MELOTTI, Paola Maria
MELOTTI, Paola Maria
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases
2022-01-01 Ghigo, Alessandra; Murabito, Alessandra; Sala, Valentina; Pisano, Anna Rita; Bertolini, Serena; Gianotti, Ambra; Caci, Emanuela; Montresor, Alessio; Premchandar, Aiswarya; Pirozzi, Flora; Ren, Kai; Della Sala, Angela; Mergiotti, Marco; Richter, Wito; de Poel, Eyleen; Matthey, Michaela; Caldrer, Sara; Cardone, Rosa A; Civiletti, Federica; Costamagna, Andrea; Quinney, Nancy L; Butnarasu, Cosmin; Visentin, Sonja; Ruggiero, Maria Rosaria; Baroni, Simona; Crich, Simonetta Geninatti; Ramel, Damien; Laffargue, Muriel; Tocchetti, Carlo G; Levi, Renzo; Conti, Marco; Lu, Xiao-Yun; Melotti, Paola; Sorio, Claudio; De Rose, Virginia; Facchinetti, Fabrizio; Fanelli, Vito; Wenzel, Daniela; Fleischmann, Bernd K; Mall, Marcus A; Beekman, Jeffrey; Laudanna, Carlo; Gentzsch, Martina; Lukacs, Gergely L; Pedemonte, Nicoletta; Hirsch, Emilio
Achromobacter spp. adaptation in cystic fibrosis infection and candidate biomarkers of antimicrobial resistance
2022-01-01 Veschetti, Laura; Saitta, Giulia Maria; Passarelli Mantovani, Rebeca; Carelli, Maria; Burlacchini, Gloria; Preato, Sara; Sorio, Claudio; Melotti, Paola; Montemari, Anna Lisa; Fiscarelli, Ersilia V; Patuzzo, Cristina; Signoretto, Caterina; Boaretti, Marzia; Lleò, Maria M; Malerba, Giovanni; Sandri, Angela
Adenine base editing with engineered virus-like particles rescues the CFTR mutation G542X in patient-derived intestinal organoids
2025-01-01 Nicosia, Lucia; Pranke, Iwona; Latorre, Roberta V.; Murray, Joss B.; Lonetti, Lisa; Cavusoglu-Doran, Kader; Dreano, Elise; Costello, James P.; Carroll, Michael; Melotti, Paola; Sorio, Claudio; Sermet-Gaudelus, Isabelle; Scallan, Martina F.; Harrison, Patrick T.
An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses
2017-01-01 Bergamini, Gabriella; Stellari, Fabio; Sandri, Angela; Lleo, Maria M.; Donofrio, Gaetano; Ruscitti, Francesca; Boschi, Federico; Sbarbati, Andrea; Villetti, Gino; Melotti, Paola Maria; Sorio, Claudio
An interactive computer program can effectively educate potential users of cystic fibrosis carrier tests.
2011-01-01 Castellani, Carlo; Perobelli, Sandra; V., Bianchi; M., Seia; Melotti, Paola Maria; L., Zanolla; Assael, Baroukhmaurice; F., Lalatta
Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium
2016-01-01 Leal, Teresinha; Bergamini, Gabriella; Huaux, François; Panin, Nadtha; Noel, Sabrina; Dhooghe, Barbara; Haaf, Jeremy B.; Mauri, Pierluigi; Motta, Sara; Di Silvestre, Dario; Melotti, Paola Maria; Sorio, Claudio
Biogenic selenium nanoparticles: characterization, antimicrobial activity and effects on human dendritic cells and fibroblasts
2016-01-01 Cremonini, Eleonora; Zonaro, Emanuele; Donini, Marta; Lampis, Silvia; Boaretti, Marzia; Dusi, Stefano; Melotti, Paola Maria; LLEO' FERNANDEZ, Maria Del Mar; Vallini, Giovanni
CFTR function is impaired in a subset of patients with pancreatitis carrying rare CFTR variants
2024-01-01 Angyal, Dora; Kleinfelder, Karina; Ciciriello, Fabiana; Groeneweg, Tessa A.; De Marchi, Giulia; de Pretis, Nicolò; Bernardoni, Laura; Rodella, Luca; Tomba, Francesco; De Angelis, Paola; Surace, Cecilia; Pintani, Emily; Alghisi, Federico; de Jonge, Hugo R.; Melotti, Paola; Sorio, Claudio; Lucidi, Vincenzina; Bijvelds, Marcel J. C.; Frulloni, Luca
CFTR Modulators Rescue the Activity of CFTR in Colonoids Expressing the Complex Allele p.[R74W;V201M;D1270N]/dele22_24
2023-01-01 Kleinfelder, Karina; Somenza, Elena; Farinazzo, Alessia; Conti, Jessica; Lotti, Virginia; Latorre, ROBERTA VALERIA; Rodella, Luca; Massella, Arianna; Tomba, Francesco; Bertini, Marina; Sorio, Claudio; Melotti, Paola
Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis
2019-01-01 Caldrer, Sara; Bergamini, Gabriella; Sandri, Angela; Vercellone, Silvia; Rodella, Luca; Cerofolini, Angelo; Tomba, Francesco; Catalano, Filippo; Frulloni, Luca; Buffelli, Mario; Tridello, Gloria; de Jonge, Hugo; Assael, Baroukh Maurice; Sorio, Claudio; Melotti, Paola
Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.
