Silica nanoparticles (SNPs) are a promising carrier system for medical applications. They can be conveniently tailored with different moieties in order to obtain peculiar capabilities. SNPs surface is successfully modified in order to obtain a specific targeting ability through Boletus Edulis Lectin (BEL) bioconjugation, a lectin that specifically recognize overexpressed tumor markers. Moreover, stealthing abilities are imparted with a one-step cocondensation of silanated poly(ethylene) glycol monomethyl ether. Herein we present the preliminary results of these studies.
Titolo: | Stealth silica nanoparticles for theranostic applications | |
Autori: | ||
Data di pubblicazione: | 2013 | |
Abstract: | Silica nanoparticles (SNPs) are a promising carrier system for medical applications. They can be conveniently tailored with different moieties in order to obtain peculiar capabilities. SNPs surface is successfully modified in order to obtain a specific targeting ability through Boletus Edulis Lectin (BEL) bioconjugation, a lectin that specifically recognize overexpressed tumor markers. Moreover, stealthing abilities are imparted with a one-step cocondensation of silanated poly(ethylene) glycol monomethyl ether. Herein we present the preliminary results of these studies. | |
Handle: | http://hdl.handle.net/11562/616151 | |
Appare nelle tipologie: | 04.03 Poster |
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