The high inter-individual variability of inhibition of platelet function by clopidogrel is mostly explained by high variability in its transformation to active metabolite (CAM).

Relationship between pharmacokinetics and pharmacodynamics of clopidogrel in patients undergoing percutaneous coronary intervention: comparison between vasodilator-stimulated phosphoprotein phosphorylation assay and multiple electrode aggregometry

DANESE, Elisa;FAVA, Cristiano;TAVELLA, Domenico;CALABRIA, Stefano;BENATI, Marco;GELATI, Matteo;GOTTARDO, Rossella;TAGLIARO, Franco;MINUZ, Pietro
2016-01-01

Abstract

The high inter-individual variability of inhibition of platelet function by clopidogrel is mostly explained by high variability in its transformation to active metabolite (CAM).
2016
VASP; Clopidogrel; Pharmacodynamics; Pharmacokinetics; acute coronary syndrome; impedance aggregometry; percutaneous coronary intervention; stable angina
File in questo prodotto:
File Dimensione Formato  
Clopidogrel_JThrombosis_2016.pdf

solo utenti autorizzati

Descrizione: Lavoro Clopidogrel JThrombosis_2016
Tipologia: Documento in Post-print
Licenza: Accesso ristretto
Dimensione 525.68 kB
Formato Adobe PDF
525.68 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/929726
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 17
  • ???jsp.display-item.citation.isi??? 13
social impact