Schistosomiasis affects more than 260 million people worldwide, mostly in sub-Saharan Africa, where more than 280.000 deaths per year are estimated. In the last few years, the increasing flow of migrants from endemic areas and the upward number of international travels have caused the emergence of the disease also in non-endemic areas. A single course of praziquantel (PZQ) 40 mg/kg is the first-line treatment recommended by the World Health Organization, mainly based on clinical trials conducted in endemic countries. No trials have been performed in non-endemic areas.
High-dose or Multi-day Praziquantel for Imported Schistosomiasis? A Systematic Review
Cucchetto, Giulia;Bisoffi, Zeno;
2019-01-01
Abstract
Schistosomiasis affects more than 260 million people worldwide, mostly in sub-Saharan Africa, where more than 280.000 deaths per year are estimated. In the last few years, the increasing flow of migrants from endemic areas and the upward number of international travels have caused the emergence of the disease also in non-endemic areas. A single course of praziquantel (PZQ) 40 mg/kg is the first-line treatment recommended by the World Health Organization, mainly based on clinical trials conducted in endemic countries. No trials have been performed in non-endemic areas.File in questo prodotto:
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