PACCHIANA, Raffaella
 Distribuzione geografica
Continente #
NA - Nord America 2.655
EU - Europa 2.068
AS - Asia 1.438
SA - Sud America 186
AF - Africa 19
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.373
Nazione #
US - Stati Uniti d'America 2.609
CN - Cina 559
SG - Singapore 559
RU - Federazione Russa 528
GB - Regno Unito 512
IT - Italia 194
SE - Svezia 177
BR - Brasile 169
DE - Germania 151
FR - Francia 149
HK - Hong Kong 148
IE - Irlanda 131
FI - Finlandia 106
KR - Corea 32
UA - Ucraina 32
CA - Canada 28
BE - Belgio 26
VN - Vietnam 25
TR - Turchia 24
JP - Giappone 20
IN - India 16
MX - Messico 13
ES - Italia 12
ID - Indonesia 12
BD - Bangladesh 11
NL - Olanda 11
ZA - Sudafrica 10
PL - Polonia 9
AT - Austria 7
LT - Lituania 6
AE - Emirati Arabi Uniti 5
IQ - Iraq 5
AU - Australia 4
RO - Romania 4
UZ - Uzbekistan 4
AR - Argentina 3
CO - Colombia 3
IR - Iran 3
NO - Norvegia 3
TG - Togo 3
VE - Venezuela 3
BO - Bolivia 2
DZ - Algeria 2
EU - Europa 2
GR - Grecia 2
IL - Israele 2
MD - Moldavia 2
MY - Malesia 2
NP - Nepal 2
PH - Filippine 2
PY - Paraguay 2
AM - Armenia 1
AZ - Azerbaigian 1
BY - Bielorussia 1
CL - Cile 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
GL - Groenlandia 1
HU - Ungheria 1
IM - Isola di Man 1
JM - Giamaica 1
JO - Giordania 1
KG - Kirghizistan 1
KH - Cambogia 1
MA - Marocco 1
MG - Madagascar 1
MK - Macedonia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SA - Arabia Saudita 1
SN - Senegal 1
TH - Thailandia 1
TN - Tunisia 1
UY - Uruguay 1
Totale 6.373
Città #
Southend 435
Chandler 399
Dallas 271
Jacksonville 265
Singapore 242
Woodbridge 210
Ashburn 209
Ann Arbor 183
Hong Kong 147
Dublin 129
Moscow 129
Beijing 105
New York 93
Verona 93
Houston 73
Wilmington 66
Jinan 52
Lawrence 50
Princeton 50
Los Angeles 49
Munich 46
Nanjing 37
Hebei 26
Brussels 25
Tianjin 23
The Dalles 22
Zhengzhou 22
Buffalo 21
Shenyang 20
Redmond 19
Columbus 18
Tokyo 18
Helsinki 17
Hangzhou 16
Redondo Beach 16
Turku 16
Milan 15
San Francisco 14
Santa Clara 14
Haikou 13
São Paulo 13
Washington 13
Taizhou 12
Toronto 12
Jakarta 11
Boardman 10
Brooklyn 10
Nanchang 10
Ningbo 9
Sindelfingen 9
Frankfurt am Main 8
Jiaxing 8
London 8
Taiyuan 8
Chennai 7
Dong Ket 7
Guangzhou 7
Johannesburg 7
Lanzhou 7
Redwood City 7
Seattle 7
Seoul 7
Stockholm 7
Atlanta 6
Boston 6
Changsha 6
Fuzhou 6
Kent 6
Montreal 6
Nuremberg 6
Padova 6
Querétaro 6
Rio de Janeiro 6
Ankara 5
Caserta 5
Council Bluffs 5
Madrid 5
Manchester 5
Phoenix 5
Poplar 5
Roubaix 5
Warsaw 5
Amsterdam 4
Augusta 4
Campinas 4
Chicago 4
Falkenstein 4
Falls Church 4
Hefei 4
Lancaster 4
Norwalk 4
Orem 4
Porto Alegre 4
Rome 4
Secaucus 4
Shanghai 4
Tashkent 4
Trieste 4
Bexley 3
Boydton 3
Totale 4.047
Nome #
Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action. 183
BCL10 and PKC-zeta interactions in apoptosis of human cervical carcinoma cells triggered by etoposide 161
Amyloid-beta peptide induces HIF transcription factor and VEGF expression in cultured normal adult human astrocytes. 159
Abeta42 induction by its proxy, Abeta25-35, in cerebral normal human astrocytes requires calcium-sensing receptor (CaSR) signaling and nuclear translocation of HIF-1alpha/HIF-1beta complexes 156
CaSR INHIBITOR NPS2143 PREVENTS AMYLOID-β42 ACCUMULATION AND SECRETION IN NORMAL ADULT HUMAN ASTROCYTES AND POSTNATAL HUMAN NEURONS 153
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization 146
Proteomic investigation into nonsyndromic aneurysm of the human ascenging aorta 145
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 144
Analisi di espressione genica in aneurismi non sindromici dell’aorta ascendente 143
Genomic and proteomic investigation into non-syndromic aneurysms of the human ascending aorta. 141
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease 141
The calcium-sensing receptor: a novel Alzheimer’s disease crucial target? 139
