PACCHIANA, Raffaella
 Distribuzione geografica
Continente #
NA - Nord America 3.609
EU - Europa 3.046
AS - Asia 2.065
SA - Sud America 283
Continente sconosciuto - Info sul continente non disponibili 76
AF - Africa 45
OC - Oceania 6
Totale 9.130
Nazione #
US - Stati Uniti d'America 3.512
RU - Federazione Russa 1.291
SG - Singapore 789
CN - Cina 642
GB - Regno Unito 538
IT - Italia 315
BR - Brasile 215
VN - Vietnam 184
SE - Svezia 180
HK - Hong Kong 162
DE - Germania 159
FR - Francia 159
IE - Irlanda 133
FI - Finlandia 113
KR - Corea 58
CA - Canada 53
BD - Bangladesh 50
IN - India 34
UA - Ucraina 34
TR - Turchia 32
BE - Belgio 26
JP - Giappone 26
MX - Messico 26
AR - Argentina 22
ES - Italia 22
NL - Olanda 18
EC - Ecuador 17
ID - Indonesia 17
PL - Polonia 14
IQ - Iraq 13
ZA - Sudafrica 13
AT - Austria 9
NG - Nigeria 9
VE - Venezuela 9
CO - Colombia 8
IL - Israele 8
LT - Lituania 6
UZ - Uzbekistan 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
CL - Cile 5
MY - Malesia 5
PH - Filippine 5
DO - Repubblica Dominicana 4
GR - Grecia 4
MA - Marocco 4
NP - Nepal 4
PT - Portogallo 4
RO - Romania 4
SA - Arabia Saudita 4
AZ - Azerbaigian 3
DZ - Algeria 3
IR - Iran 3
NO - Norvegia 3
PY - Paraguay 3
TG - Togo 3
BH - Bahrain 2
BJ - Benin 2
BO - Bolivia 2
CR - Costa Rica 2
DK - Danimarca 2
EG - Egitto 2
EU - Europa 2
GA - Gabon 2
HN - Honduras 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
MD - Moldavia 2
PA - Panama 2
PK - Pakistan 2
SI - Slovenia 2
SN - Senegal 2
TH - Thailandia 2
TN - Tunisia 2
AL - Albania 1
AM - Armenia 1
BB - Barbados 1
BY - Bielorussia 1
CH - Svizzera 1
GL - Groenlandia 1
HR - Croazia 1
HU - Ungheria 1
IM - Isola di Man 1
KG - Kirghizistan 1
KH - Cambogia 1
KZ - Kazakistan 1
MG - Madagascar 1
MK - Macedonia 1
MT - Malta 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
OM - Oman 1
PE - Perù 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
SV - El Salvador 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 9.056
Città #
Moscow 467
Southend 435
Singapore 407
Chandler 399
Ashburn 396
San Jose 287
Dallas 279
Jacksonville 266
Woodbridge 210
Ann Arbor 183
Hong Kong 160
Verona 155
Council Bluffs 131
Dublin 130
Beijing 120
New York 114
The Dalles 84
Houston 76
Wilmington 67
Los Angeles 61
Ho Chi Minh City 57
Jinan 54
Lawrence 50
Princeton 50
Munich 46
Hanoi 42
Nanjing 37
Santa Clara 28
Hebei 26
Tianjin 26
Brussels 25
Buffalo 24
Tokyo 24
Orem 23
Zhengzhou 23
Milan 22
São Paulo 22
Helsinki 21
Shenyang 20
Columbus 19
Redmond 19
Hangzhou 18
Redondo Beach 16
Toronto 16
Turku 16
Brooklyn 15
Frankfurt am Main 15
San Francisco 15
London 14
Montreal 14
Haikou 13
Washington 13
Jakarta 12
Taizhou 12
Atlanta 11
Chennai 11
Rome 11
Boardman 10
Nanchang 10
Querétaro 10
Stockholm 10
Abuja 9
Chicago 9
Haiphong 9
Jiaxing 9
Johannesburg 9
Madrid 9
Mexico City 9
Ningbo 9
Phoenix 9
Poplar 9
Sindelfingen 9
Warsaw 9
Amsterdam 8
Boston 8
Rio de Janeiro 8
Seattle 8
Taiyuan 8
Ankara 7
Baghdad 7
Dong Ket 7
Fuzhou 7
Guangzhou 7
Lanzhou 7
Nuremberg 7
Quito 7
Redwood City 7
Seoul 7
Changsha 6
Da Nang 6
Denver 6
Kent 6
Manchester 6
Padova 6
Shanghai 6
Caserta 5
Lappeenranta 5
Mumbai 5
Naples 5
Padua 5
Totale 5.632
Nome #
Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action. 240
BCL10 and PKC-zeta interactions in apoptosis of human cervical carcinoma cells triggered by etoposide 216
Abeta42 induction by its proxy, Abeta25-35, in cerebral normal human astrocytes requires calcium-sensing receptor (CaSR) signaling and nuclear translocation of HIF-1alpha/HIF-1beta complexes 216
Amyloid-beta peptide induces HIF transcription factor and VEGF expression in cultured normal adult human astrocytes. 212
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 208
Analisi di espressione genica in aneurismi non sindromici dell’aorta ascendente 206
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization 205
CaSR INHIBITOR NPS2143 PREVENTS AMYLOID-β42 ACCUMULATION AND SECRETION IN NORMAL ADULT HUMAN ASTROCYTES AND POSTNATAL HUMAN NEURONS 201
Genomic and proteomic investigation into non-syndromic aneurysms of the human ascending aorta. 197
Proteomic investigation into nonsyndromic aneurysm of the human ascenging aorta 195
The calcium-sensing receptor: a novel Alzheimer’s disease crucial target? 189
