The high inter-individual variability of inhibition of platelet function by clopidogrel is mostly explained by high variability in its transformation to active metabolite (CAM).
Relationship between pharmacokinetics and pharmacodynamics of clopidogrel in patients undergoing percutaneous coronary intervention: comparison between vasodilator-stimulated phosphoprotein phosphorylation assay and multiple electrode aggregometry
DANESE, Elisa;FAVA, Cristiano;TAVELLA, Domenico;CALABRIA, Stefano;BENATI, Marco;GELATI, Matteo;GOTTARDO, Rossella;TAGLIARO, Franco;MINUZ, Pietro
2016-01-01
Abstract
The high inter-individual variability of inhibition of platelet function by clopidogrel is mostly explained by high variability in its transformation to active metabolite (CAM).
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