Microarray gene expression profiling has been widely applied to characterize hematologic malignancies, has attributed a molecular signature to leukemia subclasses and has allowed new subclasses to be distinguished. We set out to use microarray technology to identify novel genes relevant for leukemogenesis. To this end we used a unique leukemia-enriched cDNA microarray platform.

A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia

VITULO, Nicola;
2005-01-01

Abstract

Microarray gene expression profiling has been widely applied to characterize hematologic malignancies, has attributed a molecular signature to leukemia subclasses and has allowed new subclasses to be distinguished. We set out to use microarray technology to identify novel genes relevant for leukemogenesis. To this end we used a unique leukemia-enriched cDNA microarray platform.
2005
Adolescent; Bone Marrow; Child; Child, Preschool; Cluster Analysis; DNA, Complementary; Gene Library; Humans; Infant; Oligonucleotide Array Sequence Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sequence Analysis, DNA; Gene Expression Regulation, Neoplastic
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/951785
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