PURPOSE. To evaluate the effects of pneumatic trabeculoplasty (PNT) in ocular hypertension and glaucoma subjects. METHODS. A total of 63 consecutive subjects, either treated (79\%) or untreated (21\%), with intraocular pressure (IOP) between 20 and 25 mmHg were enrolled; the eye with higher IOP (or, in case of identical IOP, worse visual field) was treated with PNT, with the fellow eye used as control. Subjects underwent a baseline evaluation the day before treatment, two PNT treatments at day 0 and 7, visits at day 1, 8, 14, and at each month until the end of the study, which lasted 6 months. Safety was addressed at all visits; an IOP curve (at 8 and 10 AM, 2 and 4 PM) was obtained at baseline and during monthly visits. RESULTS. In PNT eyes, baseline IOP was 22.2-/+1.6 mmHg. Following PNT a statistically significant reduction of IOP occurred at all visits (p<0.0001), with a mean decrease ranging from -2.7-/+2.5 (-11.9-/+10.8\%) to -3.6-/+2.6 mmHg (-16.0-/+11.6\%); mean reduction was 12.8-/+11.5\%. Although IOP diminished also in the control eyes after baseline (p<0.05), the change in IOP was significantly higher in PNT group at each visit (p<0.05). Mild side effects were experienced by 76\% of subjects and they all resolved without sequelae. CONCLUSIONS. The results suggest the effect of this procedure in reducing IOP in glaucoma and ocular hypertensive subjects.

The effect of pneumatic trabeculoplasty on intraocular pressure: The results of a 6-month, open-label, multicenter study.

MARCHINI, Giorgio;
2008-01-01

Abstract

PURPOSE. To evaluate the effects of pneumatic trabeculoplasty (PNT) in ocular hypertension and glaucoma subjects. METHODS. A total of 63 consecutive subjects, either treated (79\%) or untreated (21\%), with intraocular pressure (IOP) between 20 and 25 mmHg were enrolled; the eye with higher IOP (or, in case of identical IOP, worse visual field) was treated with PNT, with the fellow eye used as control. Subjects underwent a baseline evaluation the day before treatment, two PNT treatments at day 0 and 7, visits at day 1, 8, 14, and at each month until the end of the study, which lasted 6 months. Safety was addressed at all visits; an IOP curve (at 8 and 10 AM, 2 and 4 PM) was obtained at baseline and during monthly visits. RESULTS. In PNT eyes, baseline IOP was 22.2-/+1.6 mmHg. Following PNT a statistically significant reduction of IOP occurred at all visits (p<0.0001), with a mean decrease ranging from -2.7-/+2.5 (-11.9-/+10.8\%) to -3.6-/+2.6 mmHg (-16.0-/+11.6\%); mean reduction was 12.8-/+11.5\%. Although IOP diminished also in the control eyes after baseline (p<0.05), the change in IOP was significantly higher in PNT group at each visit (p<0.05). Mild side effects were experienced by 76\% of subjects and they all resolved without sequelae. CONCLUSIONS. The results suggest the effect of this procedure in reducing IOP in glaucoma and ocular hypertensive subjects.
2008
Glaucoma; Ocular hypertension; Intraocular pressure; Pneumatic trabeculoplasty; Pneumotrabeculoplasty
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/323261
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