The International Prognostic Score (IPS) and circulating levels of the soluble form of CD30 molecule (sCD30) have both been associated with poor outcome in patients with advanced Hodgkin's lymphoma (HL). The aim of this study was to assess the prognostic power of the combined evaluation of sCD30 and IPS in these patients.

Serum levels of soluble CD30 improve International Prognostic Score in predicting the outcome of advanced Hodgkin's lymphoma

Zanotti, R;TROLESE, Anna Rita;Ambrosetti, A;Nadali, G;Visco, C;Pizzolo, G
2002

Abstract

The International Prognostic Score (IPS) and circulating levels of the soluble form of CD30 molecule (sCD30) have both been associated with poor outcome in patients with advanced Hodgkin's lymphoma (HL). The aim of this study was to assess the prognostic power of the combined evaluation of sCD30 and IPS in these patients.
Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy, Needle; Bleomycin; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Hodgkin Disease; Humans; International Cooperation; Ki-1 Antigen; Male; Mechlorethamine; Middle Aged; Multivariate Analysis; Neoplasm Staging; Predictive Value of Tests; Prednisone; Procarbazine; Prognosis; Proportional Hazards Models; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Survival Rate; Vinblastine; Vincristine
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/993055
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