2011-01-01 Sorio, Claudio; Buffelli, Mario Rosario; Angiari, Chiara; Ettorre, Michele; Johansson, Jan Evert; Vezzalini, Marzia; Viviani, L.; Ricciardi, Mario; Verze', Genny; Assael, B. M.; Melotti, Paola Maria
Detection of CFTR protein in human leukocytes by flow cytometry.
2014-01-01 Johansson, Jan Evert; Vezzalini, Marzia; Verze', Genny; Caldrer, Sara; Bolognin, Silvia; Buffelli, Mario Rosario; Bellisola, Giuseppe; Tridello, G.; Assael, Baroukhmaurice; Melotti, Paola Maria; Sorio, Claudio
Effects of azithromycin on glutathione S-transferases in cystic fibrosis airway cells
2009-01-01 G., Bergamini; Cigana, Cristina; Sorio, Claudio; DELLA PERUTA, Marco; A., Pompella; A., Corti; F. A., Huaux; T., Leal; B. M., Assael; Melotti, Paola Maria
Evaluation of the response to elexacaftor-tezacaftor-ivacaftor of the rare CFTR variants L383S, I507del, L1065P and R1066H in intestinal organoid-derived epithelial monolayers
2025-01-01 Conti, Jessica; Angyal, Dora; Kleinfelder, Karina; Latorre, Roberta Valeria; Calicchia, Martina; Farinazzo, Alessia; Rodella, Luca; Tomba, Francesco; Massella, Arianna; Frulloni, Luca; Taccetti, Giovanni; Terlizzi, Vito; Leung, Anny; Groeneweg, Tessa A.; Bijvelds, Marcel J. C.; Melotti, Paola; Sorio, Claudio
Functional rescue of CFTR in rectal organoids from patients carrying R334W variant by CFTR modulators and PDE4 inhibitor Roflumilast
2024-01-01 Latorre, Roberta Valeria; Calicchia, Martina; Bigliardi, Martina; Conti, Jessica; Kleinfelder, Karina; Melotti, Paola; Sorio, Claudio
Genomic characterization of Achromobacter species isolates from chronic and occasional lung infection in cystic fibrosis patients
2021-01-01 Veschetti, Laura; Sandri, Angela; Patuzzo, Cristina; Melotti, Paola; Malerba, Giovanni; Lleo, Maria M
Guideline on the design and conduct of cystic fibrosis clinical trials: the European Cystic Fibrosis Society-Clinical Trials Network (ECFS-CTN).
2011-01-01 Melotti, Paola Maria; De Boeck K1, Bulteel V; ECFS CTN, network partners
HLA-G expression and regulation during Pseudomonas aeruginosa infection in cystic fibrosis patients
2016-01-01 Rizzo, Roberta; Bergamini, Gabriella; Bortolotti, Daria; Leal, Teresinha; D'Orazio, Ciro; Pintani, Emily; Melchiorri, Loredana; Zavatti, Eleonora; Assael, Baroukh M; Sorio, Claudio; Melotti, Paola Maria
Identification of Potential Leukocyte Biomarkers Related to Drug Recovery of CFTR: Clinical Applications in Cystic Fibrosis
2021-01-01 Pedrazzi, Marco; Vercellone, Silvia; Barberis, Elettra; Capraro, Michela; De Tullio, Roberta; Cresta, Federico; Casciaro, Rosaria; Castellani, Carlo; Patrone, Mauro; Marengo, Emilio; Lecca, Paola; Melotti, Paola; Sorio, Claudio; Manfredi, Marcello; Averna, Monica
Impact of polymorphism of Multidrug Resistance-associated Protein 1 (ABCC1) gene on the severity of cystic fibrosis.
