The duration of treatment with glucocorticoids (GC) in polymyalgia rheumatica (PMR) is often longterm. Amino bisphosphonates (N-BP) are used in PMR for the prevention of GC-induced osteoporosis, but they could also have immunomodulatory properties. Whether they can be effective as an adjuvant treatment in PMR is unknown. We aimed to establish whether the use of N-BP in our PMR cohort may be associated with GC discontinuation.
Permanent Discontinuation of Glucocorticoids in Polymyalgia Rheumatica is Uncommon but May Be Enhanced by Amino Bisphosphonates
Giollo, Alessandro;Rossini, Maurizio;Ghellere, Francesco;Fracassi, Elena;Idolazzi, Luca;Gatti, Davide;Viapiana, Ombretta
2018-01-01
Abstract
The duration of treatment with glucocorticoids (GC) in polymyalgia rheumatica (PMR) is often longterm. Amino bisphosphonates (N-BP) are used in PMR for the prevention of GC-induced osteoporosis, but they could also have immunomodulatory properties. Whether they can be effective as an adjuvant treatment in PMR is unknown. We aimed to establish whether the use of N-BP in our PMR cohort may be associated with GC discontinuation.
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