In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.

Interfering with CCL5/CCR5 at the Tumor-Stroma Interface

Bronte, Vincenzo;Bria, Emilio
2016-01-01

Abstract

In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.
2016
Colorectal Neoplasms; Humans; Soft Tissue Neoplasms; Chemokine CCL5; Receptors, CCR5
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/953215
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