Involvement of protein kinase C-zeta at the nuclear membrane level of VP-16-treated human cervical carcinoma C4-I cells 137
The Amyloid-β42 Proxy, Amyloid-β25-35, induces normal human cerebral astrocytes to produce Amyloid-β42. 134
Proinflammatory cytokines and Amyloid β-(25-35) respectively stimulate VEGF-A production and secretion by cultured phenotypically normal adult human cerebral astrocytes 130
JUNQUEIRA ISTOLOGIA TESTO ATLANTE 128
How β-amyloid proteins and pro-inflammatory cytokines might collaborate to produce the “Alzheimer brain”. 126
Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia 126
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease. 126
Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action. 123
Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis 123
Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study 123
Regulation of autophagy by nuclear GAPDH and its aggregates in cancer and neurodegenerative disorders 123
Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action. 122
The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition 122
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells 121
Proteomic investigations into non-syndromic aneurysms of the ascending aorta. 120
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease 118
UCP2 inhibition induces ROS/Akt/mTOR axis: role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 118
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy 115
Oncometabolites in cancer aggressiveness and tumour repopulation 115
Soluble amyloid beta-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes 113
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells 113
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis 112
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine 112
Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review) 108
Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells 107
Nuclear lamin B1 is selectively destroyed by phoexcited calphostin C in neoplastic human and rat cells. 107
Autocrine mechanisms of cancer chemoresistance 107
The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes 106
Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease? 105
Soluble amyloid β-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes. 103
Molecular interplay between mutant p53 proteins and autophagy in cancer cells 103
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells 97
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 96
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study 95
Redox sensitive cysteine residues as crucial regulators of wild-type and mutant p53 isoforms 92
Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells - A novel mechanism of action of a photodynamic tumor therapy agent 91
Proteomic analysis of GTP cyclohydrolase I in multi-protein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions. 91
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC 91
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 86
Regulation of succinate dehydrogenase and role of succinate in cancer 85
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 82
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism 73
Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenocarcinoma cells 6
Totale 6.442
Categoria #
all - tutte 23.195
article - articoli 16.211
book - libri 0
conference - conferenze 6.218
curatela - curatele 352
other - altro 414
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.390


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021243 0 0 0 0 44 46 16 24 18 6 66 23
2021/2022429 51 114 3 16 26 8 7 31 17 12 34 110
2022/20231.049 67 138 82 198 84 242 9 68 119 5 26 11
2023/2024493 31 23 52 32 85 132 11 28 2 14 58 25
2024/20251.182 56 72 40 236 66 42 56 40 199 69 96 210
2025/20261.413 261 172 294 609 77 0 0 0 0 0 0 0
Totale 6.442