PACCHIANA, Raffaella
PACCHIANA, Raffaella
DIPARTIMENTO DI NEUROSCIENZE, BIOMEDICINA E MOVIMENTO
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death
2022-01-01 Pacchiana, Raffaella; Mullappilly, Nidula; Pinto, Andrea; Bova, Stefania; Forciniti, Stefania; Cullia, Gregorio; Dalla Pozza, Elisa; Bottani, Emanuela; Decimo, Ilaria; Dando, Ilaria; Bruno, Stefano; Conti, Paola; Donadelli, Massimo
Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia
2013-01-01 Armato, U.; Chakravarthy, B.; Pacchiana, R.; Whitfield, J. F.
Autocrine mechanisms of cancer chemoresistance
2018-01-01 Butera, Giovanna; Pacchiana, Raffaella; Donadelli, Massimo
Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease
2013-01-01 Armato, Ubaldo; Chiarini, Anna Maria; B., Chakravarthy; F., Chioffi; Pacchiana, Raffaella; E., Colarusso; J. F., Whitfield; DAL PRÀ, Ilaria Pierpaola
Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease
2014-01-01 DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria; Pacchiana, Raffaella; Gardenal, Emanuela; B., Chakravarthy; J. F., Whitfield; Armato, Ubaldo
Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis
2010-01-01 Chiarini, A.; Whitfield, J. F.; Pacchiana, R.; Marconi, M.; Armato, U.; Dal Pra, I.
Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action.
2006-01-01 Chiarini, Anna Maria; DAL PRÀ, Ilaria Pierpaola; Pacchiana, Raffaella; Menapace, Lia; G., Zumiani; M., Zanoni; Armato, Ubaldo
Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action.
2006-01-01 Chiarini, Anna Maria; DAL PRÀ, Ilaria Pierpaola; Pacchiana, Raffaella; Zumiani, G; Zanoni, M; Armato, Ubaldo
Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action.
2007-01-01 Dal, Prà; Chiarini, A.; Pacchiana, R.; Zumiani, G.; Zanoni, M.; Armato, U.
Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization
2014-01-01 Pacchiana, Raffaella; M., Abbate; Armato, Ubaldo; DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells
2023-01-01 Galbiati, Andrea; Bova, Stefania; Pacchiana, Raffaella; Borsari, Chiara; Persico, Marco; Zana, Aureliano; Bruno, Stefano; Donadelli, Massimo; Fattorusso, Caterina; Conti, Paola
Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?
2015-01-01 DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria; L., Gui; B., Chakravarthy; Pacchiana, Raffaella; Gardenal, Emanuela; J. F., Whitfield; Armato, Ubaldo
Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review)
2008-01-01 DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria; Pacchiana, Raffaella; B., Chakravarthy; J. F., Whitfield; Armato, Ubaldo
Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine
2021-01-01 Forciniti, Stefania; Dalla Pozza, Elisa; Greco, Maria Raffaella; Amaral Carvalho, Tiago Miguel; Rolando, Barbara; Ambrosini, Giulia; Carmona-Carmona, Cristian Andres; Pacchiana, Raffaella; Di Molfetta, Daria; Donadelli, Massimo; Arpicco, Silvia; Palmieri, Marta; Reshkin, Stephan Joel; Dando, Ilaria; Cardone, Rosa Angela
Molecular interplay between mutant p53 proteins and autophagy in cancer cells
2017-01-01 Cordani, Marco; Butera, Giovanna; Pacchiana, Raffaella; Donadelli, Massimo
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells
2018-01-01 Cordani, Marco; Butera, Giovanna; Dando, I.; Torrens-Mas, M.; Butturini, E.; Pacchiana, R.; Oppici, E.; Cavallini, C.; Gasperini, S.; Tamassia, N.; Nadal-Serrano, M.; Coan, M.; Rossi, D.; Gaidano, G.; Caraglia, M.; Mariotto, S.; Spizzo, R.; Roca, P.; Oliver, J.; Scupoli, M. T.; Donadelli, M.
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells
2020-01-01 Torrens-Mas, Margalida; Cordani, Marco; Mullappilly, Nidula; Pacchiana, Raffaella; Riganti, Chiara; Palmieri, Marta; Pons, Daniel G; Roca, Pilar; Oliver, Jordi; Donadelli, Massimo
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity
2018-01-01 Butera, G.; Pacchiana, R.; Mullappilly, N.; Margiotta, M.; Bruno, S.; Conti, P.; Riganti, C.; Donadelli, M.
