Purpose: To evaluate MR features of neuroendocrine pancreatic tumors, comparing conventional sequences with DW sequences. Material and Methods: MR examinations of 39 patients with histology-proven pancreatic neuroendocrine tumors were retrospectively evaluated. Both a qualitative analysis (appearance, site, main pancreatic duct dilation, signal intensity) and a quantitative analysis (dimensions, degree of main pancreatic duct dilation, ADC value) were performed. Results: 69% of lesions were solid, mainly located in the pancreatic head (46%). Mean dimension was 31 mm; mean main pancreatic duct dilation was 7 mm. 79% of lesions did not determine ductal dilation. 74% of lesion were hypointense on T1-weighted images, 56% were hypointense on T1-weighted fat-suppressed images, 57% were hyperintense on T2-weighted fat- suppressed images; 59% of lesions were isointense in pancreatic phase images, 48% were hyperintense during the portal phase. Regarding DWI, 78% of lesions were hyperintense in b=800 images; the majority of T2-isointense lesions showed instead hyperintensity in b=800 images; the majority of isointense pancreatic-phase lesions were hyperintense in b=800 images. Mean ADC value was 1.38±0.2×10-3 mm2/s. Conclusion: DWI depicts a higher number of lesions in comparison with T2- weighted fat-suppressed and pancreatic-phase images, being therefore more sensitive for the identi cation of pancreatic neuroendocrine tumors.

MRI of pancreatic neuroendocrine tumors: added value of diffusion-weighted imaging

D'ONOFRIO, Mirko;DE ROBERTIS LOMBARDI, Riccardo;Crosara, Stefano;CANESTRINI, Stefano;POZZI MUCELLI, Roberto
2014-01-01

Abstract

Purpose: To evaluate MR features of neuroendocrine pancreatic tumors, comparing conventional sequences with DW sequences. Material and Methods: MR examinations of 39 patients with histology-proven pancreatic neuroendocrine tumors were retrospectively evaluated. Both a qualitative analysis (appearance, site, main pancreatic duct dilation, signal intensity) and a quantitative analysis (dimensions, degree of main pancreatic duct dilation, ADC value) were performed. Results: 69% of lesions were solid, mainly located in the pancreatic head (46%). Mean dimension was 31 mm; mean main pancreatic duct dilation was 7 mm. 79% of lesions did not determine ductal dilation. 74% of lesion were hypointense on T1-weighted images, 56% were hypointense on T1-weighted fat-suppressed images, 57% were hyperintense on T2-weighted fat- suppressed images; 59% of lesions were isointense in pancreatic phase images, 48% were hyperintense during the portal phase. Regarding DWI, 78% of lesions were hyperintense in b=800 images; the majority of T2-isointense lesions showed instead hyperintensity in b=800 images; the majority of isointense pancreatic-phase lesions were hyperintense in b=800 images. Mean ADC value was 1.38±0.2×10-3 mm2/s. Conclusion: DWI depicts a higher number of lesions in comparison with T2- weighted fat-suppressed and pancreatic-phase images, being therefore more sensitive for the identi cation of pancreatic neuroendocrine tumors.
Pancreas, Neuroendocrine neoplasms, MRI
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/947867
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