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells 189
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease 181
Involvement of protein kinase C-zeta at the nuclear membrane level of VP-16-treated human cervical carcinoma C4-I cells 178
Regulation of autophagy by nuclear GAPDH and its aggregates in cancer and neurodegenerative disorders 176
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease. 176
Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action. 174
The Amyloid-β42 Proxy, Amyloid-β25-35, induces normal human cerebral astrocytes to produce Amyloid-β42. 174
Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study 173
Proinflammatory cytokines and Amyloid β-(25-35) respectively stimulate VEGF-A production and secretion by cultured phenotypically normal adult human cerebral astrocytes 172
Oncometabolites in cancer aggressiveness and tumour repopulation 171
Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia 168
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease 168
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 167
Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action. 166
UCP2 inhibition induces ROS/Akt/mTOR axis: role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 165
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells 165
Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease? 164
Proteomic investigations into non-syndromic aneurysms of the ascending aorta. 163
How β-amyloid proteins and pro-inflammatory cytokines might collaborate to produce the “Alzheimer brain”. 163
JUNQUEIRA ISTOLOGIA TESTO ATLANTE 163
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells 162
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine 161
Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells 160
Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis 160
The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition 159
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy 157
Autocrine mechanisms of cancer chemoresistance 157
Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review) 156
Soluble amyloid beta-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes 151
The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes 149
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis 146
Molecular interplay between mutant p53 proteins and autophagy in cancer cells 145
Nuclear lamin B1 is selectively destroyed by phoexcited calphostin C in neoplastic human and rat cells. 143
Soluble amyloid β-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes. 139
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC 136
Regulation of succinate dehydrogenase and role of succinate in cancer 133
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 130
Proteomic analysis of GTP cyclohydrolase I in multi-protein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions. 128
Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells - A novel mechanism of action of a photodynamic tumor therapy agent 127
Redox sensitive cysteine residues as crucial regulators of wild-type and mutant p53 isoforms 125
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study 122
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 118
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism 111
Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenocarcinoma cells 95
Protein delivery to the eye: assessing therapeutic potential across inner and outer retina 29
Onconase Induces Apoptosis in Dabrafenib-Resistant Melanoma Cell Lines Through Dysregulation of ROS Homeostasis, Antioxidant Protein Expression, and Mitochondrial Dynamics 21
First-in-Class Covalent Inhibitors of PFKFB3: Discovery and Characterization in PDAC Models 9
Totale 9.130
Categoria #
all - tutte 31.053
article - articoli 22.050
book - libri 0
conference - conferenze 7.997
curatela - curatele 466
other - altro 540
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.106


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022264 0 0 3 16 26 8 7 31 17 12 34 110
2022/20231.049 67 138 82 198 84 242 9 68 119 5 26 11
2023/2024493 31 23 52 32 85 132 11 28 2 14 58 25
2024/20251.182 56 72 40 236 66 42 56 40 199 69 96 210
2025/20263.899 261 172 294 609 1.173 224 308 171 322 208 51 106
2026/2027202 57 99 46 0 0 0 0 0 0 0 0 0
Totale 9.130