Various destabilizing factors of the ubiquitin system contribute to the synchrony and unidirectionality of the cell cycle clock by finely tuning the activity of var- ious CDKs. The recent findings of hierarchical and connected waves of cyclin stabilizers highlight the complexity of this network.
Stabilizers and Destabilizers Controlling Cell Cycle Oscillators
Guardavaccaro, Daniele;
2006-01-01
Abstract
Various destabilizing factors of the ubiquitin system contribute to the synchrony and unidirectionality of the cell cycle clock by finely tuning the activity of var- ious CDKs. The recent findings of hierarchical and connected waves of cyclin stabilizers highlight the complexity of this network.
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