The postmenopausal state and rheumatoid arthritis (RA) lead to a significant decrease of both cortical and trabecular intra-articular bone density. This process in RA patients is a sign for a severe disease course predicting erosive disease.(2) Bone erosion is an important complication of RA and is associated with deformities and disabilities. Insufficient inhibition of structural joint damage by disease-modifying antirheumatic drugs (DMARDs) represents an unsolved problem and was reported despite clinical improvement.
Osteoporosis: an Independent Determinant of Bone Erosions in Rheumatoid Arthritis?
ROSSINI, Maurizio;ADAMI, GIOVANNI;VIAPIANA, Ombretta;IDOLAZZI, Luca;ORSOLINI, GIOVANNI;Fassio, Angelo;Giollo, Alessandro;GATTI, Davide
2017-01-01
Abstract
The postmenopausal state and rheumatoid arthritis (RA) lead to a significant decrease of both cortical and trabecular intra-articular bone density. This process in RA patients is a sign for a severe disease course predicting erosive disease.(2) Bone erosion is an important complication of RA and is associated with deformities and disabilities. Insufficient inhibition of structural joint damage by disease-modifying antirheumatic drugs (DMARDs) represents an unsolved problem and was reported despite clinical improvement.
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