PACCHIANA, Raffaella
 Distribuzione geografica
Continente #
NA - Nord America 2.390
EU - Europa 1.640
AS - Asia 1.254
SA - Sud America 169
AF - Africa 14
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.474
Nazione #
US - Stati Uniti d'America 2.360
GB - Regno Unito 499
SG - Singapore 498
CN - Cina 476
IT - Italia 188
SE - Svezia 171
BR - Brasile 154
FR - Francia 148
DE - Germania 146
HK - Hong Kong 143
RU - Federazione Russa 143
IE - Irlanda 131
FI - Finlandia 105
UA - Ucraina 32
BE - Belgio 26
KR - Corea 24
TR - Turchia 22
CA - Canada 21
VN - Vietnam 21
JP - Giappone 14
IN - India 13
NL - Olanda 10
ES - Italia 9
ID - Indonesia 9
AT - Austria 7
BD - Bangladesh 7
ZA - Sudafrica 7
IQ - Iraq 5
LT - Lituania 5
MX - Messico 5
PL - Polonia 5
AE - Emirati Arabi Uniti 4
AU - Australia 4
UZ - Uzbekistan 4
AR - Argentina 3
CO - Colombia 3
IR - Iran 3
RO - Romania 3
TG - Togo 3
VE - Venezuela 3
BO - Bolivia 2
EU - Europa 2
GR - Grecia 2
IL - Israele 2
MD - Moldavia 2
NO - Norvegia 2
NP - Nepal 2
AM - Armenia 1
AZ - Azerbaigian 1
BY - Bielorussia 1
CL - Cile 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EC - Ecuador 1
GL - Groenlandia 1
HU - Ungheria 1
IM - Isola di Man 1
JO - Giordania 1
KG - Kirghizistan 1
MA - Marocco 1
MG - Madagascar 1
MK - Macedonia 1
MY - Malesia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
PT - Portogallo 1
PY - Paraguay 1
SA - Arabia Saudita 1
TH - Thailandia 1
TN - Tunisia 1
UY - Uruguay 1
Totale 5.474
Città #
Southend 435
Chandler 399
Jacksonville 265
Singapore 233
Woodbridge 210
Dallas 192
Ann Arbor 183
Ashburn 168
Hong Kong 142
Dublin 129
Verona 93
Beijing 87
New York 86
Houston 70
Wilmington 66
Jinan 52
Lawrence 50
Princeton 50
Munich 46
Nanjing 36
Hebei 26
Brussels 25
Los Angeles 24
The Dalles 22
Zhengzhou 21
Shenyang 20
Redmond 19
Tianjin 19
Columbus 18
Helsinki 17
Turku 16
Haikou 13
Hangzhou 13
Milan 13
San Francisco 13
Washington 13
Taizhou 12
Tokyo 12
Boardman 10
Nanchang 10
Santa Clara 10
São Paulo 10
Jakarta 9
Ningbo 9
Sindelfingen 9
Frankfurt am Main 8
Jiaxing 8
Toronto 8
Brooklyn 7
Dong Ket 7
Lanzhou 7
Redwood City 7
Seattle 7
Seoul 7
Taiyuan 7
Changsha 6
Fuzhou 6
Kent 6
Nuremberg 6
Padova 6
Rio de Janeiro 6
Boston 5
Caserta 5
Chennai 5
Council Bluffs 5
Guangzhou 5
London 5
Madrid 5
Roubaix 5
Atlanta 4
Campinas 4
Falls Church 4
Johannesburg 4
Lancaster 4
Montreal 4
Norwalk 4
Secaucus 4
Tashkent 4
Trieste 4
Amsterdam 3
Ankara 3
Augusta 3
Bexley 3
Boydton 3
Cape Town 3
Fairfield 3
Hefei 3
Kemerovo 3
Leawood 3
Lomé 3
Montréal 3
Mumbai 3
Porto Alegre 3
Ribeirão Preto 3
Riva 3
Salvador 3
Shanghai 3
Sorocaba 3
São Gonçalo 3
Treviso 3
Totale 3.627
Nome #
Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action. 149
BCL10 and PKC-zeta interactions in apoptosis of human cervical carcinoma cells triggered by etoposide 142
Amyloid-beta peptide induces HIF transcription factor and VEGF expression in cultured normal adult human astrocytes. 137
Abeta42 induction by its proxy, Abeta25-35, in cerebral normal human astrocytes requires calcium-sensing receptor (CaSR) signaling and nuclear translocation of HIF-1alpha/HIF-1beta complexes 135
Proteomic investigation into nonsyndromic aneurysm of the human ascenging aorta 133
CaSR INHIBITOR NPS2143 PREVENTS AMYLOID-β42 ACCUMULATION AND SECRETION IN NORMAL ADULT HUMAN ASTROCYTES AND POSTNATAL HUMAN NEURONS 131
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease 127
The calcium-sensing receptor: a novel Alzheimer’s disease crucial target? 126
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 124
Genomic and proteomic investigation into non-syndromic aneurysms of the human ascending aorta. 121
The Amyloid-β42 Proxy, Amyloid-β25-35, induces normal human cerebral astrocytes to produce Amyloid-β42. 120
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization 120
Involvement of protein kinase C-zeta at the nuclear membrane level of VP-16-treated human cervical carcinoma C4-I cells 119
