The correlation between ALK gene copy number gain (ALK-CNG) and prognosis in the context of advanced non-small-cell lung cancer (NSCLC) remains a controversial issue. This study aimed to evaluate the association among ALK-CNG according to Fluorescent In Situ Hybridization (FISH), clinical characteristics and survival in resectable and advanced NSCLC.
ALK gene copy number gains in non-small-cell lung cancer: prognostic impact and clinico-pathological correlations
Peretti, Umberto;PILOTTO, Sara;Kinspergher, Stefania;CACCESE, MARIO;BRUNELLI, Matteo;Calio', Anna;CHILOSI, Marco;SCARPA, Aldo;
2016-01-01
Abstract
The correlation between ALK gene copy number gain (ALK-CNG) and prognosis in the context of advanced non-small-cell lung cancer (NSCLC) remains a controversial issue. This study aimed to evaluate the association among ALK-CNG according to Fluorescent In Situ Hybridization (FISH), clinical characteristics and survival in resectable and advanced NSCLC.
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