Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience

Caminati, M; Senna, Gianenrico; Stefanizzi, G; Bellamoli, Rosanna; Longhi, Maria Serena; Chieco Bianchi, F; Guarnieri, Giovanni; Tognella, S; Olivieri, Monica; Micheletto, Claudio; Festi, Giuliana; Bertocco, E; Mazza, Ivana Maria; Rossi, Andrea; Vianello, Alice

doi:10.1186/s12890-016-0290-5

In patients with asthma, particularly severe asthma, poor adherence to inhaled drugs negatively affects the achievement of disease control. A better adherence rate is expected in the case of injected drugs, such as omalizumab, as they are administered only in a hospital setting. However, adherence to omalizumab has never been systematically investigated. The aim of this study was to review the omalizumab drop-out rate in randomized controlled trials (RCTs) and real-life studies. A comparative analysis was performed between published data and the Italian North East Omalizumab Network (NEONet) database.

Titolo:	Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience
Autori:	Caminati, Marco SENNA, GIANENRICO Stefanizzi, G BELLAMOLI, ROSANNA LONGHI, Maria Serena Chieco Bianchi, F GUARNIERI, Giovanni Tognella, S OLIVIERI, MONICA MICHELETTO, CLAUDIO FESTI, GIULIANA Bertocco, E MAZZA, Ivana Maria ROSSI, ANDREA VIANELLO, Alice mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2016
Rivista:	BMC PULMONARY MEDICINE
Abstract:	In patients with asthma, particularly severe asthma, poor adherence to inhaled drugs negatively affects the achievement of disease control. A better adherence rate is expected in the case of injected drugs, such as omalizumab, as they are administered only in a hospital setting. However, adherence to omalizumab has never been systematically investigated. The aim of this study was to review the omalizumab drop-out rate in randomized controlled trials (RCTs) and real-life studies. A comparative analysis was performed between published data and the Italian North East Omalizumab Network (NEONet) database.
Handle:	http://hdl.handle.net/11562/958304
Appare nelle tipologie:	01.01 Articolo in Rivista

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