Fatty acids (FA) are not only fundamental constituents of cell structure, but also can modulate cellular functions with different effects according to their chain length and degree of saturation. Several evidences have linked FA profile with various pathological intermediate and clinical phenotypes, including dyslipidemia and hypertriglyceridemia. -3 polyunsaturated fatty acids (PUFAs) are well recognized as determinants of plasma triglyceride (TG) and their relative supplementation has been approved as TG-lowering therapy in hypertriglyceridemia. However, data on the other FA are sparse and generally controversial. The aim of the present study was to investigate the possible association between a complete FA profile and TG plasma concentration in a cohort of subjects with or with coronary artery disease (CAD).
Myristic acid plasma levels are strongly correlated with triglyceride and Apolipoprotein C-III plasma concentration in a cohort of subjects with or without coronary artery disease
CECCONI, Daniela;MARTINELLI, Nicola;OLIVIERI, Oliviero;CASTAGNA, Annalisa;GUARINI, Patrizia
2016-01-01
Abstract
Fatty acids (FA) are not only fundamental constituents of cell structure, but also can modulate cellular functions with different effects according to their chain length and degree of saturation. Several evidences have linked FA profile with various pathological intermediate and clinical phenotypes, including dyslipidemia and hypertriglyceridemia. -3 polyunsaturated fatty acids (PUFAs) are well recognized as determinants of plasma triglyceride (TG) and their relative supplementation has been approved as TG-lowering therapy in hypertriglyceridemia. However, data on the other FA are sparse and generally controversial. The aim of the present study was to investigate the possible association between a complete FA profile and TG plasma concentration in a cohort of subjects with or with coronary artery disease (CAD).
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