How β-amyloid proteins and pro-inflammatory cytokines might collaborate to produce the “Alzheimer brain”. 119
JUNQUEIRA ISTOLOGIA TESTO ATLANTE 119
Analisi di espressione genica in aneurismi non sindromici dell’aorta ascendente 118
Proinflammatory cytokines and Amyloid β-(25-35) respectively stimulate VEGF-A production and secretion by cultured phenotypically normal adult human cerebral astrocytes 114
Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study 113
Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action. 109
Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action. 108
Proteomic investigations into non-syndromic aneurysms of the ascending aorta. 108
Soluble amyloid beta-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes 107
The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition 107
Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia 105
UCP2 inhibition induces ROS/Akt/mTOR axis: role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 103
Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis 102
The antioxidant mitochondrial protein UCP2 promotes cancer development connecting theWarburg effect and autophagy 102
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells 102
The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes 99
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis 99
Nuclear lamin B1 is selectively destroyed by phoexcited calphostin C in neoplastic human and rat cells. 98
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer's Disease. 98
Regulation of autophagy by nuclear GAPDH and its aggregates in cancer and neurodegenerative disorders 97
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells 96
Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review) 94
Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease? 93
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine 93
Molecular interplay between mutant p53 proteins and autophagy in cancer cells 92
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: an in depth proteomic study 92
Soluble amyloid β-peptide and myelin basic protein strongly stimulate, alone and in synergism with combined proinflammatory cytokines, the expression of functional nitric oxide synthase-2 in normal adult human astrocytes. 91
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease 91
Oncometabolites in cancer aggressiveness and tumour repopulation 90
Autocrine mechanisms of cancer chemoresistance 86
Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells - A novel mechanism of action of a photodynamic tumor therapy agent 84
Proteomic analysis of GTP cyclohydrolase I in multi-protein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions. 82
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells 81
Redox sensitive cysteine residues as crucial regulators of wild-type and mutant p53 isoforms 78
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC 78
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 77
Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells 75
Regulation of succinate dehydrogenase and role of succinate in cancer 70
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 68
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism 62
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 58
Totale 5.542
Categoria #
all - tutte 20.471
article - articoli 14.172
book - libri 0
conference - conferenze 5.624
curatela - curatele 318
other - altro 357
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.942


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021307 0 0 16 48 44 46 16 24 18 6 66 23
2021/2022429 51 114 3 16 26 8 7 31 17 12 34 110
2022/20231.049 67 138 82 198 84 242 9 68 119 5 26 11
2023/2024493 31 23 52 32 85 132 11 28 2 14 58 25
2024/20251.182 56 72 40 236 66 42 56 40 199 69 96 210
2025/2026513 261 172 80 0 0 0 0 0 0 0 0 0
Totale 5.542