A two-surgeon, two-center evaluation of a novel combined EDOF IOL approach

Purpose: To evaluate visual performance and quality of life after bilateral implantation of two extended depth of focus intraocular lenses (EDOF IOLs). Setting: Ophthalmology Clinic, Department of Medicine and Science of Ageing, University "G. d'Annunzio" Chieti-Pescara, Italy and Ophthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy. Design: Prospective clinical study. Methods: 60 eyes of 30 patients with senile cataract where enrolled in this study. Patients underwent phacoemulsification and bilateral implantation of the Mini WELL IOL (SIFI Medtech, Catania, Italy) in the dominant eye and the Mini WELL PROXA IOL (SIFI Medtech, Catania, Italy) in the non-dominant eye within a month. The main outcome measures over a 3-months follow-up period were: uncorrected and corrected visual acuity at different distances (33, 60 cm and 4 m), defocus curve, contrast sensitivity and patient's satisfaction (evaluated by mean of the NEI-RQL-42 questionnaire). Results: Binocular uncorrected visual acuity at 90 days was 0.03±0.11 logMAR for long distance, 0.05±0.10 logMAR for intermediate distance, 0.03±0.08 logMAR at 40 cm and 0.06±0.08 logMAR at 33 cm. Statistically significant differences between the two EDOF IOLs in favor of Mini WELL PROXA IOL were observed for uncorrected near visual acuity at 40 and 33 cm (p<0.001 and p<0.001, respectively) and for distance corrected near visual acuity at 40 cm (p<0.001). Significant differences between the two IOLs in the defocus curves were reported. Conclusions: In our small pilot study, bilateral implantation of Mini WELL IOL and Mini WELL PROXA IOL allowed to achieve good quantity and quality of vision.