Accurate DNA replication is essential for genome mainte- nance. Two recent reports have uncovered new molecular mechanisms controlling the termination phase of DNA replication in higher eukaryotes and established crucial roles for the CRL2LRR1 ubiquitin ligase and the p97 segregase in replisome unloading from chromatin.
Two paths to let the replisome go
Guardavaccaro, Daniele
2017-01-01
Abstract
Accurate DNA replication is essential for genome mainte- nance. Two recent reports have uncovered new molecular mechanisms controlling the termination phase of DNA replication in higher eukaryotes and established crucial roles for the CRL2LRR1 ubiquitin ligase and the p97 segregase in replisome unloading from chromatin.
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