Pefloxacin concentrations were determined in necrotic pancreatic tissue and in serum of patients.High drug concentrations were determined in NPT. The NPT/serum ratio ranged from 0.9 to 5.1. The degree of necrosis seems an important factor of variavility in drug concentrations.
Pefloxacin penetration into human necrotic pancreatic tissue (NPT):
BERTAZZONI MINELLI, Elisa;BASSI, Claudio;PEDERZOLI, Paolo
1995-01-01
Abstract
Pefloxacin concentrations were determined in necrotic pancreatic tissue and in serum of patients.High drug concentrations were determined in NPT. The NPT/serum ratio ranged from 0.9 to 5.1. The degree of necrosis seems an important factor of variavility in drug concentrations.File in questo prodotto:
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