ACTH can induce the de novo DNA synthesis and the proliferation of normal adult human adrenocortical cells from zonae fasciculata and reticularis. The dose-related changes in the intensity of the incorporation of 3H-thymidine into DNA and of the mitogenic effects observed are likely due to complex hormonal mechanisms that need further study.
Dose-related persistent proliferogenic action of corticotrophin 1-24 in normal adult human adrenocortical cells in primary tissue culture
ARMATO, Ubaldo;
1977-01-01
Abstract
ACTH can induce the de novo DNA synthesis and the proliferation of normal adult human adrenocortical cells from zonae fasciculata and reticularis. The dose-related changes in the intensity of the incorporation of 3H-thymidine into DNA and of the mitogenic effects observed are likely due to complex hormonal mechanisms that need further study.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.