PACCHIANA, Raffaella
 Distribuzione geografica
Continente #
NA - Nord America 2.025
EU - Europa 1.479
AS - Asia 757
SA - Sud America 18
AF - Africa 4
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 2
Totale 4.289
Nazione #
US - Stati Uniti d'America 2.007
GB - Regno Unito 490
CN - Cina 467
SG - Singapore 214
SE - Svezia 171
IT - Italia 154
RU - Federazione Russa 141
IE - Irlanda 131
FR - Francia 128
DE - Germania 88
FI - Finlandia 88
UA - Ucraina 32
BE - Belgio 26
TR - Turchia 18
CA - Canada 16
VN - Vietnam 15
BR - Brasile 13
JP - Giappone 10
ID - Indonesia 9
ES - Italia 8
KR - Corea 7
NL - Olanda 5
IN - India 4
AU - Australia 3
IR - Iran 3
LT - Lituania 3
RO - Romania 3
TG - Togo 3
AE - Emirati Arabi Uniti 2
EU - Europa 2
GR - Grecia 2
IQ - Iraq 2
NO - Norvegia 2
AM - Armenia 1
BO - Bolivia 1
BY - Bielorussia 1
CL - Cile 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
GL - Groenlandia 1
HK - Hong Kong 1
HU - Ungheria 1
IL - Israele 1
IM - Isola di Man 1
KG - Kirghizistan 1
MD - Moldavia 1
MY - Malesia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PA - Panama 1
PL - Polonia 1
PT - Portogallo 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 4.289
Città #
Southend 435
Chandler 399
Jacksonville 265
Woodbridge 210
Ann Arbor 183
Singapore 171
Ashburn 154
Dublin 129
Beijing 84
New York 81
Verona 80
Houston 70
Wilmington 66
Jinan 52
Lawrence 50
Princeton 50
Nanjing 36
Hebei 26
Brussels 25
Zhengzhou 21
Shenyang 20
Redmond 19
Tianjin 19
Helsinki 17
Haikou 13
Hangzhou 13
Washington 13
Dallas 12
Taizhou 12
Nanchang 10
Boardman 9
Jakarta 9
Ningbo 9
San Francisco 9
Sindelfingen 9
Jiaxing 8
Milan 8
Tokyo 8
Toronto 8
Dong Ket 7
Lanzhou 7
Redwood City 7
Seoul 7
Taiyuan 7
Changsha 6
Kent 6
Padova 6
Santa Clara 6
Caserta 5
Fuzhou 5
Guangzhou 5
Los Angeles 5
Falls Church 4
Lancaster 4
London 4
Madrid 4
Norwalk 4
Seattle 4
Trieste 4
Boydton 3
Fairfield 3
Kemerovo 3
Leawood 3
Lomé 3
Montréal 3
Munich 3
Riva 3
Shanghai 3
Treviso 3
Ardabil 2
Augusta 2
Baghdad 2
Carate Brianza 2
Clearwater 2
Düsseldorf 2
Esslingen am Neckar 2
Florence 2
Frankfurt am Main 2
Grassobbio 2
Groningen 2
Hefei 2
Legnago 2
Monmouth Junction 2
Mumbai 2
Nanyang 2
Newark 2
Novokuznetsk 2
Nürnberg 2
Pordenone 2
Ribeirão Preto 2
Rome 2
Tappahannock 2
Vancouver 2
Xiangfen 2
Almere Stad 1
Amsterdam 1
Athens 1
Atlanta 1
Auburn Hills 1
Auckland 1
Totale 3.005
Nome #
Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action. 121
BCL10 and PKC-zeta interactions in apoptosis of human cervical carcinoma cells triggered by etoposide 119
Amyloid-beta peptide induces HIF transcription factor and VEGF expression in cultured normal adult human astrocytes. 111
How β-amyloid proteins and pro-inflammatory cytokines might collaborate to produce the “Alzheimer brain”. 110
Abeta42 induction by its proxy, Abeta25-35, in cerebral normal human astrocytes requires calcium-sensing receptor (CaSR) signaling and nuclear translocation of HIF-1alpha/HIF-1beta complexes 110
CaSR INHIBITOR NPS2143 PREVENTS AMYLOID-β42 ACCUMULATION AND SECRETION IN NORMAL ADULT HUMAN ASTROCYTES AND POSTNATAL HUMAN NEURONS 108
Proteomic investigation into nonsyndromic aneurysm of the human ascenging aorta 107
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization 102
Involvement of protein kinase C-zeta at the nuclear membrane level of VP-16-treated human cervical carcinoma C4-I cells 101
The Amyloid-β42 Proxy, Amyloid-β25-35, induces normal human cerebral astrocytes to produce Amyloid-β42. 101
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease 100
JUNQUEIRA ISTOLOGIA TESTO ATLANTE 99
The calcium-sensing receptor: a novel Alzheimer’s disease crucial target? 99
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 98
Genomic and proteomic investigation into non-syndromic aneurysms of the human ascending aorta. 96
Analisi di espressione genica in aneurismi non sindromici dell’aorta ascendente 95
Proinflammatory cytokines and Amyloid β-(25-35) respectively stimulate VEGF-A production and secretion by cultured phenotypically normal adult human cerebral astrocytes 94
Soluble amyloid beta-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes 93
Proteomic investigations into non-syndromic aneurysms of the ascending aorta. 91
Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study 90
Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action. 89
Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action. 89
The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition 89
Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis 88
Nuclear lamin B1 is selectively destroyed by phoexcited calphostin C in neoplastic human and rat cells. 83
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy 83
UCP2 inhibition induces ROS/Akt/mTOR axis: role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 82
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells 82
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease. 82
Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia 80
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells 79
The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes 78
Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review) 77
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis 76
Regulation of autophagy by nuclear GAPDH and its aggregates in cancer and neurodegenerative disorders 76
Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells - A novel mechanism of action of a photodynamic tumor therapy agent 75
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study 74
Oncometabolites in cancer aggressiveness and tumour repopulation 73
Soluble amyloid β-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes. 72
Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease? 72
Molecular interplay between mutant p53 proteins and autophagy in cancer cells 72
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease 71
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine 70
Proteomic analysis of GTP cyclohydrolase I in multi-protein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions. 68
Autocrine mechanisms of cancer chemoresistance 68
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells 59
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC 56
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 50
Redox sensitive cysteine residues as crucial regulators of wild-type and mutant p53 isoforms 48
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 47
Regulation of succinate dehydrogenase and role of succinate in cancer 45
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 27
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism 26
Totale 4.351
Categoria #
all - tutte 15.513
article - articoli 10.589
book - libri 0
conference - conferenze 4.392
curatela - curatele 256
other - altro 276
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.026


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020281 0 0 0 0 0 55 49 27 8 54 22 66
2020/2021431 41 83 16 48 44 46 16 24 18 6 66 23
2021/2022429 51 114 3 16 26 8 7 31 17 12 34 110
2022/20231.049 67 138 82 198 84 242 9 68 119 5 26 11
2023/2024493 31 23 52 32 85 132 11 28 2 14 58 25
2024/2025504 56 72 40 236 66 34 0 0 0 0 0 0
Totale 4.351