The predictive value of PIK3CA mutations in HER2 positive (HER2+) breast cancer treated with neoadjuvant anti-HER2 and chemotherapy has been reported, but the power for subgroup analyses was lacking.

PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab

Bria, Emilio;
2016-01-01

Abstract

The predictive value of PIK3CA mutations in HER2 positive (HER2+) breast cancer treated with neoadjuvant anti-HER2 and chemotherapy has been reported, but the power for subgroup analyses was lacking.
2016
HER2+ breast cancer; PIK3CA; double anti-HER2 treatment; neoadjuvant; pathological complete response; survival
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/953208
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