Despite the introduction of non-invasive techniques in the study of peripheral neuropathies, sural nerve biopsy remains the gold standard for the diagnosis of several neuropathies, including vasculitic neuropathy and neurolymphomatosis. Besides its diagnostic role, sural nerve biopsy has helped to shed light on the pathogenic mechanisms of different neuropathies. In the present review, we discuss how pathological findings helped understand the mechanisms of polyneuropathies complicating hematological diseases.

Mechanisms of nerve damage in neuropathies associated with hematological diseases: lesson from nerve biopsies

Ferrari, Sergio;Tagliapietra, Matteo;Mariotto, Sara;Cavallaro, Tiziana
2021-01-01

Abstract

Despite the introduction of non-invasive techniques in the study of peripheral neuropathies, sural nerve biopsy remains the gold standard for the diagnosis of several neuropathies, including vasculitic neuropathy and neurolymphomatosis. Besides its diagnostic role, sural nerve biopsy has helped to shed light on the pathogenic mechanisms of different neuropathies. In the present review, we discuss how pathological findings helped understand the mechanisms of polyneuropathies complicating hematological diseases.
2021
lymphoma
monoclonal gammopathy
neurolymphomatosis
peripheral neuropathy
sural nerve biopsy
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1035463
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