Epstein-Barr virus-positive (EBV(+)) diffuse large B-cell lymphoma (DLBCL) of the elderly is a variant of DLBCL with worse outcome that occurs most often in East-Asian countries and is uncommon in the Western hemisphere. We studied the largest cohort of EBV(+) DLBCL, independent of age, treated with rituximab combined with CHOP (R-CHOP) in developed Western countries.

Prevalence and clinical implications of epstein-barr virus infection in de novo diffuse large B-cell lymphoma in Western countries

Visco, Carlo;
2014-01-01

Abstract

Epstein-Barr virus-positive (EBV(+)) diffuse large B-cell lymphoma (DLBCL) of the elderly is a variant of DLBCL with worse outcome that occurs most often in East-Asian countries and is uncommon in the Western hemisphere. We studied the largest cohort of EBV(+) DLBCL, independent of age, treated with rituximab combined with CHOP (R-CHOP) in developed Western countries.
2014
Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cluster Analysis; Cyclophosphamide; Developed Countries; Doxorubicin; Epstein-Barr Virus Infections; Female; Gene Expression Profiling; Humans; Ki-1 Antigen; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; NF-kappa B; Neoplasm Staging; Phosphorylation; Prednisone; Prevalence; Survival Analysis; Treatment Outcome; Tumor Burden; Vincristine
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/993298
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