The aim was to study fluoroquinolones intestinal concentrations and their potential interference with cells. Our preliminary results indicate that fluoroquinolones present different pharmacokinetic properties in relation to intestianal concentrations and may interfere with metabolic systems and interact with cellular DNA. These effects are dose-dependent and structure-specific
Fluoroquinolones (FQs) effects on enterocytes and lymphocytes.
BERTAZZONI MINELLI, Elisa;BENINI, Anna;DORIA, Denise;FRANCESCHETTI, Paola;FRACASSO, Maria Enrica
2003-01-01
Abstract
The aim was to study fluoroquinolones intestinal concentrations and their potential interference with cells. Our preliminary results indicate that fluoroquinolones present different pharmacokinetic properties in relation to intestianal concentrations and may interfere with metabolic systems and interact with cellular DNA. These effects are dose-dependent and structure-specific
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