PACCHIANA, Raffaella
 Distribuzione geografica
Continente #
EU - Europa 2.858
NA - Nord America 2.817
AS - Asia 1.727
SA - Sud America 237
AF - Africa 29
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 7.675
Nazione #
US - Stati Uniti d'America 2.748
RU - Federazione Russa 1.289
SG - Singapore 699
CN - Cina 598
GB - Regno Unito 518
IT - Italia 196
BR - Brasile 191
SE - Svezia 179
DE - Germania 158
HK - Hong Kong 150
FR - Francia 149
IE - Irlanda 131
FI - Finlandia 108
VN - Vietnam 102
CA - Canada 37
KR - Corea 37
UA - Ucraina 33
BE - Belgio 26
MX - Messico 25
TR - Turchia 25
JP - Giappone 23
IN - India 20
AR - Argentina 17
ES - Italia 16
BD - Bangladesh 15
ID - Indonesia 15
ZA - Sudafrica 13
NL - Olanda 12
PL - Polonia 11
AT - Austria 9
CO - Colombia 7
EC - Ecuador 7
VE - Venezuela 7
IL - Israele 6
LT - Lituania 6
AE - Emirati Arabi Uniti 5
IQ - Iraq 5
UZ - Uzbekistan 5
AU - Australia 4
RO - Romania 4
DO - Repubblica Dominicana 3
DZ - Algeria 3
IR - Iran 3
NO - Norvegia 3
NP - Nepal 3
PY - Paraguay 3
TG - Togo 3
AZ - Azerbaigian 2
BJ - Benin 2
BO - Bolivia 2
EU - Europa 2
GA - Gabon 2
GR - Grecia 2
JO - Giordania 2
MD - Moldavia 2
MY - Malesia 2
PH - Filippine 2
SN - Senegal 2
TH - Thailandia 2
AM - Armenia 1
BH - Bahrain 1
BY - Bielorussia 1
CL - Cile 1
DK - Danimarca 1
EG - Egitto 1
GL - Groenlandia 1
HU - Ungheria 1
IM - Isola di Man 1
JM - Giamaica 1
KG - Kirghizistan 1
KH - Cambogia 1
MA - Marocco 1
MG - Madagascar 1
MK - Macedonia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
QA - Qatar 1
SA - Arabia Saudita 1
TN - Tunisia 1
UY - Uruguay 1
Totale 7.675
Città #
Moscow 466
Southend 435
Chandler 399
Singapore 343
Dallas 271
Jacksonville 265
Ashburn 261
Woodbridge 210
Ann Arbor 183
Hong Kong 149
Dublin 129
Beijing 108
New York 98
Verona 93
Houston 74
Wilmington 66
Jinan 54
Los Angeles 52
Lawrence 50
Princeton 50
The Dalles 48
Munich 46
Nanjing 37
Ho Chi Minh City 29
Hebei 26
Tianjin 26
Brussels 25
Buffalo 23
Zhengzhou 23
Hanoi 21
Tokyo 21
Shenyang 20
Redmond 19
Columbus 18
Helsinki 18
Hangzhou 17
São Paulo 17
Redondo Beach 16
Santa Clara 16
Turku 16
Milan 15
Frankfurt am Main 14
San Francisco 14
Brooklyn 13
Haikou 13
Toronto 13
Washington 13
Taizhou 12
Jakarta 11
Montreal 11
Orem 11
Boardman 10
Nanchang 10
Querétaro 10
Jiaxing 9
Johannesburg 9
Ningbo 9
Poplar 9
Sindelfingen 9
Stockholm 9
Atlanta 8
Chennai 8
London 8
Mexico City 8
Taiyuan 8
Boston 7
Dong Ket 7
Fuzhou 7
Guangzhou 7
Lanzhou 7
Nuremberg 7
Phoenix 7
Redwood City 7
Rio de Janeiro 7
Seattle 7
Seoul 7
Warsaw 7
Ankara 6
Changsha 6
Kent 6
Padova 6
San Jose 6
Caserta 5
Chicago 5
Council Bluffs 5
Denver 5
Madrid 5
Manchester 5
Roubaix 5
Shanghai 5
Tashkent 5
Amsterdam 4
Augusta 4
Campinas 4
Falkenstein 4
Falls Church 4
Haiphong 4
Hefei 4
Lancaster 4
Mumbai 4
Totale 4.697
Nome #
Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action. 211
Amyloid-beta peptide induces HIF transcription factor and VEGF expression in cultured normal adult human astrocytes. 190
BCL10 and PKC-zeta interactions in apoptosis of human cervical carcinoma cells triggered by etoposide 188
Abeta42 induction by its proxy, Abeta25-35, in cerebral normal human astrocytes requires calcium-sensing receptor (CaSR) signaling and nuclear translocation of HIF-1alpha/HIF-1beta complexes 183
CaSR INHIBITOR NPS2143 PREVENTS AMYLOID-β42 ACCUMULATION AND SECRETION IN NORMAL ADULT HUMAN ASTROCYTES AND POSTNATAL HUMAN NEURONS 177
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization 177
Genomic and proteomic investigation into non-syndromic aneurysms of the human ascending aorta. 175
Analisi di espressione genica in aneurismi non sindromici dell’aorta ascendente 174
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 173
Proteomic investigation into nonsyndromic aneurysm of the human ascenging aorta 171
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease 167
