Rijo-Ferreira et al. report alterations of circadian rhythmicity at the behavioral, tissue, cellular, and molecular levels in mice after Trypanosoma brucei infection, showing that targeting cell clocks is a specific feature of these parasites. Thus, African trypanosomes cause a severe disease by disrupting time-keeping mechanisms and their synchrony.

Alive and ticking: Trypanosoma brucei assaults the circadian clocks

Bentivoglio, Marina
;
Bertini, Giuseppe
2018-01-01

Abstract

Rijo-Ferreira et al. report alterations of circadian rhythmicity at the behavioral, tissue, cellular, and molecular levels in mice after Trypanosoma brucei infection, showing that targeting cell clocks is a specific feature of these parasites. Thus, African trypanosomes cause a severe disease by disrupting time-keeping mechanisms and their synchrony.
Trypanosoma brucei; circadian rhythm; human African trypanosomiasis (HAT); PERIOD2::LUCIFERASE protein; murine model
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/976495
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