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EnglishSilica nanoparticles (SNPs) are a promising carrier system for medical applications. They can be conveniently tailored with different moieties in order to obtain peculiar capabilities. SNPs surface is successfully modified in order to obtain a specific targeting ability through Boletus Edulis Lectin (BEL) bioconjugation, a lectin that specifically recognize overexpressed tumor markers. Moreover, stealthing abilities are imparted with a one-step cocondensation of silanated poly(ethylene) glycol monomethyl ether. Herein we present the preliminary results of these studies.
| Titolo: | Stealth silica nanoparticles for theranostic applications |
| Autori: | |
| Data di pubblicazione: | 2013 |
| Abstract: | Silica nanoparticles (SNPs) are a promising carrier system for medical applications. They can be conveniently tailored with different moieties in order to obtain peculiar capabilities. SNPs surface is successfully modified in order to obtain a specific targeting ability through Boletus Edulis Lectin (BEL) bioconjugation, a lectin that specifically recognize overexpressed tumor markers. Moreover, stealthing abilities are imparted with a one-step cocondensation of silanated poly(ethylene) glycol monomethyl ether. Herein we present the preliminary results of these studies. |
| Handle: | http://hdl.handle.net/11562/616151 |
| Appare nelle tipologie: | 04.03 Poster |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| NMS2013 Abstract collection page 32.pdf | Abstract |  | Open Access Visualizza/Apri |
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