The calcium-sensing receptor: a novel Alzheimer’s disease crucial target? 162
Involvement of protein kinase C-zeta at the nuclear membrane level of VP-16-treated human cervical carcinoma C4-I cells 160
Proinflammatory cytokines and Amyloid β-(25-35) respectively stimulate VEGF-A production and secretion by cultured phenotypically normal adult human cerebral astrocytes 157
Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action. 155
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease. 154
Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia 152
Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action. 150
The Amyloid-β42 Proxy, Amyloid-β25-35, induces normal human cerebral astrocytes to produce Amyloid-β42. 150
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease 150
Regulation of autophagy by nuclear GAPDH and its aggregates in cancer and neurodegenerative disorders 150
Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis 148
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells 146
Oncometabolites in cancer aggressiveness and tumour repopulation 146
Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study 145
Proteomic investigations into non-syndromic aneurysms of the ascending aorta. 144
The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition 143
How β-amyloid proteins and pro-inflammatory cytokines might collaborate to produce the “Alzheimer brain”. 142
UCP2 inhibition induces ROS/Akt/mTOR axis: role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 142
JUNQUEIRA ISTOLOGIA TESTO ATLANTE 140
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy 137
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine 137
Autocrine mechanisms of cancer chemoresistance 136
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis 135
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells 135
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 132
Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review) 131
Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease? 129
Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells 128
Soluble amyloid beta-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes 128
The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes 123
Molecular interplay between mutant p53 proteins and autophagy in cancer cells 123
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells 122
Nuclear lamin B1 is selectively destroyed by phoexcited calphostin C in neoplastic human and rat cells. 121
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC 117
Redox sensitive cysteine residues as crucial regulators of wild-type and mutant p53 isoforms 115
Soluble amyloid β-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes. 114
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 110
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 109
Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells - A novel mechanism of action of a photodynamic tumor therapy agent 105
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study 104
Proteomic analysis of GTP cyclohydrolase I in multi-protein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions. 102
Regulation of succinate dehydrogenase and role of succinate in cancer 94
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism 93
Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenocarcinoma cells 42
Totale 7.744
Categoria #
all - tutte 25.268
article - articoli 17.669
book - libri 0
conference - conferenze 6.767
curatela - curatele 378
other - altro 454
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.536


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021199 0 0 0 0 0 46 16 24 18 6 66 23
2021/2022429 51 114 3 16 26 8 7 31 17 12 34 110
2022/20231.049 67 138 82 198 84 242 9 68 119 5 26 11
2023/2024493 31 23 52 32 85 132 11 28 2 14 58 25
2024/20251.182 56 72 40 236 66 42 56 40 199 69 96 210
2025/20262.715 261 172 294 609 1.173 206 0 0 0 0 0 0
Totale 7.744