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis
2016-01-01 Cordani, Marco; Pacchiana, Raffaella; Butera, Giovanna; D'Orazi, Gabriella; Scarpa, Aldo; Donadelli, Massimo
Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells
2020-01-01 Cordani, Marco; Butera, Giovanna; Pacchiana, Raffaella; Masetto, Francesca; Mullappilly, Nidula; Riganti, Chiara; Donadelli, Massimo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death | 1-gen-2022 | Pacchiana, Raffaella; Mullappilly, Nidula; Pinto, Andrea; Bova, Stefania; Forciniti, Stefania; Cullia, Gregorio; Dalla Pozza, Elisa; Bottani, Emanuela; Decimo, Ilaria; Dando, Ilaria; Bruno, Stefano; Conti, Paola; Donadelli, Massimo | |
| Alzheimer's disease: an update of the roles of receptors, astrocytes and primary cilia | 1-gen-2013 | Armato, U.; Chakravarthy, B.; Pacchiana, R.; Whitfield, J. F. | |
| Autocrine mechanisms of cancer chemoresistance | 1-gen-2018 | Butera, Giovanna; Pacchiana, Raffaella; Donadelli, Massimo | |
| Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease | 1-gen-2013 | Armato, Ubaldo; Chiarini, Anna Maria; B., Chakravarthy; F., Chioffi; Pacchiana, Raffaella; E., Colarusso; J. F., Whitfield; DAL PRÀ, Ilaria Pierpaola | |
| Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease | 1-gen-2014 | DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria; Pacchiana, Raffaella; Gardenal, Emanuela; B., Chakravarthy; J. F., Whitfield; Armato, Ubaldo | |
| Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis | 1-gen-2010 | Chiarini, A.; Whitfield, J. F.; Pacchiana, R.; Marconi, M.; Armato, U.; Dal Pra, I. | |
| Comano’s (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action. | 1-gen-2006 | Chiarini, Anna Maria; DAL PRÀ, Ilaria Pierpaola; Pacchiana, Raffaella; Menapace, Lia; G., Zumiani; M., Zanoni; Armato, Ubaldo | |
| Comano’s (Trentino) thermal water interferes with the interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action. | 1-gen-2006 | Chiarini, Anna Maria; DAL PRÀ, Ilaria Pierpaola; Pacchiana, Raffaella; Zumiani, G; Zanoni, M; Armato, Ubaldo | |
| Comano’s (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action. | 1-gen-2007 | Dal, Prà; Chiarini, A.; Pacchiana, R.; Zumiani, G.; Zanoni, M.; Armato, U. | |
| Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization | 1-gen-2014 | Pacchiana, Raffaella; M., Abbate; Armato, Ubaldo; DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria | |
| Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells | 1-gen-2023 | Galbiati, Andrea; Bova, Stefania; Pacchiana, Raffaella; Borsari, Chiara; Persico, Marco; Zana, Aureliano; Bruno, Stefano; Donadelli, Massimo; Fattorusso, Caterina; Conti, Paola | |
| Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease? | 1-gen-2015 | DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria; L., Gui; B., Chakravarthy; Pacchiana, Raffaella; Gardenal, Emanuela; J. F., Whitfield; Armato, Ubaldo | |
| Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an "Alzheimer brain" (Review) | 1-gen-2008 | DAL PRÀ, Ilaria Pierpaola; Chiarini, Anna Maria; Pacchiana, Raffaella; B., Chakravarthy; J. F., Whitfield; Armato, Ubaldo | |
| Extracellular matrix composition modulates the responsiveness of differentiated and stem pancreatic cancer cells to lipophilic derivate of gemcitabine | 1-gen-2021 | Forciniti, Stefania; Dalla Pozza, Elisa; Greco, Maria Raffaella; Amaral Carvalho, Tiago Miguel; Rolando, Barbara; Ambrosini, Giulia; Carmona-Carmona, Cristian Andres; Pacchiana, Raffaella; Di Molfetta, Daria; Donadelli, Massimo; Arpicco, Silvia; Palmieri, Marta; Reshkin, Stephan Joel; Dando, Ilaria; Cardone, Rosa Angela | |
| Molecular interplay between mutant p53 proteins and autophagy in cancer cells | 1-gen-2017 | Cordani, Marco; Butera, Giovanna; Pacchiana, Raffaella; Donadelli, Massimo | |
| Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells | 1-gen-2018 | Cordani, Marco; Butera, Giovanna; Dando, I.; Torrens-Mas, M.; Butturini, E.; Pacchiana, R.; Oppici, E.; Cavallini, C.; Gasperini, S.; Tamassia, N.; Nadal-Serrano, M.; Coan, M.; Rossi, D.; Gaidano, G.; Caraglia, M.; Mariotto, S.; Spizzo, R.; Roca, P.; Oliver, J.; Scupoli, M. T.; Donadelli, M. | |
| Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells | 1-gen-2020 | Torrens-Mas, Margalida; Cordani, Marco; Mullappilly, Nidula; Pacchiana, Raffaella; Riganti, Chiara; Palmieri, Marta; Pons, Daniel G; Roca, Pilar; Oliver, Jordi; Donadelli, Massimo | |
| Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity | 1-gen-2018 | Butera, G.; Pacchiana, R.; Mullappilly, N.; Margiotta, M.; Bruno, S.; Conti, P.; Riganti, C.; Donadelli, M. | |
| Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: involvement in cancer invasion and metastasis | 1-gen-2016 | Cordani, Marco; Pacchiana, Raffaella; Butera, Giovanna; D'Orazi, Gabriella; Scarpa, Aldo; Donadelli, Massimo | |
| Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells | 1-gen-2020 | Cordani, Marco; Butera, Giovanna; Pacchiana, Raffaella; Masetto, Francesca; Mullappilly, Nidula; Riganti, Chiara; Donadelli, Massimo |