Functional assessment of coronary lesions has become an integral part of routine practice in most cath labs. Such evaluation is performed using a pressure wire that allows measurement of fractional flow reserve (FFR). The latter has received a class I indication with level of evidence A according to the most recent European guidelines on myocardial revascularization for the assessment of angiographically moderate coronary lesions. The present document has the following objectives: 1) to summarize the theoretical basis of FFR; 2) to provide a guideline for vasodilator therapy; 3) to summarize scientific evidence supporting FFR; 4) to provide a model of health economy evaluation focusing on resource sparing associated with the use of FFR.

[Position paper on the theoretical basis, practical application and health economic evaluation of the functional assessment of coronary lesions endorsed by the Italian Society of Invasive Cardiology (SICI-GISE)]

Ribichini, Flavio;
2015-01-01

Abstract

Functional assessment of coronary lesions has become an integral part of routine practice in most cath labs. Such evaluation is performed using a pressure wire that allows measurement of fractional flow reserve (FFR). The latter has received a class I indication with level of evidence A according to the most recent European guidelines on myocardial revascularization for the assessment of angiographically moderate coronary lesions. The present document has the following objectives: 1) to summarize the theoretical basis of FFR; 2) to provide a guideline for vasodilator therapy; 3) to summarize scientific evidence supporting FFR; 4) to provide a model of health economy evaluation focusing on resource sparing associated with the use of FFR.
2015
Adenosine Triphosphate; Cardiac Catheterization; Clinical Trials as Topic; Collateral Circulation; Coronary Circulation; Coronary Stenosis; Diastole; Evidence-Based Medicine; Hemodynamics; Humans; Italy; Multicenter Studies as Topic; Myocardial Contraction; Nitroprusside; Papaverine; Vasodilator Agents; Fractional Flow Reserve, Myocardial; Heart Function Tests
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/980559
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