Severe traumatic brain injury (TBI) may determine cerebral autoregulation derangements and cerebral blood flow (CBF) might become dependent on cerebral perfusion pressure (cPP). indeed, in healthy individuals CBF is adjusted by means of cerebral vessel vasodilatation and vasoconstriction, the so- called cerebral pressure autoregulation: the uninjured brain physiologically responds to variations in cerebral perfusion pressure (cPP) through constant modifications of CBF and vascular resistances.
Are we ready for automated optimal cerebral perfusion pressure?
Donadello, Katia;Gottin, Leonardo
2018-01-01
Abstract
Severe traumatic brain injury (TBI) may determine cerebral autoregulation derangements and cerebral blood flow (CBF) might become dependent on cerebral perfusion pressure (cPP). indeed, in healthy individuals CBF is adjusted by means of cerebral vessel vasodilatation and vasoconstriction, the so- called cerebral pressure autoregulation: the uninjured brain physiologically responds to variations in cerebral perfusion pressure (cPP) through constant modifications of CBF and vascular resistances.
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