Combination therapy is a common strategy for treatment of multidrug resistant infections. Despite the strong twin rationales of improving efficacy and reducing resistance development, the evidence supporting this strategy remains controversial. The aims of this review are to assess the most recent studies supporting the use of combination therapy for treating infections because of carbapenem-resistant Enterobacteriaceae (CRE) and to highlight relevant areas for further research.

Combination versus monotherapy for the treatment of infections due to carbapenem-resistant Enterobacteriaceae

Carrara E;Bragantini D;Tacconelli E
2018-01-01

Abstract

Combination therapy is a common strategy for treatment of multidrug resistant infections. Despite the strong twin rationales of improving efficacy and reducing resistance development, the evidence supporting this strategy remains controversial. The aims of this review are to assess the most recent studies supporting the use of combination therapy for treating infections because of carbapenem-resistant Enterobacteriaceae (CRE) and to highlight relevant areas for further research.
2018
antibiotic resistance, combination therapy, evidence-based medicine
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/986179
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