RNA sequencing to predict response to TNF-α inhibitors reveals possible mechanism for nonresponse in smokers

Cuppen, Bart V J; Rossato, Marzia; Fritsch-Stork, Ruth D E; Concepcion, Arno N; Linn-Rasker, Suzanne P; Bijlsma, Johannes W J; van Laar, Jacob M; Lafeber, Floris P J G; Radstake, Timothy R

doi:10.1080/1744666X.2018.1480937

Several studies have employed microarray-based profiling to predict response to tumor necrosis factor-alpha inhibitors (TNFi) in rheumatoid arthritis (RA); yet efforts to validate these targets have failed to show predictive abilities acceptable for clinical practice.

Titolo:	RNA sequencing to predict response to TNF-α inhibitors reveals possible mechanism for nonresponse in smokers
Autori:	Cuppen, Bart V J ROSSATO, Marzia Fritsch-Stork, Ruth D E Concepcion, Arno N Linn-Rasker, Suzanne P Bijlsma, Johannes W J van Laar, Jacob M Lafeber, Floris P J G Radstake, Timothy R mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2018
Rivista:	EXPERT REVIEW OF CLINICAL IMMUNOLOGY
Abstract:	Several studies have employed microarray-based profiling to predict response to tumor necrosis factor-alpha inhibitors (TNFi) in rheumatoid arthritis (RA); yet efforts to validate these targets have failed to show predictive abilities acceptable for clinical practice.
Handle:	http://hdl.handle.net/11562/993125
Appare nelle tipologie:	01.01 Articolo in Rivista

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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11562/993125

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