In this study we investigated how myeloid leukocytes may contribute to the breakdown of tolerance in lyn -/- mice. In particular, we have characterized the production of BAFF by lyn -/- myeloid cells and its possible involvement in the development of autoimmune disorders in this model.
Contribution of myeloid cell to the development of autoimmunity in Lyn-deficient mice.
SCAPINI, Patrizia;CASSATELLA, Marco Antonio;
2007-01-01
Abstract
In this study we investigated how myeloid leukocytes may contribute to the breakdown of tolerance in lyn -/- mice. In particular, we have characterized the production of BAFF by lyn -/- myeloid cells and its possible involvement in the development of autoimmune disorders in this model.
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