Because increased enterocyte apoptosis has been associated with the pathogenesis of several chronic inflammatory diseases, the aim of our study was to investigate epithelial cell death in Crohn's disease and the possible role of the Fas-Fas ligand system, E-cadherin, and matrix metalloproteinase-1 in modulating enterocyte apoptosis in this condition.

Increased enterocyte apoptosis in inflamed areas of Crohn's disease

Ciccocioppo, Rachele;
2003-01-01

Abstract

Because increased enterocyte apoptosis has been associated with the pathogenesis of several chronic inflammatory diseases, the aim of our study was to investigate epithelial cell death in Crohn's disease and the possible role of the Fas-Fas ligand system, E-cadherin, and matrix metalloproteinase-1 in modulating enterocyte apoptosis in this condition.
2003
Adolescent; Adult; Cadherins; Case-Control Studies; Crohn Disease; Enterocytes; Fas Ligand Protein; Female; Humans; In Situ Nick-End Labeling; Ki-67 Antigen; Ligands; Male; Matrix Metalloproteinase 1; Membrane Glycoproteins; Middle Aged; fas Receptor; Apoptosis
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/998149
Citazioni
  • ???jsp.display-item.citation.pmc??? 55
  • Scopus 133
  • ???jsp.display-item.citation.isi??? 127
social impact