2011-01-01 Mafficini, Andrea; Ortombina, M; Sermet Gaudelius, I; Lebecque, P; Leal, T; Iansa, Patrizia; Reychler, G; Dahan, K; Pepermans, X; Lenoir, G; Leonard, A; Sorio, Claudio; Assael, Baroukhmaurice; Melotti, Paola Maria
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases | 1-gen-2022 | Ghigo, Alessandra; Murabito, Alessandra; Sala, Valentina; Pisano, Anna Rita; Bertolini, Serena; Gianotti, Ambra; Caci, Emanuela; Montresor, Alessio; Premchandar, Aiswarya; Pirozzi, Flora; Ren, Kai; Della Sala, Angela; Mergiotti, Marco; Richter, Wito; de Poel, Eyleen; Matthey, Michaela; Caldrer, Sara; Cardone, Rosa A; Civiletti, Federica; Costamagna, Andrea; Quinney, Nancy L; Butnarasu, Cosmin; Visentin, Sonja; Ruggiero, Maria Rosaria; Baroni, Simona; Crich, Simonetta Geninatti; Ramel, Damien; Laffargue, Muriel; Tocchetti, Carlo G; Levi, Renzo; Conti, Marco; Lu, Xiao-Yun; Melotti, Paola; Sorio, Claudio; De Rose, Virginia; Facchinetti, Fabrizio; Fanelli, Vito; Wenzel, Daniela; Fleischmann, Bernd K; Mall, Marcus A; Beekman, Jeffrey; Laudanna, Carlo; Gentzsch, Martina; Lukacs, Gergely L; Pedemonte, Nicoletta; Hirsch, Emilio | |
| Achromobacter spp. adaptation in cystic fibrosis infection and candidate biomarkers of antimicrobial resistance | 1-gen-2022 | Veschetti, Laura; Saitta, Giulia Maria; Passarelli Mantovani, Rebeca; Carelli, Maria; Burlacchini, Gloria; Preato, Sara; Sorio, Claudio; Melotti, Paola; Montemari, Anna Lisa; Fiscarelli, Ersilia V; Patuzzo, Cristina; Signoretto, Caterina; Boaretti, Marzia; Lleò, Maria M; Malerba, Giovanni; Sandri, Angela | |
| Adenine base editing with engineered virus-like particles rescues the CFTR mutation G542X in patient-derived intestinal organoids | 1-gen-2025 | Nicosia, Lucia; Pranke, Iwona; Latorre, Roberta V.; Murray, Joss B.; Lonetti, Lisa; Cavusoglu-Doran, Kader; Dreano, Elise; Costello, James P.; Carroll, Michael; Melotti, Paola; Sorio, Claudio; Sermet-Gaudelus, Isabelle; Scallan, Martina F.; Harrison, Patrick T. | |
| An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses | 1-gen-2017 | Bergamini, Gabriella; Stellari, Fabio; Sandri, Angela; Lleo, Maria M.; Donofrio, Gaetano; Ruscitti, Francesca; Boschi, Federico; Sbarbati, Andrea; Villetti, Gino; Melotti, Paola Maria; Sorio, Claudio | |
| An interactive computer program can effectively educate potential users of cystic fibrosis carrier tests. | 1-gen-2011 | Castellani, Carlo; Perobelli, Sandra; V., Bianchi; M., Seia; Melotti, Paola Maria; L., Zanolla; Assael, Baroukhmaurice; F., Lalatta | |
| Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium | 1-gen-2016 | Leal, Teresinha; Bergamini, Gabriella; Huaux, François; Panin, Nadtha; Noel, Sabrina; Dhooghe, Barbara; Haaf, Jeremy B.; Mauri, Pierluigi; Motta, Sara; Di Silvestre, Dario; Melotti, Paola Maria; Sorio, Claudio | |
| Biogenic selenium nanoparticles: characterization, antimicrobial activity and effects on human dendritic cells and fibroblasts | 1-gen-2016 | Cremonini, Eleonora; Zonaro, Emanuele; Donini, Marta; Lampis, Silvia; Boaretti, Marzia; Dusi, Stefano; Melotti, Paola Maria; LLEO' FERNANDEZ, Maria Del Mar; Vallini, Giovanni | |
| CFTR function is impaired in a subset of patients with pancreatitis carrying rare CFTR variants | 1-gen-2024 | Angyal, Dora; Kleinfelder, Karina; Ciciriello, Fabiana; Groeneweg, Tessa A.; De Marchi, Giulia; de Pretis, Nicolò; Bernardoni, Laura; Rodella, Luca; Tomba, Francesco; De Angelis, Paola; Surace, Cecilia; Pintani, Emily; Alghisi, Federico; de Jonge, Hugo R.; Melotti, Paola; Sorio, Claudio; Lucidi, Vincenzina; Bijvelds, Marcel J. C.; Frulloni, Luca | |
