We report a case of Gorham-Stout disease (GSD) complicated by chylothorax and treated with a combination therapy with interferon and bisphosphonates. This treatment may be helpful in improving the usually unfavorable prognosis of GSD beginning with a chylothorax before 1 year of age, and in reducing bone lesions. Moreover, the use of bisphosphonates appears to be useful in treating pain.

A Child with Early-Onset Gorham-Stout Disease Complicated by Chylothorax: Near-Complete Regression of Bone Lesions with Interferon and Bisphosphonate Treatment

Ramaroli, Diego Alberto;Cavarzere, Paolo
;
Barillari, Marco;RODELLA, GIULIA;Gaudino, Rossella;Antoniazzi, Franco
2019-01-01

Abstract

We report a case of Gorham-Stout disease (GSD) complicated by chylothorax and treated with a combination therapy with interferon and bisphosphonates. This treatment may be helpful in improving the usually unfavorable prognosis of GSD beginning with a chylothorax before 1 year of age, and in reducing bone lesions. Moreover, the use of bisphosphonates appears to be useful in treating pain.
Alpha-2b interferon; Bisphosphonate; Chylothorax; Gorham-Stout disease;
Alpha-2b interferon; Bisphosphonate; Chylothorax; Gorham-Stout disease
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/989962
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