Because increased enterocyte apoptosis has been associated with the pathogenesis of several chronic inflammatory diseases, the aim of our study was to investigate epithelial cell death in Crohn's disease and the possible role of the Fas-Fas ligand system, E-cadherin, and matrix metalloproteinase-1 in modulating enterocyte apoptosis in this condition.

Increased enterocyte apoptosis in inflamed areas of Crohn's disease

Ciccocioppo, Rachele;
2003-01-01

Abstract

Because increased enterocyte apoptosis has been associated with the pathogenesis of several chronic inflammatory diseases, the aim of our study was to investigate epithelial cell death in Crohn's disease and the possible role of the Fas-Fas ligand system, E-cadherin, and matrix metalloproteinase-1 in modulating enterocyte apoptosis in this condition.
Adolescent; Adult; Cadherins; Case-Control Studies; Crohn Disease; Enterocytes; Fas Ligand Protein; Female; Humans; In Situ Nick-End Labeling; Ki-67 Antigen; Ligands; Male; Matrix Metalloproteinase 1; Membrane Glycoproteins; Middle Aged; fas Receptor; Apoptosis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/998149
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