The importance of evaluating the role of folic acid supplementation is emerging. In particular, it is greatly interesting to consider whether high dosage folic acid supplementation may alter the levels of genomic DNA methylation which is known to be linked to cancer disease.
Folic acid effects on S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation in patients with intermediate hyperhomocysteinemia
PIZZOLO, Francesca;GIRELLI, Domenico;GUARINI, Patrizia;MARTINELLI, Nicola;CORROCHER, Roberto;OLIVIERI, Oliviero;FRISO, Simonetta
2010-01-01
Abstract
The importance of evaluating the role of folic acid supplementation is emerging. In particular, it is greatly interesting to consider whether high dosage folic acid supplementation may alter the levels of genomic DNA methylation which is known to be linked to cancer disease.
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