Population genetic parameters of eight X-STR (DXS7132, DXS7423, DXS8378, DXS10074, DXS10101, DXS10134, DXS10135, HPRTB) markers located on the X-chromosome in four closely linkage groups were analysed in 176 unrelated Italian individuals (147 females and 29 males) using Mentype<sup>®</sup> Argus X-8 PCR Amplification Kit (Biotype). The Chi-square test for genotype distribution showed no significant deviation from Hardy-Weinberg equilibrium (HWE). Several microvariant and rare alleles have been observed in some of the X-STR markers studied. PIC of the eight X-STRs ranged from 0.617 to 0.925.
Genetic studies of eight X-STRs in a Northeast Italian population
TURRINA, Stefania;FILIPPINI, Giulia;DE LEO, Domenico
2009-01-01
Abstract
Population genetic parameters of eight X-STR (DXS7132, DXS7423, DXS8378, DXS10074, DXS10101, DXS10134, DXS10135, HPRTB) markers located on the X-chromosome in four closely linkage groups were analysed in 176 unrelated Italian individuals (147 females and 29 males) using Mentype® Argus X-8 PCR Amplification Kit (Biotype). The Chi-square test for genotype distribution showed no significant deviation from Hardy-Weinberg equilibrium (HWE). Several microvariant and rare alleles have been observed in some of the X-STR markers studied. PIC of the eight X-STRs ranged from 0.617 to 0.925.
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