Dose equivalence of antidepressants is critically important for clinical practice and for research. There are several methods to define and calculate dose equivalence but for antidepressants, only daily defined dose and consensus methods have been applied to date. The purpose of the present study is to examine dose equivalence of antidepressants by a less arbitrary and more systematic method.

Dose equivalents of antidepressants: Evidence-based recommendations from randomized controlled trials

PURGATO, Marianna;CIPRIANI, Andrea;BARBUI, Corrado;
2015-01-01

Abstract

Dose equivalence of antidepressants is critically important for clinical practice and for research. There are several methods to define and calculate dose equivalence but for antidepressants, only daily defined dose and consensus methods have been applied to date. The purpose of the present study is to examine dose equivalence of antidepressants by a less arbitrary and more systematic method.
2015
Antidepressive agents; Dose equivalence; Fluoxetine; Major depression; Adult; Amitriptyline; Antidepressive Agents; Bupropion; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Moclobemide; Nortriptyline; Paroxetine; Randomized Controlled Trials as Topic; Serotonin Uptake Inhibitors; Sertraline; Treatment Outcome; Evidence-Based Medicine
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/947874
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