Purpose: The aim of the present study was to investigate the possibility to combine EEG and fMRI measures during finger movement in order to study the correlation between topographical changes in brain oscillatory activity over the scalp and the BOLD effect in the motor areas. Methods: Here we investigate the use of EEG and fMRI measurements during finger movement to evaluate the correlation between topographi- cal changes in brain oscillatory activity over the scalp and the BOLD effect in motor areas. Thirty-two channels of EEG were recorded in 9 subjects during eyes-open condition inside a 1.5 T magnetic resonance (MR) scanner using a MR-compatible EEG recording system. Off-line MRI artifact subtraction software was applied to obtain continuous EEG data during fMRI acquisition. For EEG data analysis we used the event- related-synchronization/desynchronization (ERS/ERD) approach to charac- terize where movement execution produces a decrease in alpha and beta power. For image statistical analysis we used a general linear model (GLM) approach. Results: There was a significant correlation between the BOLD peak and event-related-desynchronization values in the principal electrodes over the region of activation. Conclusion: The main finding of this study is the possibility to investigate the oscillatory activity of the brain inside a MRI scanner and that changes of the EMG or EEG signal can be useful to assess the possible sources of activation related to the BOLD effect.

Combining EEG and fMRI to investigate the cortical oscillatory activities during finger movement.

STORTI, Silvia Francesca;POZZI MUCELLI, Roberto;FIASCHI, Antonio;
2008

Abstract

Purpose: The aim of the present study was to investigate the possibility to combine EEG and fMRI measures during finger movement in order to study the correlation between topographical changes in brain oscillatory activity over the scalp and the BOLD effect in the motor areas. Methods: Here we investigate the use of EEG and fMRI measurements during finger movement to evaluate the correlation between topographi- cal changes in brain oscillatory activity over the scalp and the BOLD effect in motor areas. Thirty-two channels of EEG were recorded in 9 subjects during eyes-open condition inside a 1.5 T magnetic resonance (MR) scanner using a MR-compatible EEG recording system. Off-line MRI artifact subtraction software was applied to obtain continuous EEG data during fMRI acquisition. For EEG data analysis we used the event- related-synchronization/desynchronization (ERS/ERD) approach to charac- terize where movement execution produces a decrease in alpha and beta power. For image statistical analysis we used a general linear model (GLM) approach. Results: There was a significant correlation between the BOLD peak and event-related-desynchronization values in the principal electrodes over the region of activation. Conclusion: The main finding of this study is the possibility to investigate the oscillatory activity of the brain inside a MRI scanner and that changes of the EMG or EEG signal can be useful to assess the possible sources of activation related to the BOLD effect.
EEG, fMRI, finger movement
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/950406
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