Santa Clara 32
Zhengzhou 32
Ningbo 31
Tokyo 31
London 28
Jakarta 27
Orem 26
Redondo Beach 26
Frankfurt am Main 24
Seattle 24
Hangzhou 23
Milan 23
Chicago 22
Falls Church 21
Guangzhou 21
Haikou 21
Lappeenranta 19
Montreal 19
Sindelfingen 19
Amsterdam 18
Taiyuan 18
Abuja 17
Nanchang 17
Brussels 16
Denver 16
Nuremberg 16
Redmond 16
Rome 16
Taizhou 16
Chennai 15
Lomé 15
Turku 15
Cotonou 14
Dong Ket 14
Lancaster 14
Warsaw 14
Fuzhou 13
Jiaxing 13
Lanzhou 13
Norwalk 13
San Francisco 13
Toronto 13
Amman 12
Brooklyn 12
Da Nang 12
Hải Dương 12
Rio de Janeiro 11
Seoul 11
Baghdad 10
Bologna 10
Boston 10
Phoenix 10
Tashkent 10
Vienna 10
Boardman 9
Haiphong 9
Shanghai 9
Dhaka 8
Kent 8
Mexico City 8
Brasília 7
Can Tho 7
Fairfield 7
Istanbul 7
Renton 7
Totale 8.446
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Nome #
Dimerization and Folding Processes of Treponema denticola Cystalysin: The Role of Pyridoxal 5'-Phosphate 283
Holo-and apocystalysin from Treponema denticola: two different conformations 270
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 253
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 227
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis 221
The novel R347g pathogenic mutation Of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency 212
Pathogenic variants of human Aromatic L-Amino Acid Decarboxylase: evidences of misfolding in functionally active variants 209
Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice 208
Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii 203
Dopa decarboxylase exhibits low pH half-transaminase and high pH oxidative deaminase activities toward serotonin (5-hydroxytryptamine) 201
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 199
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 196
Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band3 190
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity 189
Artificial Ribonuclease A oligomers degrade double-stranded RNA with efficiency that increases as a function of the size of the oligomer 186
Structural properties of trimers and tetramers of ribonuclease A 182
Cysteine 180 Is a Redox Sensor Modulating the Activity of Human Pyridoxal 5'-Phosphate Histidine Decarboxylase 182
New variants of AADC deficiency expand the knowledge of enzymatic phenotypes 181
Oxidative stress and b-thalasssemic erythroid cells behind the molecular defect 178
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 176
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase 174
Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase 172
Phosphorylation of pyridoxal 5'-phosphate enzymes: an intriguing and neglected topic 172
Oxidative stress modulates heme levels and induces peroxiredoxin-2 in β thalassemic erythropoiesis as novel cytoprotective response 169
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice 169
Deoxygenation affects tyrosine phosphoproteome of red cell membrane from patients with sickle cell disease 166
Mutation of residues in the coenzyme binding pocket of Dopa decarboxylase: effects on catalytic properties 162
Aromatic amino acid decarboxylase deficiency: Molecular and metabolic basis and therapeutic outlook 162
New insights emerging from recent investigations on human group II pyridoxal 5'-phosphate Decarboxylases 159
Compound heterozygosis in AADC deficiency: A complex phenotype dissected through comparison among heterodimeric and homodimeric AADC proteins 154
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 153
Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease 146
The novel role of peroxiredoxin-2 in red cell membrane protein homeostasis and senescence. 146
Dopa decarboxylase 145
Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis 145
Oxygen reactivity with pyridoxal 5'-phosphate enzymes: biochemical implications and functional relevance 144
A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies 143
Tyrosine phosphorylation modulates peroxiredoxin-2 activity in normal and diseased red cells 143
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 143
Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations 137
Mutation of cysteine 111 in dopa decarboxylase leads to active site perturbation 136
Insights into the mechanism of oxidative deamination catalyzed by Dopa decarboxylase 135
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 134
Aromatic l-amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies 132
Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: Could such a scenario be helpful to counteract COVID-19? 131
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 130
Structural versatility of bovine ribonuclease A: distinct conformers of trimeric and tetrameric aggregates of the enzyme 130
Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis? 129
Peroxiredoxin-2 (Prx2) expression is increased in beta thalassemic mouse red cells but displaced from the membrane as marker of oxidative stress 128
Compound heterozygosis in AADC deficiency and its complex phenotype in terms of AADC protein population 127
Mechanism-based inactivation of dopa decarboxylase by serotonin 127
Parkinson's Disease: recent updates in the identification of human dopa decarboxylase inhibitors 125
Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency 124
Dopa decarboxylase 123
Reaction specificity of native and nicked 3,4-dihydroxyphenylalanine decarboxylase 123
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 121
Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: implication in AADC deficiency 120
The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis 119
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 118
An attenuated, adult case of AADC deficiency demonstrated by protein characterization 117
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 116
Human peroxiredoxins 1 and 2 and their interacting protein partners; through structure toward functions of biological complexes 115
The novel P330L pathogenic variant of aromatic amino acid decarboxylase maps on the catalytic flexible loop underlying its crucial role 115
The activity on double-stranded RNA of aggregates of Ribonuclease A higher than dimers increases as a function of the size of the aggregates 114
Reaction of Dopa decarboxylase with alfa-methylDopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active-site directed affinity label 113
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their alpha-methyl substrates 113
Mutation of tyrosine 332 to phenylalanine converts Dopa decarboxylase into a decarboxylation-dependent oxidative deaminase 113
Multiple roles of the active site lysine of Dopa decarboxylase 112
Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder 107
Structural insights into the heme pocket and oligomeric state of non-symbiotic hemoglobins from Arabidopsis thaliana 107
Exome sequencing data screening to identify undiagnosed Aromatic l-amino acid decarboxylase deficiency in neurodevelopmental disorders 106
A crucial active site network of titratable residues guides catalysis and NAD+ binding in human succinic semialdehyde dehydrogenase 105
Reaction and substrate specificity of pig kidney Dopa decarboxylase under aerobic and anaerobic conditions 104
Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes 102
Active site serine-193 modulates activity of human aromatic amino acid decarboxylase 102
Mapping of human autoantibody epitopes on aromatic l-amino acid decarboxylase 102
Functional Characterization of a Spectrum of Genetic Variants in a Family with Succinic Semialdehyde Dehydrogenase Deficiency 101
Case report: Childhood epilepsy and borderline intellectual functioning hiding an AADC deficiency disorder associated with compound heterozygous DDC gene pathogenic variants 101
Mild/moderate phenotypes in AADC deficiency: Focus on the aromatic amino acid decarboxylase protein 100
Mammalian Dopa decarboxylase: structure, catalytic activity and inhibition 100
Consensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency 96
Consensus Guideline for the Diagnosis and Treatment of Tyrosine Hydroxylase (TH) Deficiency 93
Mitapivat metabolically reprograms human beta-thalassemic erythroblasts, increasing their responsiveness to oxidation 93
Human DOPA decarboxylase: catalysis and involvement in pharmacologica treatments of Parkinson's disease and aromatic amino acid decarboxylase deficiency 87
Succinic semialdehyde dehydrogenase deficiency: in vitro and in silico characterization of a novel pathogenic missense variant and analysis of the mutational spectrum of ALDH5A1 85
REVEAL-CP: Selective Screening of Pediatric Patients for Aromatic L-Amino Acid Decarboxylase Deficiency with a Guthrie Card and In Silico Structural Modeling of One Index Case 79
α-Hydrazino Acids Inhibit Pyridoxal Phosphate-Dependent Decarboxylases via “Catalytically Correct” Ketoenamine Tautomers: A Special Motif for Chemical Biology and Drug Discovery? 77
Central Dysmyelination in SSADH-Deficient Humans and Mice 76
Phenotypic correlates of structural and functional protein impairments resultant from ALDH5A1 variants 74
Navigating the rare neurotransmitter disease diagnosis: insights from patients and health care professionals 70
The presence and severity of epilepsy coincide with reduced GABA and cortical excitatory markers in SSADH deficiency 67
Green tea polyphenols: novel irreversible inhibitors of dopa decarboxylase 58
Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions 57
The neuropsychological profile of SSADH deficiency, a neurotransmitter disorder of GABA metabolism 56
The integrated approach to inherited disorders in neurotransmitters from molecules to systems 55
Gene replacement therapies for inherited disorders of neurotransmission: Current progress in succinic semialdehyde dehydrogenase deficiency 53
Pharmacological Inhibition of Calpain-1 Prevents Red Cell Dehydration and Reduces Gardos Channel Activity in a Mouse Model of Sickle Cell Disease. Identification of Druggable Protease Target 50
Neurotransmitters … it is all about communication! 42
PEROXIREDOXIN-2 (Prx2) MEMBRANE DISPLACEMENT IS A NEW ADDITIONAL FACTOR to the SEVERITY of beta-THALASSEMIC MOUSE RED CELL MEMBRANE DAMAGE 40
Histone deacetylases in Duchenne muscular dystrophy: a role in the mechanism of disease and a target for inhibition 19
Totale 13.254
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Categoria #
all - tutte 44.744
article - articoli 41.913
book - libri 0
conference - conferenze 1.660
curatela - curatele 0
other - altro 439
patent - brevetti 0
selected - selezionate 0
volume - volumi 732
Totale 89.488
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202137 0 0 0 0 0 0 0 0 0 0 0 37
2021/2022749 47 241 126 30 19 16 5 24 25 22 45 149
2022/20231.052 84 99 110 196 80 253 20 49 112 9 21 19
2023/2024580 30 48 32 93 60 66 22 25 12 19 127 46
2024/20251.966 102 88 46 347 62 46 97 86 307 152 213 420
2025/20266.030 430 279 482 860 1.512 388 599 333 488 382 137 140
Totale 13.279