Considering the ample evidence of involvement of the glutamate system in the pathophysiology of depression, pre-clinical and clinical studies have been conducted to assess the antidepressant efficacy of glutamate inhibition, and glutamate receptor modulators in particular. This review focuses on the use of glutamate receptor modulators in unipolar depression.

Ketamine and other glutamate receptor modulators for depression in adults

CIPRIANI, Andrea
2015-01-01

Abstract

Considering the ample evidence of involvement of the glutamate system in the pathophysiology of depression, pre-clinical and clinical studies have been conducted to assess the antidepressant efficacy of glutamate inhibition, and glutamate receptor modulators in particular. This review focuses on the use of glutamate receptor modulators in unipolar depression.
TREATMENT-RESISTANT DEPRESSION, RANDOMIZED CONTROLLED-TRIAL, D-ASPARTATE ANTAGONIST, PLACEBO-CONTROLLED TRIAL, POSITIVE ALLOSTERIC MODULATOR, RAPID ANTIDEPRESSANT RESPONSE, STAR-ASTERISK-D, DOUBLE-BLIND, MAJOR DEPRESSION, ELECTROCONVULSIVE-THERAPY
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/937177
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