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Alpha-fetoprotein (AFP) messenger RNA (mRNA) in the blood reflects the presence of circulating hepatocellular carcinoma (HCC) cells and is a sensitive marker of HCC extrahepatic metastases. The specificity of this molecular marker and its correlation with the main HCC clinical-pathological parameters remains controversial, however.

Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellular carcinoma

CARRARO, Amedeo;
2004-01-01

Abstract

Alpha-fetoprotein (AFP) messenger RNA (mRNA) in the blood reflects the presence of circulating hepatocellular carcinoma (HCC) cells and is a sensitive marker of HCC extrahepatic metastases. The specificity of this molecular marker and its correlation with the main HCC clinical-pathological parameters remains controversial, however.
2004
Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Colonic Neoplasms; DNA Primers; DNA, Neoplasm; Electrophoresis, Agar Gel; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Prognosis; Prospective Studies; RNA, Messenger; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; alpha-Fetoproteins
01.01 Articolo in Rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/944665
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