The study of efficient methods to deduce fluxes of biological reactions, by starting from experimental data, is necessary to understand metabolic dynamics, and is a central issue in systems biology. In this paper we report some initial results, together with related open problems, regarding the efficient computation of regulation fluxes in metabolic P systems. By means of Log-gain theory the system dynamics can be linearized, in such a way to be described by a recurrence equations system, of which we point out a few algebraic properties, involving covering problems.

Regulation and covering problems in MP systems

FRANCO, Giuditta;MANCA, Vincenzo;
2010-01-01

Abstract

The study of efficient methods to deduce fluxes of biological reactions, by starting from experimental data, is necessary to understand metabolic dynamics, and is a central issue in systems biology. In this paper we report some initial results, together with related open problems, regarding the efficient computation of regulation fluxes in metabolic P systems. By means of Log-gain theory the system dynamics can be linearized, in such a way to be described by a recurrence equations system, of which we point out a few algebraic properties, involving covering problems.
2010
9783642114670
Block Matrices; Boolean Vectors; Log-gain Theory; Metabolic P systems; Regulation Fluxes.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/341687
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