Psoriasis is a chronic skin disease associated with deregulated interplays between immune cells and keratinocytes. Although a prominent skin infiltration of neutrophils is a distinctive hallmark feature of psoriatic inflammation (1), the role of neutrophils in psoriasis pathogenesis remains unclear. Aim of this study was to investigate the specific contribution of neutrophils during psoriatic inflammation.
Role of neutrophils in an imiquimod-induced mouse model of psoriasis
Scapini
2017-01-01
Abstract
Psoriasis is a chronic skin disease associated with deregulated interplays between immune cells and keratinocytes. Although a prominent skin infiltration of neutrophils is a distinctive hallmark feature of psoriatic inflammation (1), the role of neutrophils in psoriasis pathogenesis remains unclear. Aim of this study was to investigate the specific contribution of neutrophils during psoriatic inflammation.File in questo prodotto:
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