Gliadin presentation by HLA-DQ2/8 molecules to T cells plays a crucial role in triggering the inflammatory cascade in coeliac disease. We aimed to study the immunological effects of gliadin stimulation on dendritic cells (DCs) from HLA-DQ8 transgenic and BALB/c mice.

Effects of gliadin stimulation on bone marrow-derived dendritic cells from HLA-DQ8 transgenic MICE

Ciccocioppo, R;
2008-01-01

Abstract

Gliadin presentation by HLA-DQ2/8 molecules to T cells plays a crucial role in triggering the inflammatory cascade in coeliac disease. We aimed to study the immunological effects of gliadin stimulation on dendritic cells (DCs) from HLA-DQ8 transgenic and BALB/c mice.
2008
Animals; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Celiac Disease; Cell Differentiation; Cells, Cultured; Dendritic Cells; Gliadin; HLA-DQ Antigens; Interferon-alpha; Interleukins; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Transgenic; Toll-Like Receptors
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/991980
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