| CFTR Modulators Rescue the Activity of CFTR in Colonoids Expressing the Complex Allele p.[R74W;V201M;D1270N]/dele22_24 | 1-gen-2023 | Kleinfelder, Karina; Somenza, Elena; Farinazzo, Alessia; Conti, Jessica; Lotti, Virginia; Latorre, ROBERTA VALERIA; Rodella, Luca; Massella, Arianna; Tomba, Francesco; Bertini, Marina; Sorio, Claudio; Melotti, Paola | |
| Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis | 1-gen-2019 | Caldrer, Sara; Bergamini, Gabriella; Sandri, Angela; Vercellone, Silvia; Rodella, Luca; Cerofolini, Angelo; Tomba, Francesco; Catalano, Filippo; Frulloni, Luca; Buffelli, Mario; Tridello, Gloria; de Jonge, Hugo; Assael, Baroukh Maurice; Sorio, Claudio; Melotti, Paola | |
| Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis. | 1-gen-2011 | Sorio, Claudio; Buffelli, Mario Rosario; Angiari, Chiara; Ettorre, Michele; Johansson, Jan Evert; Vezzalini, Marzia; Viviani, L.; Ricciardi, Mario; Verze', Genny; Assael, B. M.; Melotti, Paola Maria | |
| Detection of CFTR protein in human leukocytes by flow cytometry. | 1-gen-2014 | Johansson, Jan Evert; Vezzalini, Marzia; Verze', Genny; Caldrer, Sara; Bolognin, Silvia; Buffelli, Mario Rosario; Bellisola, Giuseppe; Tridello, G.; Assael, Baroukhmaurice; Melotti, Paola Maria; Sorio, Claudio | |
| Effects of azithromycin on glutathione S-transferases in cystic fibrosis airway cells | 1-gen-2009 | G., Bergamini; Cigana, Cristina; Sorio, Claudio; DELLA PERUTA, Marco; A., Pompella; A., Corti; F. A., Huaux; T., Leal; B. M., Assael; Melotti, Paola Maria | |
| Evaluation of the response to elexacaftor-tezacaftor-ivacaftor of the rare CFTR variants L383S, I507del, L1065P and R1066H in intestinal organoid-derived epithelial monolayers | 1-gen-2025 | Conti, Jessica; Angyal, Dora; Kleinfelder, Karina; Latorre, Roberta Valeria; Calicchia, Martina; Farinazzo, Alessia; Rodella, Luca; Tomba, Francesco; Massella, Arianna; Frulloni, Luca; Taccetti, Giovanni; Terlizzi, Vito; Leung, Anny; Groeneweg, Tessa A.; Bijvelds, Marcel J. C.; Melotti, Paola; Sorio, Claudio | |
| Functional rescue of CFTR in rectal organoids from patients carrying R334W variant by CFTR modulators and PDE4 inhibitor Roflumilast | 1-gen-2024 | Latorre, Roberta Valeria; Calicchia, Martina; Bigliardi, Martina; Conti, Jessica; Kleinfelder, Karina; Melotti, Paola; Sorio, Claudio | |
| Genomic characterization of Achromobacter species isolates from chronic and occasional lung infection in cystic fibrosis patients | 1-gen-2021 | Veschetti, Laura; Sandri, Angela; Patuzzo, Cristina; Melotti, Paola; Malerba, Giovanni; Lleo, Maria M | |
| Guideline on the design and conduct of cystic fibrosis clinical trials: the European Cystic Fibrosis Society-Clinical Trials Network (ECFS-CTN). | 1-gen-2011 | Melotti, Paola Maria; De Boeck K1, Bulteel V; ECFS CTN, network partners | |
| HLA-G expression and regulation during Pseudomonas aeruginosa infection in cystic fibrosis patients | 1-gen-2016 | Rizzo, Roberta; Bergamini, Gabriella; Bortolotti, Daria; Leal, Teresinha; D'Orazio, Ciro; Pintani, Emily; Melchiorri, Loredana; Zavatti, Eleonora; Assael, Baroukh M; Sorio, Claudio; Melotti, Paola Maria | |
| Identification of Potential Leukocyte Biomarkers Related to Drug Recovery of CFTR: Clinical Applications in Cystic Fibrosis | 1-gen-2021 | Pedrazzi, Marco; Vercellone, Silvia; Barberis, Elettra; Capraro, Michela; De Tullio, Roberta; Cresta, Federico; Casciaro, Rosaria; Castellani, Carlo; Patrone, Mauro; Marengo, Emilio; Lecca, Paola; Melotti, Paola; Sorio, Claudio; Manfredi, Marcello; Averna, Monica | |
| Impact of polymorphism of Multidrug Resistance-associated Protein 1 (ABCC1) gene on the severity of cystic fibrosis. | 1-gen-2011 | Mafficini, Andrea; Ortombina, M; Sermet Gaudelius, I; Lebecque, P; Leal, T; Iansa, Patrizia; Reychler, G; Dahan, K; Pepermans, X; Lenoir, G; Leonard, A; Sorio, Claudio; Assael, Baroukhmaurice; Melotti, Paola Maria |