In this study we investigated how myeloid leukocytes may contribute to the breakdown of tolerance in lyn -/- mice. In particular, we have characterized the production of BAFF by lyn -/- myeloid cells and its possible involvement in the development of autoimmune disorders in this model.

Contribution of myeloid cell to the development of autoimmunity in Lyn-deficient mice.

SCAPINI, Patrizia;CASSATELLA, Marco Antonio;
2007-01-01

Abstract

In this study we investigated how myeloid leukocytes may contribute to the breakdown of tolerance in lyn -/- mice. In particular, we have characterized the production of BAFF by lyn -/- myeloid cells and its possible involvement in the development of autoimmune disorders in this model.
Src kinases, autoimmunity; myeloid cells
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/950667
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